PUBLICATIONS

Below you’ll find an overview of all our publications and presentations. If you have any questions concerning our scientific work, please feel free to contact us.

YearTitleAuthorsJournal/ConferenceCategory
2018Spatially Resolved Spectral Powder Analysis: Experiments and ModelingScheibelhofer O; Wahl PR; Larchevêque B; Chauchard F; Khinast JGApplied Spectroscopypaper refereed
2018Modeling of residence time distribution in a continuous dry granulation manufacturing line Karttunen AP; Martinetz MC; Sacher S; Wahl P; Khinast JG; Korhonen ONorthern Pharma Network (NPN)oral presentation
2018Continuous Multistep Synthesis Involving Unstable IntermediatesCantillo D8th FCS Flow Chemistry Europe, Cambridge, UKoral presentation
2018Is the Measured Coating Thickness Variation Real or Noise? Method Comparison for Monitoring of a Tablet Coating Process: OCT, NIR, Weight-, Height- and Diameter GainP.R. Wahl, A. Peter, M. Wolfgang, S. Sacher, J.G. KhinastIFPACoral presentation
2018Development and Implementation of a Control Strategy for a Pharmaceutical Feeding Blending UnitKhinast JGIFPAC 2018, Bethesda (USA)oral presentation
2018Continuous Multistep Synthesis of 2-Azidomethyl OxazolesRossa TA; Suveges NS; Sá MM; Cantillo D; Kappe COBeilstein Journal of Organic Chemistrypaper refereed
2018Voidage Correction Algorithm for Improved Heat and Mass Transfer Predictions in Unresolved Particle SimulationsAskarishahi M; Salehi M; Radl S2017 AIChE annual Meeting - Minneapolis Convention Centerpaper refereed
2018RTD-based Material Tracking in a Fully-Continuous Dry Granulation Tableting LineMartinetz M C; Karttunen A-P; Sacher S; Wahl P R; Korhonen O; J. Ketolainen; Khinast JGInternational Journal of Pharmaceuticspaper refereed
2018Synthesis of API Intermediates using Continuous Flow TechnologyCantillo DYoung Research Fellows Meeting, Orleans, Franceoral presentation
2018Real-time Optical Coherence Tomography (OCT) on Pharmaceutical Films and CoatingsP.R. Wahl, M. Wolfgang, A. Peter, S. Sacher, J.G. KhinastJPAG Continuous Manufacturingoral presentation
2018Control of Three Different Continuous Pharmaceutical Manufacturing Processes: Use of Soft SensorsRehrl J; Karttunen A-P; Nicolaï N; Hörmann T; Horn M; Korhonen O; Nopens I; De Beer T; Khinast JGInternational Journal of Pharmaceuticspaper refereed
2018Evaluation of New Opportunities for Pharmaceutical Manufacturing: Exploitation of Gas-Liquid Chemistry in FlowHone CCPAC / MK Optimization and Control Rome Workshop, Rome, Italyoral presentation
2018Evaluating the Tabletability of Hot-Melt Extruded Micro-pellets Prepared via Melt versus Strand PelletizingHörmann TR; Lopes D; Makert C; Witschnigg A; Khinast JG11th PBP World Meeting in Granada 2018poster presentation
2018Development of a Continuous Process for Drying of an Active Pharmaceutical IngredientAigner S; Kreimer M; Sacher S; Krumme M; Mannschott T; van der Wel P; Kaptein A; Khinast JG11th PBP World Meeting in Granada 2018poster presentation
2018In-situ On-demand Production of Anhydrous Diazomethane using Membrane Separation TechnologyDallinger D255th ACS National Meeting & Exposition, New Orleans, USoral presentation
2018Flow Enhancement of Ibuprofen Powder with two Glidant Types in a Continuous Blending Process Lachmann M; Martinetz M; Edinger P; Schaum V; Zakowiecki D; Heß T11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technologyposter presentation
2018Investigation of Coating Thickness Variations by Means of Optical Coherence TomographyPeter A, Wahl P, Wolfgang M, Sacher S, Khinast J11th PBP World Meeting in Granada 2018poster presentation
2018eXtended Particle System - High Performance Particle SimulationKureck HNvidia Graphics Technology Conference 2018poster presentation
2018Combinational Approach for Advanced Understanding of a Capsule Filling Process for DPI ProductsFaulhammer E; Stranzinger S; Calzolari V; Biserni S; Loidolt P; Paudel A; Khinast JMaking Pharmaceuticals Europeoral presentation
2018In-situ Generation of Anhydrous DiazomethaneWernik, MDoc Days 2018, Graz, Austriaoral presentation
2018Two-fluid Model Simulation of Wet Fluidized bedAskarishahi MMinisymposium Verfahrenstechnik 2018 and 4th Austrian Particle Forumoral presentation
2018Influence of powder composition on macroscopic powder propertiesFathollahi S; Faulhammer E; Khinast J14th Minisymposium Meeting in Linzposter presentation
2018Study of a Low-dose Capsule Filling Process by Dynamic and Static Tests for Advanced Process UnderstandingStranzinger S; Faulhammer E; Scheibelhofer O; Biserni S; Calzolari V; Paudel A; Khinast JGInternational Journal of Pharmaceuticspaper refereed
2018Commercial Readiness of XPS - Merging high-fidelity CFD-DEM simulations and reduced-order models through the “PSE-RCPE CoE”Forgber TAPM Forumoral presentation
2018Validation of CFD-DEM Simulation of a Continuous Tablet Coating Process Böhling PWorld Congress on Particle Technology (WCPT 8 )oral presentation
2018A patient-tailored Quality Risk Assessment for the development of nanoestructured DPI formulationsCorzo C; Zimmer A; Lochmann D; Salar-Behzadi S9th International Congress of Nanotechnology in Biology and Medicine, Graz, Austriaposter presentation
2018Strategies to Establish Mechanistic Liquid Transport Models for Wet Granular MatterKhinast JGWCPT 2018, Orlando (USA)oral presentation
2018Process Intensification and Integration Studies for the Generation of a Key Aminoimidazole Intermediate in the Synthesis of LanabecestatZnidar, D; Cantillo, D; Inglesby, P; Boyd, A; Kappe, COOrganic Process Research and Developmentpaper refereed
2018TFM simulation of wet fluidized bedAskarishahi MMinisymposium Verfahrenstechnikoral presentation
2018Combinational Approach for Advanced Understanding of a Capsule Filling Process for DPI ProductsFaulhammer E; Stranzinger S; Calzolari V; Biserni S; Loidolt P; Paudel A; Khinast JMaking Pharmaceuticals UKoral presentation
2018Hopper flow with non-convex polyhedral particles: GPU-based DEM simulations and experimental validationGovender N, Khinast JGChemical Engineering Sciencepaper refereed
2018Density fluctuations in amorphous pharmaceutical solids. Can SAXS help to predict stability?Laggner P; Paudel AColloids and Surfaces B: Biointerfacespaper refereed
2018Kreislaufwirtschaft: Industrieabfall als RohstoffKöckinger, M; Kappe, CONachrichten aus der Chemiepaper refereed
2018Effect of Technically Relevant X-Ray Doses on the Structure and Function of Alcohol Dehydrogenase and Hen Egg-White LysozymeSchaden L; Teubenbacher-Wimmer M; Poms J; Lohner K; Laggner P; Sacher S; Khinast JG; Salar-Behzadi SPharmaceutical Researchpaper refereed
2018Design and Construction of an Open Source-Based Photometer and its Applications in Flow ChemistryGlotz, G; Kappe, COReaction Chemistry and Engineeringpaper refereed
2018Assessment of dry powder inhaler carrier targeted design: a case-study comparing distinct anomeric compositions and physical properties of lactosePinto JT; Zellnitz S; Guidi T; Roblegg E; Paudel AMolecular Pharmaceuticspaper refereed
2018Investigation of Continuous Drying of Pharmaceuticals via ExtrusionKreimer M; Aigner I; Lepek D; Khinast JGOrganic Process Research & Development (ACS Publications)paper refereed
2018Improving Algorithms for Particle Simulation on Modern GPUsKureck HEuropean Seminar on Computing 2018 (ESCO 2018)oral presentation
2018eXtended Particle System - High Performance Particle SimulationKureck HEuropean Seminar on Computing 2018 (ESCO 2018)poster presentation
2018Simulating Complex Shaped Particles With DEMSiegmann EEuropean Seminar on Computing 2018 (ESCO 2018)oral presentation
2018Improving Algorithms for Particle Simulation on Modern GPUsKureck HEuropean Conference on Computational Mechanics (ECCM) 2018oral presentation
2018CFD-DEM Simulation of a Continuous Tablet Coating Process at Different Scales”Böhling PECCM – ECFD oral presentation
2018Large-scale GPU-enhanced DEM modeling of mixing of irregularly shaped particlesGovender N; Wilke DN; Wu C; Rajamani R; Khinast J; Glasser BAdvanced Powder Technology paper refereed
2018Large-scale GPU based DEM modeling of mixing using irregularly shaped particlesGovender NAdvanced Powder Technologypaper refereed
2018Adaptive Resolution in ExtrudersKondor I13th SPHERIC International Workshoporal presentation
2017Forbidden Chemistries – Paths to a Sustainable Future Engaging Continuous ProcessingGutmann B; Kappe COJournal of Flow Chemistrypaper refereed
2017Application of ICH Q9 quality risk management tools for advanced development of hot melt coated multiparticulate systemsStocker E; Becker K; Hate S; Hohl R; Schiemenz W; Sacher S; Zimmer A; Salar-Behzadi SInternational Journal of Pharmaceuticspaper refereed
2017The effect of material attributes and process parameters on the powder bed uniformity during a low-dose dosator capsule filling processStranzinger S; Faulhammer E; Calzolari V; Biserni S; Dreu R; Šibanc R; Paudel A; Khinast JGInternational Journal of Pharmaceuticspaper refereed
2017Analytical Solution for Thermal Transport in Packed Beds with Volumetric Heat SourceAskarishahi MChemical Engineering Journalpaper refereed
2017Design and Development of Pd-catalyzed Aerobic N-Demethylation Strategies for the Synthesis of Noroxymorphone in Continuous Flow ModeGutmann B; Cantillo C; Weigl U; Cox C.P; Kappe C.OEuropean Journal of Organic Chemistrypaper refereed
2017Microphase separation in solid lipid dosage forms as the cause of drug release instabilityLopes D; Koutsamanis I; Becker K; Haack D; Stehr M; Zimmer A; Salar-Behzadi SInternational Journal of Pharmaceuticspaper refereed
2017Analysis of the Active Drying Zone Within a Wurster Coater – CFD/DEM Simulation of Fluid Beds Including Heat TransferJajcevic DPSSRC Meeting 2017, Graz (AT)oral presentation
2017Continuous Flow Synthesis of Indoles by Pd-catalyzed Deoxygenation of 2-Nitrostilbenes with Carbon MonoxideGlotz G; Gutmann B; Hanselmann P; Kulesza A; Roberge D; Kappe C.ORSC Avdancespaper refereed
2017Regulatory Considerations for CM - Control Strategy and Batch DefinitionKhinast JGECCPM Workshop 2017, Graz (AT)oral presentation
2017Modeling the Flow of Bi-convex Tablets via True-Shape ObjectsKureck HJahrestreffen Bruchsal der ProcessNet-Fachgruppen AGG, GFSP, TRO, LVT, WSUEposter presentation
2017CFD DEM Simulations of an Industrial Scale Wurster CoaterBöhling PJahrestreffen Bruchsal der ProcessNet-Fachgruppen AGG, GFSP, TRO, LVT, WSUEoral presentation
2017Solutions for CM in Drug Product Aigner I; Kruisz J; Rehrl J; Wahl P; Faulhammer E; Sacher S; Khinast J.G
SSPC CM workshop 2017oral presentation
2017Using Optical Coherence Tomography (OCT) to Analyze Tablet Coating Variability of a Continuous Drum Coating ProcessWahl PR; Zettl M; Sacher S; Bastian R; Fränkel T; Khinast J.GIFPAC 2017, Bethesdaoral presentation
2017The Future of (Bio)Pharmaceutical ManufacturingKhinast JGPharma Ireland High-Level Seminar, Brüssel (BE)oral presentation
2017Model based control concept for a pharmaceutical direct compaction setupRehrl J; Martinetz M; Kruisz J; Sacher S; Horn M; Khinast JIFPAC 2017, Bethesdaoral presentation
2017Simulating convex polyhedral particles utilizing the discrete element methodSiegmann EGAMM (Gesellschaft für angewandte Mathematik und Meachnik) annual Meetingoral presentation
2017Measuring On-Line Residence Time Distribution in Melt Extrusion via Video AnalysisWahl P.R.; Hörl G; Kaiser D; Sacher S; Rupp C; Shlieout G; Breitenbach J; Koscher G; Khinast J.GPolymer Engineering & Sciencepaper refereed
2017Orodispersible films: Towards Drug Delivery in Special PopulationsPaudel A; Scarpa M; Orlu Gul; Gaisford S; Stegemann S; Bresciani M; Pichler HInternational Journal of Pharmaceuticspaper refereed
2017Lipid-Based Pharmaceutical Formulations for Patient-Centric Product DevelopmentSalar-Behzadi S; Becker K; Lopes D; Zimmer A; Lochmann DInvited Key Note Lecture in 10th International Conf on Pharmaceutics and Novel Drug Delivery Systems 13th- 15th March 2017oral presentation
2017Micro-Feeding and Dosing of Powders via a Small-Scale Powder-PumpBesenhard MO; Fathollahi S; Siegmann E; Slama E; Faulhammer E; Khinast JGInternational Journal of Pharmaceuticspaper refereed
2017Continuous Manufacturing – Critical Steps and Possible SolutionsKhinast JG8th annual global drug delivery and formulation summit, Berlin (DE)oral presentation
2017Optical Coherence Tomography of Multilayer-Tablets to examine Potential Critical Quality AttributesPoms J; Scheibelhofer O; Sacher S; Khinast J.GMinisymposium 2017; Innsbruck (AT)poster presentation
2017A Coarse-Grid CFD-DEM Model for Multi-physics Simulations of Dense Gas-Particle FlowsAskarishahi M, Kureck HMinisymposium 2017; Innsbruck (AT)poster presentation
2017Small-scale Continuous Drying of Powders via Extrusion avoiding Agglomeration or Attrition of the Final ProductKreimer M; Aigner S; Khinast J.GMinisymposium 2017; Innsbruck (AT)poster presentation
2017Comparison of Video Analysis and Simulations of a Drum Coating ProcessBoehling P; Toschkoff G; Dreu R; Just S; Knop K; Kleinebudde P; Funke A; Rehbaum H; Rajniak P; Khinast J.KEuropean Journal for Pharmaceutical science paper refereed
2017Reaction Calorimetry in Microreactor Environments - Measuring Heat of Reaction by Isothermal Heat Flux CalorimetryGlotz G; Knoechel DJ; Podmore P; Gruber-Woelfler H; Kappe COOrganic Process Research & Developmentpaper refereed
2017A Coarse-Grid CFD-DEM Model for Multi-physics Simulations of Dense Gas-Particle FlowsAskarishahi MMinisymposium 2017; Innsbruck (AT)oral presentation
2017A time-dependent study on the impact of engineering on the physicochemical characteristics of inhalable particlesPinto JT; Radivojev S; Zellnitz S; Khinast J.G; Roblegg E; Paudel A2nd European Congress on Pharmaceutics, April 2017; Krakow (PL)Oral Presentation
2017RTD Modeling of a Continuous Dry Granulation Process for Process Control and Materials Diversion Kruisz J; Rehrl J; Sacher S; Aigner I; Horn M; Khinast JGInternational Journal Pharmaceuticspaper refereed
2017Reaction Calorimetry in Microreactor Environments – Measuring Heat of Reaction by Isothermal Heat Flux CalorimetryGlotz G; Knoechel D; Podmore P; Gruber-Woelfler H; Kappe C.OOrganic Process Research and Developmentpaper refereed
2017A combined DEM & FEM approach for modelling roll compaction processMazora A; Orefice L; Michrafy M; Ryck A; Khinast JGPowder Technologypaper refereed
2017gSOLIDS simulation of fluid bed granulation processSushil SAPM forum 2017oral presentation
2017A study of shape non-uniformity and poly-dispersity in hopper discharge of spherical and polyhedral particle systems using the BlazeDEM3D-GPU codeGovender N; Wilke DN; Pizettec P; Abriak NEMaths and Computationpaper refereed
2017Development of nanostructered lipid carriers for intraoral delivery of DomperidoneTetyczka C; Griesbacher M; Absenger-Novak M; Fröhlich E; Roblegg EInternational Journal of Pharmaceuticspaper refereed
2017How does secondary processing affect the physicochemical properties of inhalable salbutamol sulphate particles ? A temporal investigationPinto JT; Radivojev S; Zellnitz S; Roblegg E; Paudel AInternational Journal of Pharmaceuticspaper refereed
2017Gluing Pills Technology for the Production of Multi-Layer TabletsSalar-Behzadi S; Sacher S; Lingitz J; Khinast JPharmTechpaper refereed
2017Establishment of a molding procedure to facilitate formulation development for co-extrudatesEder S; Beretta M; Witschnigg A; Koutsamanis I; Eggenreich K; Khinast J; Koscher G; Paudel A; Nickisch K; Friedrich M; Froehlich E; Roblegg EAAPS PharmSciTechpaper refereed
2017A NIRly controlled processScheibelhofer O; Rehrl J; Sacher S; Khinast J.GSentronic PAT Meetingoral presentation
2017eXtended Particle System - High-Performance Particle SimulationKureck HGPU Technology Conference 2017; Silicon Valley (US)poster presentation
2017Large Scale Polyhedra Simulations on the GPUGovender NGPU Technology Conference 2017; Silicon Valley (US)oral presentation
2017Development of a Continuous-Flow Process for a Pd-Catalyzed Olefin Cleavage using Oxygen within the Explosive RegimeHone C; O’Kearney-McMullan A; Munday R; Kappe C.OChemCatChempaper refereed
2017Impacts and Paradigms Enabled by GPUs in Engineering Simulations of Discrete ElementsGovender NGpu Technologie Conference 2017oral presentation
2017Impulse-Based Dynamics for Studying Quasi-static Granular Flows: Application to Hopper Emptying of Non-spherical ParticleToson PChemical Engineering Sciencepaper refereed
2017Challenges for Continuous Capsule FillingKruisz J; Rehrl J; Scheibelhofer O; Faulhammer E; Witschnigg A; Khinast J.G.PSSRC Meeting 2017, Graz (AT)
2017A technology assessment for inspection of lyophilized productsPoms J; Dekner M; Sacher S; Schennach R; Khinast JGPSSRC Meeting 2017, Graz (AT)oral presentation
2017Mechanical properties of microspheres produced by drying of levitated suspension dropletsKreimer M; Aigner S; Sacher S; Krumme M; Mannschott T; van der Wel P; Kaptein A; Schröttner H; Brenn G; Khinast JGPSSRC Meeting 2017, Graz (AT)oral presentation
2017Hydrogen Sulfide Chemistry in Continuous Flow: Efficient Synthesis of 2-OxopropanethioamideCantillo D; Inglesby P.A; Boyd A; Kappe C.OJournal of Flow Chemistrypaper refereed
2017Development of a Continuous-Flow Sonogashira Cross-Coupling Protocol using Propyne Gas under Process Intensified ConditionsZnidar D; Hone C; Inglesby P; Boyd A; Kappe C..OOrganic Process Research and Developmentpaper refereed
2017A novel continuous process for the isolation of pure paracetamol: directly coupled synthesis and crystallization in continuous flow Gruber-Woelfler H; Brown CJ; Svoboda V; MacFhionnghaile P; Florence AJJT Reaktionstechnik 2017poster presentation
2017Impact of salbutamol sulphate particle properties on the tribocharging of inhalable mixtures Pinto JT; Zellnitz S; Roblegg E; Paudel APSSRC Meeting 2017; Graz (AT)oral presentation
2017Toxicity of orally inhaled drug formulations at the alveolar barrier: parameters for initial biological screeningFroehlich EDrug Deliverypaper refereed
2017Why flow means green – Evaluating the merits of continuous processing in the context of sustainabilityDallinger, D; Kappe, COCurrent Opinion in Green and Sustainable Chemistrypaper refereed
2017Long Term Coating Predictions in a Large Scale Wurster Coater Based on CFD DEM SimulationsBöhling PCoupled Problems 2017oral presentation
2017Continuous Flow Difluoromethylation with Chlorodifluoromethane under Biphasic ConditionsGutmann B; Hanselmann P; Bersier M; Roberge D; Kappe C.OJournal of Flow Chemistrypaper refereed
2017Continuous Flow Synthesis of Carbonylated Heterocycles via Pd-Catalyzed Oxidative Carbonylation Using CO and O2 at Elevated Temperature and PressureChen Y; Hone CA; Gutmann B; Kappe COOrganic Process Research and Developmentpaper refereed
2017Strategies for Optimizing a Low-Dose Dosator Capsule Filling Process for Inhalation Application ProductsStranzinger S; Faulhammer E; Scheibelhofer O; Biserni S; Calzolari V; Paudel A; Khinast J.G11th Annual Meeting of the Pharmaceutical Solid State Research Cluster (PSSRC) 2017. Graz (AT)oral presentation
2017Modeling of Residence Time Distribution of a Continuous Dry Granulation Tableting LineMartinetz MC; Karttunen A-P; Sacher S; Wahl PR; Korhonen O; Khinast J.GAIChE Annual Meeting 2017, Minneapolis (US)oral presentation
2017Residence time distribution modeling and experimental validation of a continuous dry granulation tableting lineMartinetz MC; Karttunen A-P; Sacher S; Wahl P R; Korhonen O; Khinast JGPSSRC Meeting 2017, Graz (AT)oral presentation
2017DEM Feeder Discharge, Material TrackingToson PPSSRC Meeting 2017, Graz (AT)oral presentation
2017Modeling an Industrial-Scale Fluidized Bed Wurster Coating Process Using CFD-DEMJajcevic DISC 2017oral presentation
2017Advanced control strategies for continuous manufacturing of solid dosage formsSacher S; Rehrl J; Kruisz J; Martinetz M; Aigner I; Scheibelhofer O; Khinast JGPSSRC Meeting 2017, Graz (AT)oral presentation
2017An Integrated Continuous Flow Synthesis of a Key Oxazolidine Intermediate to Noroxymorphone from Naturally Occurring OpioidsMata A; Cantillo D; Kappe C.OEuropean Journal of Organic Chemistrypaper refereed
2017SPH-DEM with polyhedral particlesKondor ISPHERIC 2017oral presentation
2017The impact of mechano activation on drug stabilityGressl C; Brunsteiner M; Paudel A; Davis A; Landis M; Pencheva K; Scrivens G; Sluggett GW; Wood RPF; Gruber-Wölfler H; Khinast JGPSSRC Meeting 2017, Graz (AT)oral presentation
2017In vitro release of estradiol from ethylene-vinyl acetate based reservoir type systemsKoutsamanis I; Eder S; Paudel A; Nickisch K; Friedrich M; Roblegg EPSSRC Meeting 2017, Graz (AT)Oral presentation
2017Potential for Interactive Simulation Design in Discrete Element ModellingGovender NPowders and Grains paper refereed
2017DEM GPU studies of industrial scale particle simulations for granular flow civil engineering applicationsPizette P; Govender N; Wilke DN; Abriak NEPowders and Grains 2017paper refereed
2017Efficient Discrete Element Method Simulation Strategy for Analyzing Large-Scale Agitated Powder MixersSiegmann E; Jajcevic D; Khinast J.GWiley-VCHpaper refereed
2017Synthesis of Mepivacaine and its Analogues by a Continuous Flow Tandem Hydrogenation−Reductive Amination StrategySuveges NS; de Souza ROMA; Gutmann B; Kappe COEuropean Journal of Organic Chemistrypaper refereed
2017A Continuous Operation Concept for a Rotary Tablet Press Using Mass Flow Operating Points
Martinetz M; Aigner S; Rehrl J; Sacher S; Khinast JChemie Ingenieur Technikpaper refereed
2017An investigation of the hydrodynamic similarity of single-spout fluidized beds using CFD-DEM simulationsEbrahimi M; Siegmann E; Prieling D; Glasser BJ; Khinast JGAdvanced Powder Technology paper refereed
2017Comparison of NIR Spectroscopy with DEM Simulation for Tracing the Spatial Dispersion of water during MixingHohl R; Radeke C; Heigl N; Koller DParticuologypaper refereed
2017Effect of acetonitrile-based crystallization conditions on the crystal quality of Vitamin D3Escriba-Gelonch M; Hessel V; Noel T; Maier M; Gruber-Woelfler HChem Eng Techn.paper refereed
2017Industrial granular media simulations on the GPUGovender NPowders and Grainsoral presentation
2017Combinational approach for advanced understanding of a low dose capsule filling process for inhalation application Faulhammer E; Stranzinger S; Calzolari V; Biserni S; Loidolt P; Paudel A; Khinast JDDL2017; Edinburgh (UK)poster presentation
2017Influence of Melt Compounding on Blast Furnace Slag Filled PP Compounds: A Comparative StudyMostafa A; Pacher G; Lucyshyn T; Holzer C; Krischey E; Flachberger H; Fritz B; Laske SInternational Polymer Processingpaper refereed
2017Continuous Flow Synthesis of Indoles by Pd-catalyzed Deoxygenation of 2-Nitrostilbenes with Carbon MonoxideGlotz G26th ISHC congress; Regensburg (GE)poster presentation
20173D Printing of Oral Drugs - a new Reality or Hype?Hsiao W-K; Lorber B; Reitsamer H; Khinast JExpert Opinion on Drug Deliverypaper refereed
2017Lab-scale production of anhydrous diazomethane using membrane separation technologyDallinger D; Kappe CONature Protocolspaper refereed
2017A Voidage Correction Model for Improved Predictions of Hydrodynamics in Unresolved Euler-Lagrange SimulationsAskarishahi M; Salehi M; Radl SCFDEM Workshop 2017oral presentation
2017A Novel Approach to Calculate Radiative Thermal Exchange in Coupled Particle SimulationsForgber TCFDEM CONFERENCE 2017oral presentation
2017DEM Simulations of a Twin-Screw Feeder for Material Tracking and Optimizing Refill StrategiesToson PECCPM 2017 (European Consortium for Continous Pharmaceutical Manufacturing)poster presentation
2017Approaches for the In Vitro Evaluation of Taste-Masking in PaediatricSalar-Behzadi S; Zimmer A; Bresciani MEuropean Paedriatic Formulation Initiative 2017; Antwerp (BEL)Oral presentation
2017An investigation on cohesion between particles due to liquid bridges in the pendular regimePatsaki NParticles 2017oral presentation
2017Simulating convex polyhedral particles utilizing the discrete element method on GPUSiegmann EParticles 2017oral presentation
2017Largs scale polyhedral particlesGovender NParticles 2017oral presentation
2017Voidage and Fluid Speed Correction Algorithms for Improved Heat and Mass Transfer  Predictions in Unresolved Particle SimulationsAskarishahi MParticles 2017oral presentation
2017TBA - Merck - GEA Tablet Coating - DoE small coaterBöhling PParticles 2017oral presentation
2017Geometric Design of Tumbling Mill Lifter Bars Utilizing the Discrete Element MethodWilke DN; Govender N; Rajamani R; Pizette PAdvances in Structural and Multidisciplinary Optimizationbook contribution
2017Impact of drug shape on biological effects in the lungZellnitz S; Zellnitz L; Roblegg E; Fröhlich EDDL2017; Edinburgh (UK)poster presentation
2017Continuous-Flow Synthesis of Key Intermediates for the Preparation of a Novel Alzheimer APIZnidar, D; Cantillo, D; Inglesby, P; Boyd, A; Kappe, CO6th Conference on Frontiers in Organic Synthesis Technology, Budapest, Hungaryposter presentation
2017Integration of Bromine and Cyanogen Bromide Generators for the Telescoped Continuous Synthesis of Cyclic GuanidinesGlotz G; Lebl R; Dallinger C; Kappe COAngewandte Chemie International Editionpaper refereed
2017Drug–excipient interactions in the solid state: The role of different stress factorsGressl C; Brunsteiner M; Davis A; Landis M; Pencheva K; Scrivens G; Sluggett G; Wood G; Gruber-Woelfler H; Khinast J, Paudel AMolecular Pharmaceuticspaper refereed
2017Advances in experimental and mechanistic computational models to understand pulmonary exposure to inhaled drugsBäckman P; Arora S; Couet W; Forbes B; de Kruijf W; Paudel AEuropean Journal of Pharmaceutical Sciencespaper refereed
2017Crystal Engineering in Continuous Plug-Flow CrystallizersBesenhard M; Neugebauer P; Scheibelhofer O; Khinast JGCrystal Growth and Designpaper refereed
2017Polyhedral Particles in DEMSiegmann EAIChE Annual Meeting 2017, Minneapolis (US)oral presentation
2017Simulating convex polyhedral particles utilizing the discrete element method on GPUSiegmann EAIChE Annual Meeting 2017, Minneapolis (US)oral presentation
2017Merck GEA Tablet Coater - Heat Transfer ModelBöhling PAIChE Annual Meeting 2017, Minneapolis (US)oral presentation
2017Debiopharm 1D HME code validation Itrakonazole+IbuprofenMatic JAIChE Annual Meeting 2017, Minneapolis (US)oral presentation
2017Long-term coating predictions for a Wurster fluidized-bed coater using a combined CFD-DEM and Markov-chain Monte Carlo approachToson PAIChE Annual Meeting 2017, Minneapolis (US)oral presentation
2017Utilization of Fluoroform for Difluoromethylation in Continuous Flow: A Concise Synthesis of α-Difluoromethylamino AcidsKöckinger M; Ciaglia T; Bersier M; Hanselmann P; Gutmann G; Kappe COGreen Chemistrypaper refereed
2017Impact of the pulmonary deposition and in vitro permeability on the prediction of plasma levels of inhaled budesonide formulationSalar-Behzadi S; Wu S; Mercuri A; Meindl C; Stranzinger S; Fröhlich EInt J pharmpaper refereed
2017Rational design of ethylene-vinyl acetate based reservoir type systems comprising estradiolKoutsamanis I; Eder S; Mohr S; Paudel A; Witschnigg A; Roblegg EPBP World Meeting 2018poster presentation
2017Continuous Drying of PharmaceuticalsKreimer M; Aigner S; Sacher S; Krumme M; Mannschott T; van der Wel P; Kaptein A; Khinast JGAIChE Annual Meeting 2017, Minneapolis (US)oral presentation
2017Application of Advanced Process Control Tools in Continuous ProcessingSacher S; Rehrl J; Kruisz J; Scheibelhofer O; Aigner I; Martinetz M; Wahl P; Khinast JGAIChE Annual Meeting 2017, Minneapolis (US)oral presentation
20172D Printed Product Design of Patient Centric Dosage Forms for Adaptive Clinical TrialsLopes D; Hsiao WK; Wimmer-Teubenbacher M; Wutscher T; Paudel A; Bresciani M; Ghiotti P; Eeckman F; Khinast JAIChE Annual Meeting 2017, Minneapolis (US)oral presentation
2017Investigation of Microsphere Strength for Spray Drying Applications by Means of Acoustic LevitationKreimer M; Aigner S; Sacher S; Krumme M; Mannschott T; van der Wel P; Kaptein A; Schröttner H; Brenn G; Khinast JGAIChE Annual Meeting 2017, Minneapolis (US)oral presentation
2017Optimization of a Low-dose Dosator Capsule Filling Process for Dry Powder Inhalation (DPI) Applications using In-line PAT ApproachesStranzinger S; Faulhammer E; Scheibelhofer O; Calzolari V; Biserni S; Paudel A; Khinast JG17th American Institute of Chemical Engineers (AIChE) Annual Meeting 2017. Minneapolis (US)oral presentation
2017Mechanical strength of microspheres produced by drying of acoustically levitated suspension dropletsKreimer M; Aigner I; Sacher S; Krumme M; Mannschott T; van
der Wel P; Kaptein A; Schroettner H; Brenn G; Khinast JG
Powder Technologypaper refereed
2017Flow Chemistry for Gas-Liquid TransformationsHone CUK Automated Synthesis Forum 2017; Northhampton (UK)oral presentation
2017Design and 3D printing of a stainless steel reactor for continuous difluoromethylations using fluoroformGutmann B; Köckinger M; Glotz G; Ciaglia T; Slama E; Zadravec M; Pfanner S; Maier MC; Gruber-Wölfler H; Kappe COReaction Chemistry and Engineeringpaper refereed
2017Design Space Prediction for Roller Compaction Processes Using a Model Based ApproachToson PAAPS Annual Meeting 2017; San Diego (USA)poster presentation
2017Impulse-Based Dynamics for Studying Quasi-static Granular Flows: Application to Hopper Emptying of Non-spherical ParticlesToson PAAPS Annual Meeting 2017; San Diego (USA)poster presentation
2017Design and 3D Printing of a Stainless Steel Reactor for Continuous Difluoromethylations Using Fluoroform Gutmann B; Köckinger M; Glotz G; Ciaglia T; Slama E; Zadravec M; Pfanner S; Maier MC; Gruber-Wölfler H; Kappe CO9th Symposium on Continuous Flow Reactor Technology for Industrial Applications; Barcelona (ES)poster presentation
2017On-Demand On-Site Continuous Processing – The Concept of “Chemical Generators” in Modern Fine Chemical ManufacturingGutmann B; Cantillo D; Dallinger D; Glotz G; Mata A; Kappe CO9th Symposium on Continuous Flow Reactor Technology for Industrial Applications; Barcelona (ES)poster presentation
2017Continuous Flow Synthesis of an Agrochemical Intermediate via a Telescoped Nitration/ Hydrogenation/Cyclization SequenceCantillo D; Wolf B; Goetz R; Kappe CO9th Symposium on Continuous Flow Reactor Technology for Industrial Applications; Barcelona (ES)poster presentation
2017On-Demand On-Site Continuous Processing – The Concept of “Chemical Generators” in Modern Fine Chemical ManufacturingGutmann B; Cantillo D; Dallinger D; Glotz G; Mata A; Kappe CO9th Symposium on Continuous Flow Reactor Technology for Industrial Applications; Barcelona (ES)oral presentation
2017Preparation of personalized oral films containing 3 APIs for pain therapy in oncologyWimmer-Teubenbacher M; Lopes D; Hsiao WK; Paudel A; Khinast JG; Stegemann SAAPS Annual Meeting 2017; San Diego (USA)poster presentation
2017Continuous Flow Multistep Synthesis of α-Functionalized Esters via Lithium Enolate Intermediatesvon Keutz T; Strauss FJ; Cantillo D; Kappe COTetrahedron Letterspaper refereed
2017On-Demand On-site Continuous Processing – The Concept of “ChemicalGenerators” in Modern and Pharmaceutical and Fine Chemical ManufacturingGutmann BHazardous Chemistry for Streamlined Large Scale Synthesis; Antwerp (BE)oral presentation
2017Designing Optimal Formulations for Hot-Melt CoatingLopes DG; Zimmer A; Salar-Behzadi SInternational Journal of Pharmaceuticspaper refereed
2017Continuous solvent exchange washing of pharmaceutical intermediatesKreimer M; Aigner S; Sacher S; Krumme M; Mannschott T; van der Wel P; Kaptein A; Khinast JGAIChE Annual Meeting 2017, Minneapolis (US)poster presentation
2017Design Space Prediction for Roller Compaction Processes Using a Model Based ApproachPaus R; Jans E; Samanta A; Kumar A; Van Den Heuvel C; Geens J; Van Assche I; Lopes D; Toson P; Hsiao WK; Khinast J; Stibale S; Quodbach J; Kleinebudde PAAPS Annual Meeting 2017; San Diego (USA)poster presentation
2017Nebulized coenzyme Q10 nanosuspensions: A versatile approach for pulmonary antioxidant therapyRossi I; Sonvico F; McConville JT; Rossi F; Fröhlich E; Zellnitz S; Rossi A; Del Flavero E; Bettini R; Buttini FEuropean Journal of Pharmaceutical Sciencepaper refereed
2017Investigation of Agglomeration Strength of Single MicrospheresKreimer M; Aigner I; Sacher S; Krumme M; Mannschott T; van der We P; Kaptein A; Schröttner H; Brenn G; Khinast JDECHEMA (Jahrestreffen der ProcessNet-Fachgruppen "Agglomeration und Schüttguttechnik" und "Zerkleinern und Klassieren" )oral presentation
2017Performance indicators for carrier based DPIs: Carrier surface properties for capsule filling and API properties for in vitro aerosolisationFaulhammer E; Zellnitz S; Wutscher T; Stranzinger S; Zimmer A; Paudel AInternational Journal of Pharmaceuticspaper refereed
2017Characterization of the coating and tablet core roughness by means of 3D optical coherence tomographyMarkl D; Wahl P; Pichler H; Sacher S; Khinast JGInternational Journal of Pharmaceuticspaper refereed
2017Investigation of Single-Droplet Drying Kinetics in an Acoustic Levitator, Micro-Sphere Morphology and Mechanical Properties of Pharmaceutical Excipients Manuel Kreimer, Isabella Aigner, Stephan Sacher, Markus Krumme, Thomas Mannschott, Peter van der Wel, Albert Kaptein, Hartmuth Schröttner, Günter Brenn, Johannes Khinast8th World Congress on Particle Technologyoral presentation
2017Investigation of Different Continuous Drying Routes for PharmaceuticalsManuel Kreimer, Isabella Aigner, Stephan Sacher, Markus Krumme, Thomas Mannschott, Peter van der Wel, Albert Kaptein, Johannes Khinast8th World Congress on Particle Technologyoral presentation
2017The Use of Continuous Processing in Organic SynthesisHone CFlow Forum 2017; Copenhagen (DK)oral presentation
2017Industrial Inkjet Printing for On-Demand Manufacturing of Film-in-Capsule Dosage FormsLopes D; Hauser L; Wutscher T; Paudel A; Hsiao WK; Bresciani M; Khinast J; Zimmer APBP World Meetingoral presentation
2017A Model-Based Approach to Scale Up Pharmaceutical Roller Compaction Processes for Continuous Manufacturing Raphael Paus, Eugeen Jans, Asim Samanta, Ashish Kumar, Bart Nitert, Jeroen Geens, Peter Toson, Diogo Lopes, Hsiao Wen Kai, Johannes Khinast, Sandy Stibale, Julian Quodbach, Peter KleinebuddePBP World Meeting 2018Oral Presentation
2017Impact of salbutamol sulphate particle properties on the tribocharging of inhalable mixtures Pinto JT; Zellnitz S; Roblegg E; Paudel ADDL2017; Edinburgh (UK)poster presentation
2017Evaluation of crystalline lactose-PEG composite particles as potential carriers for DPI formulationsPinto JT; Zellnitz S; Guidi T; De Smet L; Roblegg E; Paudel ADDL2017; Edinburgh (UK)poster presentation
2017Insights into development of a carrier based DPI – a particle engineering perspectivePinto JT; Zellnitz S; Roblegg E; Paudel APBP World Meeting 2018oral presentation
2016Investigation of extent and variability of vaginal delivery of ethinyl estradiol and etonogestrel from NuvaRing in healthy women compared to in vitro releaseNickisch K; Friedrich M; Warnke GA; Donath F; Schug B; Eggenreich K; Mohr S; Schrank Spaper refereed
2016Advanced stable lipid-based formulations for a patient-centric productBecker K; Saurugger E; Kienberger D; Lopes D; Haack D; Köberle M; Stehr M; Lochmann D; Zimmer A; Salar-Behzadi SInternational Journal of Pharmaceuticspaper refereed
2016A Multivariate Process Monitoring and Control Concept for a Small-Scale Fermenter in a PAT EnvironmentBesenhard M; Scheibelhofer O; François K; Joksch M; Kavsek BJournal of Intelligent Manufacturingpaper refereed
2016Continous Low-dose Feeding of Highly Active APIs in Hot-Melt ExtrusionLlusa M; Mohr S; Baumgartner R; Paudel A; Koscher G; Khinast J.GDrug Development and Industrial Pharmacypaper refereed
2016Continuous Manufacturing – ECCPM StatusKhinast JGECCPM Workshop 2016, Graz (AT)oral presentation
2016Having Fun with High Energy Nitrogen Compounds in FlowGutmann B; Kappe COFlow Chemistry Europe 2016; Cambridge (UK)oral presentation
2016Accelerating Multistep Kinetic Model Generation using Continuous Flow ReactorsHone C.A; Kappe C.OFlow Chemistry Europe 2016; Cambridge (UK)oral presentation
2016Comparing Particle Size Distributions of an Arbitrary Shape Powder TechnologyScheibelhofer O; Besenhard M; Piller M; Khinast J.GPowder Technologypaper refereed
2016An in vitro-in vivo correlation study for nifedipine immediate release capsules administered with water alcoholic and non-alcoholic beverages: impact of in vitro dissolution media and hydrodynamicsMercuri A; Fares R; Brescani M; Fotaki NInternational Journal of Pharmaceuticspaper refereed
2016Scale-Up of an HME Process Supported by 3D SPH and 1D Mechanistic ModellingMatic JProcessNet Jahrestagung; Bingen (DE)oral presentation
2016Nanex: Process design and optimizationBaumgartner RInternational Journal of Pharmaceuticspaper refereed
2016Development of an Abuse- and Alcohol-Resistant Formulation Based on Hot-Melt Extrusion and Film CoatinJedinger N; Schrank S; Fisher J.M; Breinhälter K; Khinast J.G; Roblegg EAAPS PharmSciTechpaper refereed
2016Comparing Particle Size Distributions of an Arbitrary ShapeMaximilian Besenhard Powder Technologypaper refereed
2016Simulation of an Tablet-Coating Process on the Industrial Scale
Modelling
Boehling P; Khinast J.GProcessNet Jahrestagung; Bingen (DE)oral presentation
2016Monitoring of a Hot-Melt Coating Process via a Novel Multipoint Near-Infrared SpectrometerHohl R; Scheibelhofer O; Stocker E; Salar-Behzadi S; Haack D; Lochmann D; Kerschhaggl P; Koch K; Sacher S; Zimmer AAAPS PharmSciTechpaper refereed
2016Monitoring of a Hot Melt Coating Process via a Novel Multipoint Near-Infrared SpectrometerHohl R; Scheibelhofer O; Stocker E; Behzadi S; Haack D; Koch K; Kerschnaggl P; Lochmann D; Sacher S; Zimmer AAAPS Pharm SciTechpaper refereed
2016Scale Up of a Tablet Coating Process Using the Discrete Element MethodBoehling P; Toschkoff G; Just S; Funke A; Djuric D; Knop K; Kleinebudde P; Khinast J.GLEK Workshop on Scale up of technological processesoral presentation
2016Modelling of Fluidized Bed GranulationPatsaki NCFDEM Workshop 2016; Linz (AT)oral presentation
2016The effect of model details on prediction of spray particles interaction in fluidized bedAskarishahi MCFDEM Workshop 2016; Linz (AT)oral presentation
2016Combining dry granulation and hot-melt coating for a patient centric medicine of ibuprofen sodiumLopes D Haack D Lochmann D Zimmer A Salar-Behzadi SPBP 2016poster presentation
2016Light in Powder - Penetration and InformationScheibelhofer O; Wahl P; Larchevêque B; Khinast JAIChE Annual Meeting 2016, San Francisco (US)poster presentation
2016Vacuum assisted flow initiation in arching powdersBaserina R; Sinka C; Rajniak RPowder Technologypaper refereed
2016NIR-Hyperspectral Imaging and Raman Chemical Mapping of Multilayer-TabletsPoms J; Scheibelhofer O; Sacher S; Khinast J.GMinisymposium Verfahrenstechnik 2016; Graz (AT)poster presentation
2016NIR-based Real Time Release Testing of Printed Orodispersible FilmsWimmer-Teubenbacher M. Pichler H. Kerschhaggl M. Planchette C. Gruber -Wölfler H. Hsiao W.K. Paudel A. Khinast J. Stegemann S.Minisymposium 2016; Graz (AT)poster presentation
2016CFD-DEM Simulation at wet fluidized bed: everporation rate from the spray and the particle surfaceAskarishahi MMinisymposium Verfahrenstechnik 2016; Graz (AT)poster presentation
2016Decoupling of a low-dose dosator capsule filling process in dynamic and static mode testsStranzinger S; Faulhammer E; Srčič S Dreu R; Biserni S; Calzolari V; Paudel A; Khinast JG3rd Austrian Particle Forum (APF) 2016. Graz (AT)Oral presentation
2016Feasibility study for turret speed operating points in a rotary tablet pressMartinetz M; Aigner I; Rehrl J; Scheiblhofer O; Laske S; Khinast J.GMinisymposium Verfahrenstechnik 2016; Graz (AT)oral presentation
2016Continuous Melt Extrusion And Direct PelletizationLaske S; Hörmann T; Witschnigg A; Koscher G; Wahl P; Hsiao WK; Khinast JGContinuous Manufacturing of Pharmaceuticalsbook contribution
2016Post Process Controlling of Printed ODF with Non-destructive MethodsWimmer-Teubenbacher M Pichler H Kerschhaggl M Markl D Planchette C Gruber-Wölfler H Hsiao WK Paudel A Khinast J Stegemann SPBP World MeetingOral presentation
2016Continuous manufacturing - Critical steps and possible solutionsKhinast JGPPB World Meeting Glasgow (UK)oral presentation
2016Micro dosing and Feeding via aVibratory sieve-chute systemBesenhard MPARTEC 2016; Nuremberg (DE)oral presentation
2016Investigation of Segregation Effects During Pharmaceutical TabletingSacher S; Wahl P; Llusa M; Khinast J.GPARTEC 2016; Nuremberg (DE)poster presentation
2016Particle-Based Modelling of Free-Surface Flow and Distributive Mixing in Modular Co-Rotating Twin-Screw ExtrudersMatic JPARTEC 2016; Nuremberg (DE)oral presentation
2016A Combined DEM & FEM Modelling of powder flow and compaction during roll pressingOrefice LPARTEC 2016; Nuremberg (DE)oral presentation
2016Optimization of a Micro-Feeding Unit in a Continuous Pharmaceutical Process LineHörmann T; Tausendschön J; Schmid T; Koscher G; Khinast J.GPARTEC 2016; Nuremberg (DE)poster presentation
2016Vacuum Compression Molding as Tool for Formulation ScreeningTreffer D; Hörmann T; Koscher G; Khinast J.GPARTEC 2016; Nuremberg (DE)poster presentation
2016Microdosing and feeding via avibratory sieve-chute systemFaulhammer E; Besenhard M; Khinast J; Calzolari V; Biserni SPARTEC 2016; Nuremberg (DE)Oral presentation
2016Tailoring interparticle interactions and drug detachment by using surface modified glass beads as model carrier particles in dry powder inhalersZellnitz S; Schroettner H; Urbanetz NA; Paudel APARTEC 2016; Nuremberg (DE)poster presentation
2016Evaluation of new engineered lactose particles as potential DPI carriersZellnitz S; Pinto J; Stranzinger S; Paudel AAIChE Annual Meeting 2016, San Francisco (US)Oral presentation
2016Continuous Manufacturing of Solid Dosage Forms: Development of a Novel Processing LineSacher S; Aigner I; Wahl P; Kleinebudde P; Rehbaum H; Khinast J.GPARTEC 2016; Nuremberg (DE)oral presentation
2016Development of a Model-Based Control Concept for a Direct Compaction Process Kruisz J; Rehrl J; Martinetz M; Sacher S; Horn M; Khinast J.GPARTEC 2016; Nuremberg (DE)poster presentation
2016Continuous Manufacturing of Solid Dosage Forms: Development of a Novel Processing LineSacher S; Aigner I; Wahl P; Kleinebudde P; Rehbaum H; Khinast J.GPartec 2016; Nürnberg (GE)proceedings
2016Optical Coherence Tomography for the Characterization of Pharmaceutical Film CoatingsMarkl D; Herzog A; Sacher S; Khinast J.GPARTEC 2016; Nuremberg (DE)oral presentation
2016Adsorption equilibrium modelling for different temperature conditions and its influence on adsorption mass transferZadravec MAnali PAZUpaper refereed
2016Modelling tumour cell proliferation from vascular structure using tissue decomposition into avascular elements Besenhard M; Jarzabek M; O'Farrell A; Callanan J.J; Prehn J; Byrne A; Huber HJournal of Theoretical Biology paper refereed
2016Lyophilized Protein Powders: A Review of Analytical Tools for Root Cause Analysis of Lot-to-Lot Variability Article referenceWahl V; Khinast JG; Paudel ATrends in Analytical Chemistrypaper refereed
2016Batch and Continuous Flow Aerobic Oxidation of 14-Hydroxy Opioids to 1,3-Oxazolidines - A Concise Synthesis of NoroxymorphoneGutmann B; Weigl U; Cox D.P; Kappe C.OChemistry- A European Journalpaper refereed
2016In-Line Monitoring of a Pharmaceutical Coating Process by Optical Coherence TomographySacher SSoitra PAT Workshop; Milan (IT)oral presentation
2016Continuous Feeding of Low-Dose APIs via Periodic Micro DosingBesenhard M; Karkala S; Faulhammer E; Fathollahi S; Ramachandran R; Khinast JGInternational Journal of Pharmaceuticspaper refereed
2016Injection Molding as a One-Step Process for the Direct Production of Pharmaceutical Dosage Forms from Primary PowdersEggenreich K; Windhab S; Schrank S; Treffer D; Juster H; Steinbichler G; Laske S; Koscher G; Roblegg E; Khinast J.GInternational Journal Pharmaceuticspaper refereed
2016LifeCycle Risikomanagement -Modell des objektorientierten Risikomanagements zur praxisgerechten Umsetzung des Qualitätsrisikomanagements über den Produktlebenszyklus von Arzneimitteln und MedizinproduktenGübitz B; Khinast J.Gpharmindpaper refereed
2016Effect of bubble-particle interaction models on flow predictions in three-phase bubble colmunsGruber MC; Radl S; Khinast JGChemical Engineering Sciencepaper refereed
2016Liquid Transfer between solid particles Patsaki NECCOMAS 2016; Crete Island (GR)oral presentation
2016Coupled CFD/DEM Muttiphase Simulation of a bottom Spray Wurster Cooter using a hybrid CPU/GPU approachZadravec MECCOMAS 2016; Crete Island (GR)oral presentation
2016Irregular shaped particles for DEM high performance algorithmusSiegmann EECCOMAS 2016; Crete Island (GR)oral presentation
2016Scale Down of a Production Scale Tablet Coating ProcessBoehling PECCOMAS 2016; Crete Island (GR)oral presentation
2016Study of Particles back flow in partially filled screw feeder conveyorsOrefice LECCOMAS 2016; Crete Island (GR)oral presentation
2016SPH Simulation of a TransferboxKondor ISPHERIC 2016; Munich (DE)oral presentation
2016Conformational flexibility related to enzyme activity: evidence for a dynamic active-site gatekeeper function of Tyr 215 in Aerococcus viridans lactate oxidaseStoisser T; Brunsteiner M; Wilson DK; Nidetzky BScientific Reportspaper refereed
2016Improving the granule strength of roller compacted ibuprofen sodium for hot-melt coating processingLopes DG; Garsuch V; Becker K; Paudel A; Stehr M; Zimmer A; Salar-Behzadi SInternational Journal of Pharmaceuticspaper refereed
2016Measurements of deposition lung surface area and lung fluid for simulation of inhaled compoundsFröhlich E; Mercuri A; Wu S; Salar-Behzadi SFrontiers in Pharmacologypaper refereed
2016Laboratory-Scale Membrane Reactor for the Generation of Anhydrous DiazomethaneDallinger D; Pinho V.D; Gutmann B; Kappe C.OJournal of Organic Chemistrypaper refereed
2016An Overview of Pharmaceutical Manufacturing for Solid Dosage FormsSacher S; Khinast J.GHumana Press; Springerbook contribution
2016The Plug & Play Reactor: A Highly Flexible Device for Heterogeneous Reactions in Continuous Flow ModeGruber-Wölfler H, Lichtenegger G, Kitzler H, Obermaier K, Khinast JGChemie Ingenieur Technikpaper refereed
2016Continuous Flow Generation and Use of Chlorine for Organic SynthesisStrauss F; Cantillo D; Kappe C.OESS-HPT 2016 The European Summer School in High Pressure Technologyoral presentation
2016Challenges of process analysis in continuous manufacturingScheibelhofer OINDATECH Customer Conference - Optimization of Process Dev and Manufacturing for Pharma and Biotechoral presentation
2016Morphological changes of inkjet printed sodium picosulfateWimmer-Teubenbacher M; Pichler H; Markl D; Peter A; Hsiao W.K; Paudel A; Khinast J.G; Stegemann SPSSRC Annual Meeting 2016; Copenhagen (DK)oral presentation
2016Efficient DEM-simulations of large-scale mixing processesSiegmann EPSSRC 2016; Copenhagen (DK)oral presentation
2016Characterization of salbutamol sulphate powders after secondary processing - impact on aerosolisationPinto JT; Radivojev S; Zellnitz S; Paudel A; Khinast J.G; Roblegg EPSSRC 2016; Copenhagen (DK)oral presentation
2016Toward the Synthesis of Noroxymorphone via Aerobic Palladium-Catalyzed Continuous Flow N-Demethylation StrategiesGutmann B; Elsner P; Cox DP; Weigl U; Roberge D; Kappe C.OACS Sustainable Chemistry and Engineeringpaper refereed
2016Pore blocking: an innovative strategy for the design of alcohol resistant multiparticulatedosage formsSchrank S; Jedinger N; Wu S; Piller M; Roblegg EInternational Journal of Pharmaceuticspaper refereed
2016Impact of particle engineering on the processability and aerosolisation of DPI formulationsZellnitz S; Faulhammer E; Wutscher T; Paudel A; Khinast J.KDDL 27 2016poster presentation
2016The effect of material attributes and process parameters on the powder bed uniformity during a low-dose dosator capsule filling processStranzinger S; Faulhammer E; Srčič S Dreu R; Biserni S; Calzolari V; Paudel A; Khinast JG10th Annual Meeting of the Pharmaceutical Solid State Research Cluster (PSSRC) 2016. Copenhagen (DK)Oral presentation
2016In Vitro Characteristics and Mechanical Properties of Polymer Based Long-Acting Intravaginal Drug Delivery SystemsEggenreich K; Schrank S; Koscher G; Roblegg E; Khinast JPPS 2016; Lyon (FR)oral presentation
2016Influence of Process Route on the Mechanical Properties of Polymer Based Intravaginal Drug Delivery SystemsEggenreich K; Schrank S; Koscher G; Nickisch K; Roblegg E; Khinast JPPS 2016 Lyonpaper refereed
2016Drug–excipient degradation in the solid state: Computational and experimental approachesGressl C; Brunsteiner M; Paudel A; Davis A; Landis M; Pencheva K; Scrivens G; Sluggett G.W; Wood; G.P.F; Khinast J.GPSSRC 2016; Copenhagen (DK)oral presentation
2016Solid-State Reactivity of Drugs with Potential Reactive Excipient Impurities: In silico and Experimental Studies Gressl C; Brunsteiner M; Davis AM; Landis K; Pencheva G; Scrivens GW; Sluggett GPF; Wood A; Paudel A; Khinast JGAIChE Annual Meeting 2016, San Francisco (US)poster presentation
2016Comparing and Contrasting the Solid-State Esterification of APIs with Excipient: Computational and Experimental AssessmentGressl C; Brunsteiner M; Davis AM; Landis K; Pencheva G; Scrivens GW; Sluggett GPF; Wood A; Paudel A; Khinast JGAIChE Annual Meeting 2016, San Francisco (US)poster presentation
2016An in-vitro and in-silico study of the impact of engineered surface modifications on drug detachment from model carriersMercuri A; Wu S; Zellnitz S; Salar-Behzadi S; Bresciani M; Fröhlich EInternational Journal of Pharmaceuticspaper refereed
2016A Laboratory-Scale Continuous Flow Chlorine Generator for Organic Synthesis Strauss F; Cantillo D; Guerra J; Kappe C.OReaction Chemistry and Engineeringpaper refereed
2016Optimized continuous pharmaceutical manufacturing via model-predictive controlRehrl J; Kruisz J; Sacher S; Khinast J.G; Horn MInternational Journal of Pharmaceuticspaper refereed
2016Micro-feeding and dosing of powders via a small-scale powder pumpBesenhard M; Fathollahi S; Siegmann E; Slama E; Faulhammer E; Khinast J.GInternational Journal of Pharmaceuticspaper refereed
2016Hot Melt Coating for QbD Oriented Patient-Centric Product Development: An OverviewSalar-Behzadi S; Lopes D; Becker K; Hohl R; Stehr M; Lochmann D; Haack D; Bresciani M; Khinast JG; Zimmer ACHISA 2016; Prag (CZ)oral presentation
2016Rational Approaches to the Development of Advanced Pharmaceutical Manufacturing SystemsKhinast JG9th Swiss Pharma Science Day 2016 , BERN (CH)oral presentation
2016The drying of particle-laden pastesBrenn G; Steiner H; Kondor I; Planchette C; Mercuri A; Scharrer GInternational Journal of Heat Mass Transferpaper refereed
2016The effect of different gaps between the dosator tip and the bottom of the powder bed container on the fill weight and weight variability of a low-dose capsule filling processStranzinger S; Faulhammer E; Srčič S; Dreu R; Biserni S; Calzolari V; Paudel A; Khinast J.G7th International Congress on Pharmaceutical Engineering (ICPE) 2016. Graz (AT)poster presentation
2016Continuous-Flow Electrophilic Amination of Arenes and Schmidt Reaction of Carboxylic Acids Utilizing the Superacidic Trimethylsilyl Azide/Triflic Acid Reagent SystemChen Y; Gutmann B; Kappe O.CJournal of Organic Chemistrypaper refereed
2016Taste-masking of multiparticulate dosage formsZimmer A; Becker K; Lopes D; Haack D; Lochmann D; Salar-Behzadi S11th Central European Symposium on Pharmaceutical Technology Belgrad 22nd-24th September 2016oral presentation
2016Multi-methodological Investigation of the Variability of the Microstructure of HPMC Hard CapsulesFaulhammer E; Kovalcik A; Wahl V; Markl D; Stelzer F; Lawrence S; Khinast JG; Paudel AInternational Journal of Pharmaceuticspaper refereed
2016DEM study of granular transport in partially filled horizontal screw conveyorsOrefice L, Khinast JGElsevier Powder Technologypaper refereed
2016Evaluation of the Tablets' Surface Flow Velocities in Pan CoatersDreu R; Toschkoff G; Funke A; Altmeyer A; Knop K; Khinast J; Kleinebudde PEuropean Journal of Pharmaceutical and Biopharmaceuticalspaper refereed
2016Local Gas Holdup Simulation and Validation of Industrial-scale Aerated BioreactorsWitz C; Treffer D; Hardiman T; Khinast J.GChemical Engineering Science paper refereed
2016Continuous Manufacturing of Solid Dosage Forms: Development of a Control Strategy for an Integrated Processing LineSacher S; Aigner I; Wahl P; Khinast J.GEuPAT8; Cork (IR)oral presentation
2016Continuous Manufacturing of Solid Dosage Forms: Development of a Control Strategy for an Integrated Processing LineSacher S; Aigner I; Wahl P; Khinast J.GEuPAT8; Cork (IR)poster presentation
2016Continuous Quality Control of Tablets via NIR Chemical Imaging and Optical Coherence TomographySacher S; Wahl P; Khinast JGEuPAT8; Cork (IR)oral presentation
2016Continuous Quality Control of Tablets via NIR Chemical Imaging and Optical Coherence TomographySacher S; Wahl P; Khinast J.GEuPAT8; Cork (IR)poster presentation
2016Speed change experiments in a rotary tablet pressMartinetz M; Sacher S; Khinast JEuPAT8; Cork (IR)poster presentation
2016Simulation of a Tablet Coating Process at Different Scales using DEM European Journal of Pharmaceutical SciencesBoehling P; Toschkoff G; Dreu R; Just S; Knop K; Kleinebudde P; Funke A; Rehbaum H; Rajniak P; Khinast J.KEuropean Journal of Pharmaceutical Sciencespaper refereed
2016Development and evaluation of accelerated drug release testing methods for a matrix-type intravaginal ringExternbrink A; Eggenreich K; Schrank S; Mohr S; Nickisch K; Klein SEuropean Journal of Pharmaceuticspaper refereed
2016Two step validation process of particle mixing in a centrifugal mixer with vertical axisZadravec MJournal of Process Mechanical Engineeringpaper refereed
2016Applying ICH Q9 quality risk management tools for advanced development of pharmaceutical hot melt coated multiparticulate systemsStocker E; Becker K; Hate S; Hohl R; Schiemenz W; Sacher S; Khinast J.G; Salar-Behzadi SJournal of Pharmaceutical Sciencespaper refereed
2016DNS Simulation of Liquid Transfer Between Patsaki N2016 Annual Meeting; San Francisco (USA)oral presentation
2016Efficient DEM-simulation of granular mixing behavior for large-scale applicationsSiegmann EAIChE Annual Meeting 2016, San Francisco (US)oral presentation
2016Comparison of Coupled CFD –DEM Simulation Results and TFM Simulation Results to Experimental Data in Laboratory Scale Wurster CoaterBöhling PAIChE Annual Meeting 2016, San Francisco (US)oral presentation
2016Scale-up of HME Process from a Trilobed 16mm to a Bilobed 27mm Extruder; SPH Simulations and 1D Mechanistic ModellingMatic J2016 Annual Meeting; San Francisco (USA)oral presentation
2016Process Development for continuous Extrusion and Pelletization of a Heat and Shear-Sensitive FormulationHörmann TR; Laske S; Koscher G; Khinast JGAIChE Annual Meeting 2016, San Francisco (US)poster presentation
2016Application of Model-Predictive Control to a Feeding Blending UnitRehrl J; Kruisz J; Sacher S; Horn M; Khinast JAIChE Annual Meeting 2016, San Francisco (US)poster presentation
2016Establishing a procedure of transferring HME processes using physical similaritiesWitschnigg A; Zagler M; Hörmann TR; Koscher G; Laske S; Khinast JGAIChE Annual Meeting 2016, San Francisco (US)oral presentation
2016Development of a Continuous Production Line for Solid Dosage Forms Via Dry GranulationAigner I; Sacher S; Kruisz J; Martinetz M; Wahl P; Khinast JAIChE Annual Meeting 2016, San Francisco (US)oral presentation
2016Real-Time Monitoring and Ejection of out-of-Spec Tablets Via NIR Chemical ImagingWolfgang M; Wahl P; Hauseder G; Sacher S; Kerschhaggl M; Khinast JGAIChE Annual Meeting 2016, San Francisco (US)poster presentation
2016Using Optical Coherence Tomography (OCT) to Analyze in Real-Time the Tablet Coating Variability of a Continuous Drum Coating ProcessWahl P; Zettl M; Wolfgang M; Sacher S; Bastian R; Fränkel T; Khinast JGAIChE Annual Meeting 2016, San Francisco (US)oral presentation
2016Continuous drying of powders and slurries in an extruder without changing product particle size distributionKreimer M; Aigner I; Koscher G; Lepek D; Khinast JGAIChE Annual Meeting 2016, San Francisco (US)oral presentation
2016Halogenation of organic compounds using continuous flow and microreactor technologyCantillo D; Kappe C.OReaction Chemistry and Engineeringpaper refereed
2016The Use of Molecular Oxygen in Pharmaceutical Manufacturing – Is Flow the Way to Go?Hone C; Roberge D; Kappe C.OChemSusChempaper refereed
2016Blaze DEM3D-GPU A Large Scale DEM simulation code for GPUsGovender N; Wilke D; Pizette P; Khinast JGPowders and Grains paper refereed
2016PAT strategies in secondary solid oral dosage manufacturing of small moleculesLaske S; Paudel A; Scheibelhofer OJournal of Pharmaceutical Sciences paper refereed
2016A Review of PAT Strategies in Secondary Solid Oral Dosage Manufacturing of Small MoleculesLaske S; Paudel A; Scheibelhofer OJournal of Pharmaceutical Sciencespaper refereed
2016Full-Physics Simulations of Spray-Particle Interaction in a Bubbling Fluidized BedAskarishahi MAIChE Journal paper refereed
2016Sensitivity Analysis of a Pharmaceutical Tablet Production Process from the Control Engineering PerspectiveRehrl J; Gruber A; Khinast J; Horn MInternational Journal of Pharmaceuticspaper refereed
2016Continuous Secondary Drying of Powders via ExtrusionKreimer M; Aigner S; Khinast J.GI2APM 2016; Glasgow (UK)poster presentation
2016Decoupling of a low-dose dosator capsule filling process in dynamic and static mode tests to understand the extend of the effect of powder and process parameters on capsule quality attributesFaulhammer E; Stranzinger S; Biserni S; Calzolari V; Khinast JAIChE Annual Meeting 2016, San Francisco (US)Oral presentation
2016The effect of particle engineering on the processing and the in vitro performance of inhalation blends in dry powder inhalers Faulhammer E; Wutscher T; Stranzinger S; Paudel AAIChE Annual Meeting 2016, San Francisco (US)poster presentation
2016Why Hot Melts Do Not Stick to Cold SurfacesTreffer D; Khinast J.GPolymer Engineering and Sciencepaper refereed
2016Continuous Flow Homolytic Aromatic Substitution with Electrophilic Radicals – A Fast and Scalable Protocol for TrifluoromethylationMonteiro J.L; Carneiro P.F; Elsner P; Roberge D.M; Wuts P.G.M; Kurjan K.C; Gutmann B; Kappe C.OChemistry- A European Journalpaper refereed
2016Industrial Scale Particle Simulations on the GPU Using the Blaze-DEM CodeGovender N; Wilke DN; Pizettec P; Abriak NEProceedings of the 7th International Conference on Discrete Element Methodsbook contribution
2016Analysis of Flow and Mixing in Screw Elements of Co-Rotating Twin-Screw Extruders via SPHEitzlmayer A; Matic J; Khinast J.GAichE Journalpaper refereed
2016Improving drug release and stability of solid lipid dosage formsZimmer A; Lopes D; Koutsamanis I; Becker K; Scheibelhofer O; Laggner P; Lochmann D; Haack D; Salar-Behzadi S2nd European Congress on Pharmaceutics, April 2017; Krakow (PL)oral presentation
2016Continuous Flow Synthesis of a Key 1,4-Benzoxazinone Intermediate via a Nitration/Hydrogenation/Cyclization SequenceCantillo D; Wolf B; Goetz R; Kappe C.OOrganic Process Research and Developmentpaper refereed
2016In vitro and in silico characterization of Tacrolimus released und Biorelevant conditionsMercuri A; Wu S; Stranzinger S; Mohr S; Salar-Behzadi S; Bresciani M; Fröhlich EInternational Journal of Pharmaceuticspaper refereed
2016Continuous monitoring of API content, API distribution and crushing strength after tableting via near-infrared chemical imagingWahl P.R.; Pucher I; Scheibelhofer O; Kerschhaggl M; Sacher S; Khinast J.GInternational Journal of Pharmaceuticspaper refereed
2015Combining Hot-melt coating with drug dry granulation for userfriendly solid oral dosage formsLopes D; Becker K;Haack D; Stehr M; Zimmer A; Salar-Behzadi SDocday KFUoral presentation
2015Evaluation of Parameter Estimation Methods for Crystallization Processes Modeled via Population Balance EquationsBesenhard M; Chaudhury A; Vetter T; Ramachandran R; Khinast J.GChemical Engineering Research and Designpaper refereed
2015In-line Monitoring of Segregation Effects in a Pharmaceutical Tableting ProcessSacher S; Wahl P; Scheibelhofer O; Hohl R; Khinast JGIFPAC 2015; Arlington (USA)oral presentation
2015Influence of residual water on the secondary structure and crystallinity of freeze-dried fibrinogenWahl V; Scheibelhofer O; Rössl U; Leitgeb S; deBeer T; Khinast J.GInternational Journal of Pharmaceuticspaper refereed
2015Moisture induced changes in secondary structure and crystallinity of human fibrinogen powdersWahl V Scheibelhofer O Roessl U Leitgeb S deBeer T Khinast JICAVSposter presentation
2015The effect of the drying temperature on the properties of wet-extruded calcium stearate pellets: pellet microstructure; drug distribution; solid state and drug Schrank S; Kann B; Saurugger E; Hainschitz M; Windbergs M; Glasser B.J; Khinast J.G; Roblegg EInternational Journal of Pharmaeuticspaper refereed
2015Co-rotating twin-screw extruders: detailed analysis of conveying elements based on smoothed particle hydrodynamics. Part II: mixingStocker E; Salar-Behzadi S; Hohl R; Sacher S; Khinast JGEuPAT 7, Graz (A)poster presentation
2015Polymeric formulations for drug release prepared by hot melt extrusion: applications and characterization- Review Stankovic M; Frijlink H.W; Hinrichs W.L.J Drug Discovery Todaypaper refereed
2015Automated pharmaceutical tablet coating layer evaluation of optical coherence tomography imagesMarkl D; Hannesschläger G; Sacher S; Leitner M; Khinast J.G; Buchsbaum AMeasurement Science and Technologypaper refereed
2015Total Surveillance! Inline Monitoring of Tablets via NIR Chemical ImagingWahl P; Scheibelhofer O; Sacher S; Khinast J.GIFPAC 2015; Arlington (USA)oral presentation
2015Dissolution of Tacrolimus from modified release formulations under biorelevant conditionsMercuri A; Sattler A; Stranzinger S; Wu S; Mohr S; Salar-Behzadi S; Froehlich EControlled release society (CRS) poster presentation
2015Inhalation ProductsMercuri A Fotaki NIn vitro Release Testing of Special Dosage Forms (Wiley-Blackwell UK)book contribution
2015Permeation of therapeutic drugs in different formulations across the airway epithelium in vitroMeindl C; Stranzinger S; Dzidic N; Salar-Behzadi S; Mohr S; Fröhlich EPlos onepaper refereed
2015Novel Vacuum Compression Molding as a Tool for Sample Preparation in Rotational Melt RheologyTreffer D; Troiss A; Khinast J.G24th Nordic Rheology Conference (FI)oral presentation
2015True-shape tablet simulationsat industrial scaleRadeke CParticle Simulations Conference; Erlangen (DE)oral presentation
2015Melt Rheology of Selected Pharmaceutical
Polymers for Hot Melt Extrusion
Treffer D; Troiss A; Khinast J.G24th Nordic Rheology Conference (FI)poster presentation
2015Micro Pelletizing of Pharmaceutical HME Formulations Using a Die Face PelletizerWitschnigg A; Koscher G; Muerb KR; Laske S; Treffer D; Khinast JPPSpaper refereed
2015A model for the non-isothermal drying of particle-laden pastesBrenn G; Steiner H; Kondor I; Planchette C; Mercuri A; Scharrer GInternational journal of heat and mass transferpaper refereed
2015Numerical Coating Simulations at industrial scale using non-spherical bi-konvex objectsRadeke CECS, Eindhoven oral presentation
2015True Shape Objects and Coating Capabilities for Industrial ApplicationsRadeke CAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015DEM model of infeed particle flow in Rolling CompactionOrefice LPARTEC 2015; Nürnberg (DE)oral presentation
2015Crystal SizeTuning in Continuous CrystallizersBesenhard MPARTEC 2015; Nürnberg (DE)oral presentation
2015Impact of carrier modification on the capsule filling processability and on aerosolization performance of carrier-based dry powder inhalation (DPI) formulationFaulhammer E; Wahl V; Zellnitz S; Khinast J; Paudel AEACposter presentation
2015Fully Coupled Multiphase Simulation of a bottom-spray Wurster Coater Siegmann ECoupled problems 2015; Venice (IT)oral presentation
2015Characterization of tablet core and coating roughness by means of Optical Coherence TomographyMarkl D; Sacher S; Pichler H; Rinner P; Khinast J.GAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015QbD in Continuous Manufacturing and BiopharmaceuticsMercuri A3rd Symposium in QbD; Leicester (UK)poster presentation
2015Designed Blending for Near Infrared CalibrationScheibelhofer O; Grabner B; Bondi R; Igne B; Sacher S; Khinast J.GPharmaceutics; Drug Delivery and Pharmaceutical Technologypaper refereed
2015Investigation of Segregation Effects via Multipoint NIR Monitoring and NIR Chemical ImagingSacher S; Wahl P; Hohl R; Khinast J.GEuPAT 7; Graz (AT)oral presentation
2015Flowsheet Modelling as a Tool for Plant-wide Control Strategy Development for Continuous ProcessesKruisz J; Rehrl J; Gruber A; Sacher S; Khinast J.GEuPAT 7; Graz (AT)oral presentation
2015In-line Monitoring of Pharmaceutical Pan Coating Process by Means of Optical Coherence TomographyMarkl D; Hannesschläger G; Sacher S; Leitner M; Pescod R; Buchsbaum A; Khinast J.GIFPAC 2015; Arlington (USA)oral presentation
2015In-line Monitoring of the Coating Growth During the Production of Film-Coated TabletsMarkl D; Hannesschläger G; Sacher S; Leitner M; Pescod R; Buchsbaum A; Khinast J.GOCT4NDT; Dresden (DE)oral presentation
2015Off-Line and in-line tablet core and coating roughness analysis by means of optical coherence tomography Markl D; Hannesschläger G; Sacher S; Buchsbaum A; Khinast J.GEuPAT 7; Graz (AT)oral presentation
2015In-Line Monitoring of a Pharmaceutical Pan Coating Process by Optical Coherence TomographyMarkl D; Hannesschläger G; Sacher S; Buchsbaum A; Khinast JJournal of Pharmaceutical Sciencespaper refereed
2015Co-rotating twin-screw extruders: detailed analysis of conveying elements based on smoothed particle hydrodynamics. Part I: hydrodynamicsEitzlmayr A; Khinast J.GChemical Engineering Sciencepaper refereed
2015Co-rotating twin-screw extruders - detailed analysis of conveying elements based on smoothed particle hydrodynamics. Part II: mixingEitzlmayr A; Khinast J.G Chemical Engineering Sciencepaper refereed
2015In-line monitoring of a pharmaceutical fluid-bed and pan coating process by Optical Coherence TomographyMarkl D; Sacher S; Khinast J.GAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015Crystal Size Control in a Continuous Tubular CrystallizerBesenhard M; Neugebauer P; Ho C; Khinast J.GCrystal Growth & Designpaper refereed
2015Influence of in vitro pulmonary permeability on in silico prediction of oral inhalation productsWu S; Mercuri A; Salar-Behzadi S; Bresciani M; Paudel A; Fröhlich E 24th ÖPhG Annual Conference (AT)Oral presentation
2015Taste masked formulations with advanced performanceBecker K; Lopes D; Haack D; Stehr M; Bresciani M; Khinast J; Zimmer A; Salar-Behzadi SÖPhGoral presentation
2015Prozessentwicklung zur Herstellung schmelzextrudierter pharmazeutischer ProdukteTreffer D; Hörmann T; Koscher G; Khinast J.G41. Deutsche Componundiertagung Prozessoptimierung an Compoundieranlagen; (GE)oral presentation
2015Prozessentwicklung zur Herstellung schmelzextrudierter pharmazeutischer ProdukteTreffer D; Hörmann T; Koscher G; Khinast J.G41. Deutsche Componundiertagung Prozessoptimierung an Compoundieranlagen; (GE)proceedings
2015Use Case HMEHörmann T; Wahl P; Gursch J; Laske S; Koscher G; Khinast J.GECCPM Workshop 2015; Graz (AT)oral presentation
2015Use Case HMEHörmann T; Wahl P; Gursch J; Laske S; Koscher G; Khinast J.GECCPM Workshop 2015; Graz (AT)poster presentation
2015Assesing Tablet Surface velocity in a Drum Coater with Reference to Result of Highspeed Video DataBoehling P9th Annual Symposium of Pharmaceutical Solid State Research Cluster PSSRC; Ghent (BE)oral presentation
2015News on Continuous Manufacturing and Process Analytic Technology Khinast J.GECCPM Workshop 2015; Graz (AT)oral presentation
2015Investigating the influence of temperature on the bonding mechanism during roll compaction of Ibuprofen Na 2H2OLopes D; Paudel A; Becker K; Haack D; Lochmann D; Zimmer A; Salar-Behzadi S;9th PSSRC Annual Symposium; Ghent (BE)Oral presentation
2015Vacuum Compression Molding for Rapid Sample Tablet Preparation for New Hot-melt Extrusion FormulationsTreffer D; Fiedler D; Rustige S; Khinast J.G9th PSSRC Annual Symposium; Ghent (BE)oral presentation
2015Evaluation of extractables and leachables from filter materials and their impact on protein formulationsWahl V Mohr S Münzer J Khinast J Paudel A9th PSSRC Annual Symposium; Ghent (BE)Oral presentation
2015Manufactoring of personalized medicineHsiao WK; Pichler H; Wimmer-Teubenbacher M; Pival S; Bresciani M; Roblegg E; Khinast JDiagnostics 5.0 Oral presentation
2015Modeling and simulation for optimization and control of secondary continuous pharmaceutical manufacturing processesKhinast J.G9th PSSRC Annual Symposium; Ghent (BE)oral presentation
2015Challenges and Solutions for DEM Simulations in the Pharmaceutical IndustryRadeke CParticle Simulations Conference; Erlangen (DE)oral presentation
2015The Potential of SPH for the Simulation of Fully and Partially Filled Co-Rotating Twin-Screw Extruder ElementsMatic JPPS 2015; Graz (AT)oral presentation
2015Chemically Treatment of Glass Surfaces to Reduce Alkali Ion Diffusion into Aqueous SolutionsGruber-Wölfler H; Schweiger S; Neubauer C Austrian Chemistry Days (AT)oral presentation
2015Novel Vacuum Compression Molding as a Tool for Sample Preparation in Rotational Melt RheologyTreffer D; Troiss A; Khinast J.GPPS 2015; Graz (AT)oral presentation
2015Melt Rheology of Selected Pharmaceutical PolymersTreffer D; Troiss A; Khinast J.GPPS 2015; Graz (AT)poster presentation
2015Keynote - Modeling and simulation for optimization and control of secondary continuous pharmaceutical manufacturing processesKhinast J.GCMAC Open Day 2015; Glasgow (UK)oral presentation
2015Development of Immediate-Release Tablets Processed via Hot-Melt ExtrusionHörmann T; Laske S; Koscher G; Khinast J.GPPS 2015; Graz (AT)oral presentation
2015Discrete Element Modelling of Liquid Transfer between Particles Patsaki NParticles 2015; Barcelona (ES)oral presentation
2015Multi-scale modeling of Spray DryingRajnak PParticles 2015; Barcelona (ES)oral presentation
2015Investigating the uniformity of an active coating process in the industrial scale using DEM simulationsBoehling PParticles 2015; Barcelona (ES)oral presentation
2015Multiphase Modeling and Large-Scale Simulations on GPU Platforms Khinast J.GISTP 26; Leoben (AT)oral presentation
2015Effect of a screw feeder induced flow in Rolling Compaction: a DEM modelOrefice LParticles 2015; Barcelona (ES)oral presentation
2015Role of Lipid Blooming and Crystallite Size in the Performance of Highly Soluble Drug Loaded MicrocapsulesLopes D; Becker K; Stehr M; Lochmann D; Haack D; Zimmer A; Salar- Behzadi SJournal of Pharmaceutical Sciencespaper refereed
2015Stability by design: Physical and chemical stability of different polymorphs of pharmaceutical solidsGressl C; Brunsteiner M; Paudel A; Khinast J.G; Davis A; Landis M; Pencheva K; Scrivens G; Sluggett G.W; Wood G.P.F9th PSSRC Annual Symposium; Ghent (BE)oral presentation
2015Crystallization kinetics of inhalable size amorphous salbutamol as a function of relative humidity and temperatureZellnitz S; Narygina O; Resch C; Schroettner H; Paudel AEACposter presentation
2015Understanding the In Vivo Impact of Carrier-Drug Inter Particle Forces Via Engineered Surface Modifications: An In Silicio InvestigationMercuri A; Wu S; Zellnitz S; Salar-Behzadi S; Bresciani M; Khinast J; Fröhlich EDDL26, Edinburgh 2015 (UK)poster presentation
2015Continuous Processing of Active Pharmaceutical Ingredients Suspensions via Dynamic Cross-Flow FiltrationGursch J; Hohl R; Toschkoff G; Dujmovic D; Brozio J; Krumme M; Rasenack N; Khinast J.GJournal of Pharmaceutical Sciencespaper refereed
2015Influence of Calu-3 permeability on in silicio pharmacokinteic prediction of inhalation productsWu S; Mercuri A; Salar-Behzadi S; Schiaretti F; Zambelli E; Brogin G; Govoni M; Meindl C; Stranzinger S; Mohr S; Dzidic N; Bresciani M; Fröhlich E DDL26, Edinburgh 2015 (UK)poster presentation
2015Dynamic cross-flow filtration: enhanced continuous small-scale solid-liquid separationGursch J; Hohl R; Dujmovic D; Brozio J; Krumme M; Rasenack N; Khinast J.GDrug Development and Industrial Pharmacypaper refereed
2015Multi-parameter flow cytometry as a process analytical technology (PAT) approach for the assessment of Bacterial Ghost productionLangemann T; Mayr U; Meitz A; Lubitz W; Herwig CAppl Microbiol Biotechnolpaper refereed
2015Impact of impeller design on high shear wet granulationBoerner M; Michaelis M; Siegmann E; Radeke C; Schmidt UPowder Technologypaper refereed
2015Low-dose dosator capsule filling for inhalation productsFaulhammer E; Llusa M; Paudel A; Lawrence S; Biserni S; Calzolari V; Khinast JMVIC - SwedenOral presentation
2015In vitro-in vivo correlation for nifedipin IR capsules: the impact of hydrodynamics and ethanolMercuri A Fares R Brescani M Fotaki NAAPSposter presentation
2015Printing medicines as orodispersible dosage forms: Effect of substrate on the printed micro-structurePlanchette C; Pichler H; Wimmer-Teubenbacher M; Gruber M; Gruber-Wölfler H; Mohr S; Tetyczka C; Hsiao W.K; Roblegg E; Khinast J.GInternational Journal of Pharmaceuticspaper refereed
2015Gluing Pills: A novell approach for processing of multi-layer tabletsSalar-Behzadi S; Stranzinger S; Lingitz J; Sacher S; Khinast JAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015Keynote - Innovation in Development and Research - Computer-Modeling Aided Generic DevelopmentKhinast J.GSandoz R&D Day 2015; (AT)oral presentation
2015The Future of Pharmaceutical Manufacturing SciencesRantanen J; Khinast J.GJournal of Pharmaceutical Sciencespaper refereed
2015Development of Mechanistic Model for Fluid Bed GranulationRajnak PAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015Simulation of an Tablet-Coating Process on Industrial Scale Boehling PAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015A novel approach to simulate large scale fluidized beds by CFD-DEM.Ebrahimi RAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015Scale-Up of Pharmaceutical Hot Melt Extruders Supported by 3D Smoothed Particle Hydrodynamics and 1D Predictive ModellingMatic JAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015Continuous Manufacturing of Immediate-Release Tablets from Hot-Melt Extruded Pellets Hörmann T; Laske S; Koscher G; Khinast J.GAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015A DEM model of Roller Compaction including Powder FeedingOrefice LAIChE Annual Meeting 2015; Salt Lake City; (USA)poster presentation
2015Solid-Liquid Separation for Pharmaceutical ProductionLaske S; Gursch J; Khinast J.GAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015Hot melt coating with lipid excipients for user-friendly solid dosage formsLopes D; Becker K; Haack D; Stehr M; Zimmer A; Salar-Behzadi SAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015Gluing Pills: A novel approach for processing of multi-layer tabletsSalar-Behzadi S; Stranzinger S; Lingitz J; Sacher S; Khinast JGAIChE Annual Meeting 2015; Salt Lake City; (USA)Oral presentation
2015A novel tool to standardize rheology testing of molten polymers for pharmaceutical applicationsTreffer D; Troiss A; Khinast J.GInternational Journal of Pharmaceuticspaper refereed
2015Identification of extractables and leachables of filter materials and their effect on human granulocyte colony-stimulating factor (hG-CSF)Wahl V; Mohr S; Münzer J; Khinast J; Paudel AE&L Europe 2015, London (UK)Oral presentation
2015Investigation of Segregation Effects in a Direct Compaction Process via Multipoint NIR Monitoring and NIR Chemical ImagingSacher S; Wahl P; Llusa M; Khinast J.GAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015NANEX: A Continuous Hot-Melt Extrusion (HME) Process for Nano-based FormulationsLaske S; Baumgartner R; Khinast J.G; Roblegg EAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015Development of a Control Strategy for Continuous Manufacturing of Solid Dosage FormsSacher S; Aigner I; Wahl P; Kleinebudde P; Rehbaum H; Khinast J.GAIChE Annual Meeting 2015; Salt Lake City; (USA)oral presentation
2015Amorphous solid dispersion of poorly soluble API by HME and spray drying: a rational screeing approachPaudel A; Mercuri A; Mohr S; Bresciani M; Khinast JAIChE Annual Meeting 2015; Salt Lake City; (USA)Oral presentation
2015Keynote - Hot Melt Extrusion for Continuous Pharma Production Khinast J.GPharma meets Polymer 2015; Würzburg (GE)oral presentation
2015Stability by design: Utilizing material science principles to predict physical an chemical stability of pharmaceutical solidsBrunsteiner M; Gressl C; Khinast JG; Paudel A; Davis L; Landis M; Pencheva K; Scrivens G; Wood GAIChE Annual Meeting 2015; Salt Lake City; (USA)Oral presentation
2015Accuracy of micro powder dosing and feeding via a vibratory sieve chutePaudel A; Besenhard M; Faulhammer E; Fathollahi S; Reif G; Calzolari V; Biserni S; Ferrari A; Lawrence S; Llusá M; Khinast JGAIChE Annual Meeting 2015; Salt Lake City; (USA)Oral presentation
2015Printed Medicine for personalized applications (talk)Pichler H; Planchette C; Wimmer-Teubenbacher M; Hsiao WK; Stegemann S; Khinast JPrinted Electronics USAOral presentation
2015Small Angle X-rayScattering in Modern Drug Development Self-Emulsifying Drug Delivery Systems (SEDDS)Planchette C Mercuri A Laggner PBruker application noteOther
2015Schmelzeextrusion in der pharmazeutischen IndustrieLaske S; Koscher G; Khinast J.G24. Leobener Kunststoffkolloquium (AT)oral presentation
2015Schmelzeextrusion in der pharmazeutischen IndustrieLaske S; Koscher G; Khinast J.G24. Leobener Kunststoffkolloquium 2015 (AT)proceedings
2015Accuracy of Micro Powder Dosing via a Vibratory Sieve-Chute System and FeedingFaulhammer E; Besenhard M; Calzolari V; Paudel A; Khinast J 15 AICHE annual meeting Saltlake CityOral presentation
2015Vacuum Compression Molding as Screening Approach for Hot-Melt Extruded Dosage FormsHörmann T.R., Treffer D., Koscher G., Khinast J.G.AIChE Annual Meeting 2015; Salt Lake City; (USA)poster presentation
2015Rigorous modeling of CO2 absorption and chemisorption: The influence of bubble coalescence and breakageGruber MC; Radl S; Khinast J.GChemical Engineering Sciencepaper refereed
2015Microdosing and Feeding of Inhalation Powders via a Vibratory Sieve-Chute SysteFaulhammer E; Besenhard M; Llusa M; Biserni S; Calzolari V; Ferrari A; Paudel A; Khinast JGDDL26, Edinburgh 2015 (UK)poster presentation
2015Advanced In Silico Modeling of the Performance of Inhalation ProductsSalar-Behzadi S; Wu S; Meindl C; Stranzinger S; Mercuri A; Mohr S; Bresciani M; Khinast JG; Fröhlich EDDL26, Edinburgh 2015 (UK)poster presentation
2015Characterization of the nanostructure crystallinity and specific surface of lactose based inhaler powders: Small- and Wide-Angle X-ray scattering (SWAXS) studiesWahl V; Zimmer A; Khinast JG; Paudel A; Laggner PDDL26, Edinburgh 2015 (UK)poster presentation
2015Analysis of Large-Scale Tablet Coating - Modeling; Simulation and ExperimentsBoehling P; Toschkoff G; Knop K; Kleinebudde P; Just S; Funke A; Rehbaum H; Khinast J.GJournal of Pharmaceutical Science Europe SI PATpaper refereed
2015Continuous Low-dose Feeding of Highly Active APIs in Hot-Melt ExtrusionLlusa M; Mohr S; Baumgartner R; Paudel A; Koscher G; Khinast JGDrug Development and Industrial Pharmacypaper refereed
2015Dynamic mechanical analysis of HPMC capsule shells bearing different bulk mechanical properties prepared by different processesFaulhammer E; Wahl V; Gregorova A; Markl D; Lawrence S; Khinast J; Paudel ADDL26, Edinburgh 2015 (UK)poster presentation
2015Modeling of an active tablet coating processToschkoff G; Just S; Knop K; Kleinebudde P; Funke A; Djuric D; Scharrer G; Khinast J.GJournal of Pharmaceutical Sciences paper refereed
2015Carrier-based Dry Powder Inhalation Part I: Impact of carrier modification on capsule filling processability and in vitro aerodynamic performanceZellnitz S; Faulhammer E; Wahl V; Khinast J; Paudel ADDL26, Edinburgh 2015 (UK)poster presentation
2015Development of a design space and predictive statistical model for capsule filling of low fill weight inhalation productsFaulhammer E; Llusa M; Wahl P; Paudel A; Lawrence S; Biserni S; Calzolari V; Khinast JDrug Delivery to the Lungs (DDL), UKposter presentation
2015Carrier-based Dry Powder Inhalation Part II: Impact of carrier material and API processing on the inter-particulate surface interactions in adhesive mixtures for inhalationZellnitz S; Faulhammer E; Wahl V; Schroettner H; Khinast J; Paudel ADDL26, Edinburgh 2015 (UK)poster presentation
2015Continuous low-dose feeding of highly active pharmaceutical ingredients in hot-melt extrusionLlusa M; Mohr S; Baumgartner R; Paudel A; Koscher G; Khinast JDrug Development and Industrial Pharmacypaper refereed
2015Continuous Drying of Small Particles for Pharmaceutical Applications—An Evaluation of Selected Lab-Scale SystemsGursch J; Hohl R; Armenante M; Dujmovic D; Van der Wel P; Brozio J; Krumme M; Rasenack N; Khinast J.GOrganic Process Research & Developmentpaper refereed
2015Understanding the impact of in vitro dissolution media and hydrodynamics on drug dissolution and releaseMercuri A Pagliari M Fares R Baxevanis F Fotaki NPBP 2016poster presentation
2015Indirect chiral separation of new recreational drugs by gas chromatography-mass spectrometry using trifluoroacetyl – L – prolyl chloride as chiral derivatization reagentWeiß J; Mohr S; Schmid MGChirality paper refereed
2015Polymeric formulations for drug release prepared by Hot Melt Extrusion; Application and characterizationStanković M; Frijlink HW; Hinrichs WLJDrug Discovery Todaypaper refereed
2015Solvent-free melting techniques for the preparation of lipid-based solid oral formulationsBecker K; Salar-Behzadi S; Zimmer A Pharmaceutical Researchpaper refereed
2015Influence of Papp values on prediction of plasma levels by in silico modeling of inhalation productsSalar-Behzadi S; Meindl C; Stranzinger S; Dzidic N; Mohr S; Wu S; Mercuri A; Zimmer A; Froelich EFirst European Conference on Pharmaceutics - Drug Deliveryposter presentation
2015Development of a Design Space and Predictive Statistical Model for Capsule Filling of Low-Fill-Weight Inhalation ProductsFaulhammer E; Llusa M; Wahl PR; Paudel A; Lawrence S; Biserni S; Calzolari V; Khinast JGDrug Development and Industrial Pharmacypaper refereed
2015Raman Spectroscopy in Pharmaceutical Product DesignPaudel A; Raijada D; Rantanen JAdvanced Drug Delivery Reviewspaper refereed
2015Die Trocknung partikelbeladener Pasten (paper)Brenn G; Steiner H; Planchette C; Kondor I; Mercuri ADECHEMApaper refereed
2015Structuring lipid coatings for modified drug releaseLopes D; Becker K; Zimmer A; Salar- Behzadi SDocday KFUposter presentation
2015Accuracy of Micro Powder Dosing via a Vibratory Sieve-Chute SystemBesenhard M; Faulhammer E; Fathollahi S; Reif G; Calzolari V; Biserni S; Ferrari A; Lawrence S; Llusa M; Khinast JGEuropean Journal of Pharmaceutics and Biopharmaceuticpaper refereed
2015Development of a design space and predictive statistical model for capsule filling of low fill weight inhalation productsFaulhammer E; Llusa M; Wahl P; Paudel A; Lawrence S; Biserni S; Calzolari V; Khinast JGDrug Development and Industrial Pharmacypaper refereed
2015Carrier-based Dry Powder Inhalation: Impact of Carrier Modification on Capsule Filling Processability and in vitro Aerodynamic PerformanceFaulhammer E; Wahl V; Zellnitz S; Khinast JG; Paudel AInternational Journal of Pharmaceuticspaper refereed
2015Printed Medicine for personalized applicationsPichler H Planchette C Wimmer-Teubenbacher M Paudel A Hsiao KW Stegemann S Khinast JPrinted Electronics Europeposter presentation
2015Retention-time Prediction for Polycyclic Aromatic Compounds in Reversed-phase Capillary Electro-chromatographFeenstra P; Gruber-Wölfler H; Brunsteiner M; Khinast JGJournal of Molecular Modelingpaper refereed
2015Design of experiments reveals critical parameters for pilot‐scale freeze‐and‐ thaw processing of L‐lactic dehydrogenaseRoessl U; Humi S; Leitgeb S; Nidetzky BBiotechnology Journalpaper refereed
2015Protein freeze concentration and micro-segregation analysed in a temperature-controlled freeze containerRoessl U; Leitgeb S; Nidetzky BBiotechnology Journalpaper refereed
2015Influence of surface characteristics of modified glass beads as model carriers in dry powder inhalers (DPIs) on the aerosolization performance.Zellnitz S; Schroettner H; Urbanetz NADrug Development and Industrial Pharmacypaper refereed
2015Crystallization speed of salbutamol as a function of relative humidity and temperatureZellnitz S; Narygina O; Resch C; Schroettner H; Urbanetz NAInternational Journal of Pharmaceuticspaper refereed
2015The influence of residual water on the secondary structure and crystallinity of freeze dried fibrinogenWahl V; Scheibelhofer O; Roessl U; Leitgeb S; deBeer T; Khinast JGInternational Journal of Pharmaceuticspaper refereed
2015The Use of SAXS for predicting Dissolution Rates of lyophilized FibrinogenWahl V Saurugger E Khinast J Laggner P1st European Conference on Pharmaceuticsposter presentation
2015Analysis of a new drug of abuse: Cathione derivative 1-(34-dimethoxyphenyl)-2-(ethylamino)pentan-1-oneWeiß JA; Taschwer M; Kunert O; Schmid MGJournal of Seperation Sciencepaper refereed
2015The influence of residual water on the solid state properties of freeze dried fibrinogenWahl V; Leitgeb S; Laggner P; Pichler H; Liebminger A; Khinast JGEuropean Journal of Pharmaceutics and Biopharmaceuticpaper refereed
2015The effect of the drying temperature on the properties of wet-extruded calcium stearate pellets: Pellet microstructure drug distribution solid state and drug dissolution.Schrank S; Kann B; Saurugger E; Hainschitz M; Windbergs M; Glasser B.J; Khinast J.G; Roblegg EInternational Journal of Pharmaceuticspaper refereed
2015Alcohol Dose Dumping: The Influence of Ethanol on Hot-Melt Extruded Pellets Comprising Solid LipidsJedinger N; Schrank S; Mohr S; Feichtinger A.; Khinast J.G.; Roblegg EEuropean Journal of Pharmaceuticspaper refereed
2015Kick-off talkKhinast J.GECCPM – Kick-off Meetingoral presentation
2015Continuous Manufacturing: Challenges and OpportunitiesKhinast J.GBohle Continuous Processing Inauguration Eventoral presentation
2015Pharmaceutical Nano-particle Production on Industrial Scale: Challenges and SolutionsKhinast J.GInternational Congress BioNanoMed; Graz (AT)oral presentation
2015Multi-scale Modeling in the Pharmaceutical IndustryKhinast J.GCAPE Forum; Paderborn (DE)oral presentation
2015Large-scale Multiphase Models for Pharmaceutical Manufacturing OptimizationKhinast J.GPSE-ESCAPE 2015; Copenhagen (DK)oral presentation
2015Continuous Pharmaceutical Manufacturing Advanced Manufacturing for Advanced ProductsKhinast J.GEUFEPS Annual Meeting 2015; Geneva (CH)oral presentation
2014Optical Coherence Tomography for In-line Quality Control of Pharmaceutical Film-Coated TabletsMarkl D; Hannesschläger G; Sacher S; Buchsbaum A; Leitner M; Khinast J.GIFPAC 2014; Arlington (USA)oral presentation
2014Nanotechnologie – vom Konzept zur AnwendungKhinast JGNano World Cancer Day 2014; Graz (AT)oral presentation
2014eSecMed Sichere Medikation für SeniorinnenSacher S; Bretitfuß G; Holweg GRFID Hotspot; Graz (AT)oral presentation
2014Application of QbD Principles for the Evaluation of Empty Hard Capsules
as an Input Parameter in Formulation Development and Manufacturing
Stegemann S; Connolly P; Matthews W; Barnett R; Aylott M; Schrooten K; Cadé D; Taylor A; Bresciani MAAPS PharmSciTechpaper refereed
2014Electron Microscopy of Pharmaceutical SystemsKlang V; Matsko NAdvances in Imaging and Electron Physicspaper refereed
2014Morphologies in solvent annealed clotrimazole thin films explained by Hansen-solubility parameterEhmann H; Zimmer A; Roblegg E; Werzer OCrystal Growth & Designpaper refereed
2014The Design of Controlled-Release Formulations Resistant to Alcohol-Induced Dose Dumping - A ReviewJedinger N; Khinast J.G; Roblegg EEuropean Journal of Pharmaceutics and Biopharmaceuticspaper refereed
2014Modeling a Seeded Continuous Crystallizer for the Production of Active Pharmaceutical IngredientsBesenhard M; Hodzic A; Eder R; Hohl R; Khinast J.GJournol of Crystal Research and Technologypaper refereed
2014The Role of Pharmaceutical Engineering in Modern Drug DevelopmentKhinast J.GAustrodrugs 2014; Vienna (AT)oral presentation
2014Fast real-time monitoring of entacapone crystallization and characterization of polymorphs via Raman spectroscopy; statistics and SWAXSJednačak T; Hodzic A; Scheibelhofer O; Marijan M; Khinast J.G; Novak PActa Pharmaceuticalpaper refereed
2014Fluid Bed Granulation: Towards a Comprehensive gSOLIDS ModelSchardmüller RC; Pieber M; Toschkoff G; Fraser S.D; Chilian B; Steigmiller D; Fetscher A; Maus M; Braun M; Khinast J.GAdvanced Process Modelling Forum; London (UK)poster presentation
2014PAT for Tableting: Inline Monitoring of API and Excipients via NIR SpectroscopyWahl P.R.; Fruhmann G; Sacher S; Straka G; Sowinski S; Khinast J.GEuropean Journal of Pharmaceutics and Biopharmaceuticspaper refereed
2014Personalisierte MedizinKhinast J.GPharmig Generalversammlung (AT)oral presentation
2014Tablet coating scale-up based on DEM simulations: going from lab- to industry-scaleToschkoff G; Dreu R; Knop K; Kleinebudde P; Altmeyer A; Funke A; Scharrer G; Khinast J.GAIChE 2014,
Atlanta (USA)
oral presentation
2014Fluid Bed Granulation: Towards a Comprehensive SOLIDS ModelSchardmüller R.C; Pieber M; Toschkoff G; Fraser S; Chilian B; Steigmiller D; Fetscher A; Maus M; Braun M; Khinast J.GAIChE 2014,
Atlanta (USA)
oral presentation
2014A novel method for modeling of complex wall geometries in smoothed particle hydrodynamicsEitzlmayr A; Koscher G; Khinast JComputer Physics Communicationpaper refereed
2014Improvement of adherence and safety of senior patients through multi-frequency RFID technology supported medicationStocker E; Heidenbauer S; Sacher S; Holweg G; Herndl T; Breitfuss G; Khinast J.GICPE 2014; Graz (AT)oral presentation
2014Feedback Control for a Continuous Crystallization ProcessBesenhard M.O; Ho C; Neugebauer P; Eder R.J; Khinast J.GInternational Congress on Pharmaceutical Engineering 2014 (ICPE); Graz (AT)poster presentation
2014Fluid Bed Granulation: Towards a Comprehensive gSOLIDS ModelSchardmüller R.C; Pieber M; Toschkoff G; Fraser S; Chilian B; Steigmiller D; Fetscher A; Maus M; Braun M; Khinast J.GInternational Congress on Pharmaceutical Engineering 2014 (ICPE); Graz (AT)poster presentation
2014Modeling Fluid Bed Granulation in a Comprehensive gSOLIDS ModelSchardmüller R.C; Pieber M; Toschkoff G; Fraser S.D; Chilian B; Steigmiller D; Fetscher A; Maus M; Bermingham S; Braun M; Khinast J.G10th Minisymposium Verfahrenstechnik; Vienna (AT)oral presentation
2014Investigating the uniformity of an active coating process by DEM simulations and experimental data Toschkoff G; Just S; Funke A; Djuric D; Knop K; Kleinebudde P; Scharrer G; Khinast J.GInternational Congress on Pharmaceutical Engineering 2014 (ICPE); Graz (AT)oral presentation
2014Total Surveillance! Inline Monitoring of Tablets via NIR Chemical ImagingWahl P; Scheibelhofer O; Sacher S; Kerschhaggl P; Khinast J.GICPE 2014; Graz (AT)oral presentation
2014Studying the details of tablet coating by using the Discrete Element MethodToschkoff G; Khinast JGAIChE Annual Meeting 2014,
Atlanta (USA)
oral presentation
2014A novel simulation approach for Hot Melt ExtrusionEitzlmayr A; Matic J; Koscher G; Khinast J.GICPE 2014; Graz (AT)oral presentation
2014A QbD approach to optimise electrochemical sensorsKondor I; Planchette C; Mercuri A; Scharrer G; Steiner H; Brenn GICPE 2014; Graz (AT)poster presentation
2014Die Face Pelletizing of Sticky HME FormulationsTreffer D; Koscher G; Khinast J.G ICPE 2014; Graz (AT)oral presentation
2014Effects of the Drying Temperature on the Final Properties of Calcium Stearate Micro-PelletsSchrank S; Kann B; Windbergs M; Glasser B.J; Zimmer A; Khinast J.G; Roblegg EICPE 2014; Graz (AT)poster presentation
2014Fully Coupled Multiphase Simulation of a Bottom-spray Wurster-Coater using a hybrid CPU/GPU CFD/DEM ApproachSiegmann E; Radeke C; Khinast J.GInternational Congress on Pharmaceutical Engineering 2014 (ICPE); Graz (AT)oral presentation
2014Probabilistic Modeling of Wet Collisions in Sheared Particle BedsMohan B; Khinast J.G; Radl SInternational Congress on Pharmaceutical Engineering 2014 (ICPE); Graz (AT)oral presentation
2014Simulation of a Fully two-way coupled Bottom Spray Wurster-coaterRadeke CInternational Congress on Pharmaceutical Engineering 2014 (ICPE); Graz (AT)oral presentation
2014Novel Developments for the Simulation of Hot Melt ExtrusionEitzlmayr A; Matic J; Koscher G; Khinast J.GLeistritz Pharma Workshop; Nuernberg (DE)oral presentation
2014The effects of powder compressibility, speed of capsule filling and pre-compression on plug densificationLlusa M; Faulhammer E; Biserni S; Calzolari V; Lawrence S; Bresciani M; Khinast JInternational Journal of Pharmaceuticspaper refereed
2014Label-free in-vitro visualization of particle uptake into the oral buccal epithelium by confocal Raman microscopyKann B; Teubl B; Roblegg E; Windbergs MAnalystpaper refereed
2014Comparing Manufacturing Process Options - A techno-economic profiling method supports process developmentFraser S; Dujmovic D; Khinast JPharmaceutical Technology Europepaper refereed
2014A Novel Simulation Approach for Hot Melt Extrusion
Khinast J.G2nd international symposium on Multiscale Multiphase Process Engineering (MMPE); Hamburg (DE)oral presentation
2014Introduction to tools for process characterisation/Design of ExperimentsKhinast J.GDIA QbD Workshoporal presentation
2014Mechanistic Modeling of Modular Co-Rotating Twin-Screw Extruders Eitzlmayr A; Koscher G; Reynolds G; Huang Z; Booth J; Shering P; Khinast J.GInternational Journal of Pharmaceuticspaper refereed
2014From Multiphase DNS to Large-scale Bioractor ModelsKhinast J.G7th International Berlin Workshop (IBW 7) on Transport Phenomena with Moving Boundaries and More; Berlin (DE)oral presentation
2014Computational investigation of scale effects in spouted fluidized bedsPrieling D, Khinast JG, Glasser BJAIChE 2014,
Atlanta (USA)
oral presentation
2014Always the Same? Location of Segregation via SpectroscopyScheibelhofer O; Hohl R; Wahl P; Sacher S; Khinast J.GAIChE 2014 Annual Meeting; Atlanta (USA)oral presentation
2014Residence Time Distribution Measurement via Video Analysis for Design of Experiment Characterization of Melt ExtrusionWahl P; Hörl G; Kaiser D; Sacher S; Khinast J.GAIChE 2014 Annual Meeting; Atlanta (USA)oral presentation
2014Fully Coupled Multiphase Simulation of a Bottom-spray Wurster-Coater using a hybrid CPU/GPU CFD/DEM ApproachSiegmann E; Radeke C; Khinast JGSINTEF CFD Conference 2014, Trondheimoral presentation
2014Condensation Reaction between Carbohydrazide and Salicylaldehyde: in-line Vibrational Spectroscopy Monitoring and Characterization of the Reaction Products in Solution and Solid State Jednačak T; Novak P; Hodzic A; Scheibelhofer O; Khinast J.G; Plavec J; Sket P; Parlov VActa chimica Slovenicapaper refereed
2014Calibration-free In-Line Monitoring of Pellet Coating Processes via Optical Coherence TomographyMarkl D; Zettl M; Hannesschläger G; Sacher S; Leitner M; Buchsbaum A; Khinast J.G Chemical Engineering Sciencepaper refereed
2014Optical Coherence Tomography as a Novel Tool for In-Line Monitoring of a Pharmaceutical Film-Coating ProcessMarkl D; Hannesschläger G; Sacher S; Leitner M; Khinast J.GEuropean Journal of Pharmaceutical Sciencespaper refereed
2014Use of mechanistic simulations as a quantitative risk-ranking tool within the quality by design frameworkStocker E; Toschkoff G; Sacher S; Khinast J.GInternational Journal of Pharmaceuticspaper refereed
2014Impact of Drying on Solid State Modifications and Drug Distribution in Ibuprofen-Loaded Calcium Stearate Pellets; Schrank S; Kann B; Saurugger E; Ehmann H; Werzer O; Windbergs M; Gasser B.J; Zimmer A; Khinast J.G; Roblegg EMolecular Pharmaceuticspaper refereed
2014Investigation of in silico models for lung deposition of an inhaled model drugFröhlich E; Mercuri A; Salar-Behzadi S; Wu S10th PBP World Meeting; Lisbon; (PT)poster presentation
2014In-line Quality Control of Moving Objects by Means of Spectral-Domain OCTMarkl D; Hannesschläger G; Buchsbaum A; Sacher S; Khinast J.G; Leitner MOptics and Lasers in Engineeringpaper refereed
2014An Integrated Downstream Process Development Strategy along QbD PrinciplesMeitz A; Sagmeister P; Langemann T; Herwig CMDPI AG
Bioengineering Open Access Journal
paper refereed
2014A techno-economic profiling methodology for a comparative evaluation of manufacturing process options Fraser .SD; Dujmovic D; Khinast J.GPharmaceutical Technology Europepaper refereed
2014Near-Infrared Light Spectroscopy: Applicability and New DevelopmentsScheibelhofer O; Sacher S; Khinast J.Guropean Pharmaceutical Review paper refereed
2014Alcohol Dose Dumping: Prerequisites for Successfully Developing a Robust Matrix-Based System via Hot-Melt ExtrusionJedinger N; Khinast J.G; Roblegg E; Mohr S; Feichtinger AEuropean Journal of Pharmaceutics and Biopharmaceuticspaper refereed
2014The Simulation of Mixing and Free Surface Flows in Co-Rotating Twin-Screw ExtrudersEitzlmayr A; Kondor I; Matic J; Koscher G; Khinast J.GAIChE 2014 Annual Meeting; Atlanta (USA)oral presentation
2014Reviving QbD using mechanistic toolsSagmeister P; Herwig C3rd BioProScale Conference, Berlin (DE)oral presentation
2014Concepts for integrated Bioprocess DesignLangemann TLife Science Meeting; Krems; 2014 (AT)oral presentation
2014A novel approach for producing recombinant human protein in E.coli using the Bacterial Ghost platform technologyLangemann T; Wurm DJBiomaterials, Radebeul, 2014poster presentation
2014An integrated downstream process development strategy along QbD principlesMeitz AICPE 2014; Graz (AT)poster presentation
2014Investigating the influence of temperature on the bonding mechanisms during roller compaction of ibuprofen sodiumLopes D8th Pharmaceutical Solid State Research Cluster (PSSRC); Porotroz (SVK)oral presentation
2014Optimization of a industrial scale capsule filling process - PSSRCFaulhammer E8th PSSRC Annual Symposium; Ljubljana (SI)oral presentation
2014Impact of carrier decantation and dosator capsule filling process on DPI performance Wahl VEuropean Journal of Pharmaceutics and Biopharmaceuticspaper refereed
2014Specific surface, crystallinity and dissolution of lyophilized fibrinogen. A study by combined small and x-ray scattering (SWAXS)Wahl V; Saurugger E; Khinast J.G; Laggner PEuropean Journal of Pharmaceutics and Biopharmaceuticpaper refereed
2014Changes in secondary structure and crystallinity of human fibrinogen due to residual waterWahl V8th PSSRC Annual Symposium; Ljubljana (SI)oral presentation
2014Real-time data processing for in-line monitoring of a pharmaceutical coating process by optical coherence tomographyMarkl D; Ziegler J; Hannesschläger G; Sacher S; Buchsbaum A; Leitner M; Khinast J.GBiophotonics: Photonic Solutions for Better Health Care IVproceedings
2014Optical coherence tomography data processing for in-line monitoring of a pharmaceutical film-coating processMarkl D; Hannesschläger G; Sacher S; Buchsbaum A; Khinast J.GProceedings of the 10th Minisymposium Verfahrenstechnikproceedings
2014100% Monitoring of Manufactured Tablets with NIR Chemical ImagingWahl P; Scheibelhofer O; Sacher S; Kerschhaggl P; Khinast J.GEuroPACT 2014; Barcelona (ES)poster presentation
2014Die Face Pelletizing of Sticky HME FormulationsTreffer D; Koscher G; Khinast J.G AICHE 2014 annual meeting; Atlanta (USA)oral presentation
2014Continuous API-crystal coating via coacervation in a tubular reactorBesenhard M.O; Thurnberger A; Hohl R; Faulhammer E; Rattenberger J; Khinast J.GInternational Journal of Pharmaceuticspaper refereed
2014Transformation of a Phenytoin Nanosuspension into a Solid Oral Dosage Form via Nano-Extrusion (NANEX )Baumgartner  R Eitzlmayr A Matsko N Tetyczka C. Khinast J Roblegg ESchladming Österreich;47. Wissenschaftliche Fortbildungswoche der Österreichischen Apothekerkammerposter presentation
2014Tailoring drug delivery to the lung by using modified glass beads as model carrierZellnitz S Schroettner H Kappl M Urbanetz NAControlled release society (CRS) local chapter meeting – site specific and controlled delivery.poster presentation
2014Untersuchung des Einflusses von Alkohol auf lipophile schmelzextrudierte PelletsJedinger N Khinast J Roblegg E47. Wissenschaftliche Fortbildungswoche der Österreichischen Apothekerkammer 23.-28. Februar 2014 Schladmingposter presentation
2014Characterization of a laboratory-scale container for freezing protein solutions with detailed avaluation of a freezing process simulationRoessl U; Jajcevic D; Leitgeb S; Khinast JG; Nidetzky BJournal of Pharmaceutical Sciencespaper refereed
2014The influence of water on the solid state properties of freeze dried proteinsWahl V Leitgeb S Khinast J 9th worldmeeting on Pharmaceutics Biopharmaceutics and Pharmaceutical Technologyposter presentation
2014 Nano-extrusion: A Promising Strategy for the Oral Drug Delivery MarketBaumgartner  R Khinast J Roblegg E23rd Scientific Congress of the Austrian Pharmaceutical Society (ÖPHG) -> EuroNanoTox Posterpreisposter presentation
2014Manufacturing of a Solid Phenytoin Nanoparticle Formulation via NanoextrusionBaumgartner  R Khinast J Roblegg E9th World Meeting on Pharmaceutics Biopharmaceutics and Pharmaceutical Technologyposter presentation
2014Design of pharmaceutical products to meet future patient needs requires modification of current development paradigms and business modelsStegemann S; Baeyens JP; Becker R; Maio M; Bresciani M; Shreeves T; Azadi C; Ecker F; Gogol MZeitschrift für Gerontologie und Geriatriepaper refereed
2014Investigation of surface modified glass beads as potential carriers in dry powder inhalersZellnitz S Schroettner H Kappl M Urbanetz NA23rd Scientific Congress of the Austrian Pharmaceutical Societyposter presentation
2014How Does Alcohol Impact Hot-Melt Extruded Pellets Comprising Solid Lipids as Functional Additives?Jedinger N Khinast J Roblegg E23rd Scientific Congress of the Austrian Pharmaceutical Society (ÖPhG) 23-25 April 2014 Grazposter presentation
2014The influence of ethanol on Hot-Melt Extruded Pellets Containing Solid Lipids as Functional ExcipientsJedinger N Khinast J Roblegg E9th World Meeting on Pharmaceutics Biopharmaceutics and Pharmaceutical Technology 31 March to 3 April 2014 Lisbonposter presentation
2014NANEX: A Rational Design of the Manufacturing of a Solid Oral Nanoparticle FormulationBaumgartner  R Khinast J Roblegg E6th International Congress on Pharmaceutical Engineering (ICPE)oral presentation
2014Nano-Extrusion (NANEX): A Promising Tool for the Oral Drug Delivery MarketBaumgartner  R Khinast J Roblegg ENuernberg Germany; Pharmaworkshop Leistritzoral presentation
2014The influence of residual water on the reconstitution behavior of lyophilized human fibrinogenWahl V Leitgeb S Laggner P Khinast JInternational Congress on Pharmaceutical Engineering 2014 (ICPE) Graz (AT)poster presentation
2014Bacterial Ghost Platform Technology for Pharmaceutical Protein Production Langmann T Meitz A Sagmeister P Herwig CInternational Congress on Pharmaceutical Engineering 2014 (ICPE) Graz (AT)poster presentation
2014Novel Strategy for Downstream Process Development along QbD PrinciplesMeitz A Sagmeister P Langemann Herwig CInternational Congress on Pharmaceutical Engineering 2014 (ICPE) Graz (AT)poster presentation
2014Freezing of Pharmaceutical Proteins: Benefits of Process Characterization at Reduced Scales Pittermann B Roessl UInternational Congress on Pharmaceutical Engineering 2014 (ICPE) Graz (AT)oral presentation
2014Surface coverage of surface modified glass beads as model carriers in dry powder inhalers influences the FPFZellnitz S Schroettner H Urbanetz NA6th International Congress on Pharmaceutical Engineering (ICPE)poster presentation
2014Development of a Drug Abuse-Alcohol-Resistant Formulation Produced via Hot-Melt ExtrusionJedinger N Khinast J Roblegg E6th International Congress on Pharmaceutical Engineering (ICPE) June 16th-17th  2014 Grazposter presentation
2014Development of Lipophilic Hot-Melt Extruded Alcohol-Resistant Pellets Containing NicomorphineJedinger N Khinast J Roblegg E Mohr S Feichtinger A6th International Congress on Pharmaceutical Engineering (ICPE) June 16th-17th  2014 Grazposter presentation
2014Tailored protein release from biodegradable multiblock-copolymer implants prepared by hot melt extrusionStankovic MICPE 16-17 June 2014 Grazoral presentation
2014DPI performance of tailor-made spray dried mannitol and salbutamol sulphate particles Mönckedieck M Kamplade J Fakner P Steckel H Walzel PInternational Congress on Pharmaceutical Engineering 2014 (ICPE) Graz (AT)oral presentation
2014Miscibility processing and stability considerations of spray-dried amorphous solid dispersion: A tale of naproxen-PVP systemPaudel A; Loyson Y; Van Den Mooter GInternational Congress on Pharmaceutical Engineering 2014 (ICPE) Graz (AT)oral presentation
2014The Stability of Amorphous Solid Dispersions - What can We Learn from Mathematical Models?Brunsteiner M Paudel A Khinast J International Congress on Pharmaceutical Engineering 2014 (ICPE) Graz (AT)oral presentation
2014In-situ protein secondary structure determination in ice: Raman spectroscopy-based process analytical tool for frozen storage of biopharmaceuticalsRoessl U; Leitgeb S; Pieters S; De Beer T; Nidetzky BJournal of Pharmaceutical Sciencespaper refereed
2014Chiral separation of cathinone and amphetamine derivatives by HPLC/UV using sulfated ß-cyclodextrin as chiral mobile phase additiveTaschwer M; Seidl Y; Mohr S; Schmid MGChiralitypaper refereed
2014Lipid structuring for controlled drug release: polymorphic crystallization and curing effectsLopes D; Becker K; Haack D; Lochmann D; Zimmer A; Salar-Behzadi S8th PSSRC 2014 Ljubljana (SL) oral presentation
2014The influence of residual water on the secondary structure and crystallinity of freeze dried fibrinogenWahl V Scheibelhofer O Roessl U Leitgeb S deBeer T Khinast J8th PSSRC Annual Meeting. Ljubljanaoral presentation
2014Structural and Dynamic Properties of Amorphous Solid Dispersions: The Role of Solid-State Nuclear Magnetic Resonance Spectroscopy and RelaxometryPaudel A; Geppi M; Van den Mooter GJournal of Pharmaceutical Sciencespaper refereed
2014Advanced structuring of lipids for controlled drug release: polymorphic crystallizations and curing effects.Lopes D; Becker K; Faulhammer E; Haack D; Lochmann D; Khinast J; Zimmer A; Salar-Behzadi S14 AICHE annual meeting Atlanta GA (USA)oral presentation
2014Compariing physically and chemically modified glass beads as model carrier particles in dry powder inhalersZellnitz S. Schroettner H. Kappl M. Urbanetz N.A.American Institute of Chemical Engineers (AIChE) Annual Meeting 2014. Atlantaoral presentation
2014Tailoring drug detachment by surface modification of glas beads as modelcarrier in dry powder inhalersZellnitz S Kappl M Urbanetz NAAPV Lissabon 2014poster presentation
2014Investigating the influence of carrier morphology and dosator capsile filling process on the performance of dry powder inhalers(DPIs)Zellnitz S; Faulhammer E; Wahl V; Schroettner H; Khinast J14 AICHE annual meeting Atlanta GA (USA) on 18th November 2014 oral presentation
2014Brazilin blocks catabolic processes in human chondrocytes via inhibition of NFKB1/p50".Bieder D; Wu S; Walzer S; Unger F; Reznicek G; Holzer W; Hobusch G; Windhager R; Goldring M; Viernstein H; Toegel SPlos onepaper refereed
2014Specific surface crystallinity and dissolution of lyophilized fibrinogen. A study by combined small- and wide-angle X-ray scattering (SWAXS)Wahl V; Saurugger E; Khinast JG; Laggner PEuropean Journal of Pharmaceutics and Biopharmaceuticspaper refereed
2014The effects of material attributes on capsule fill weight and weight variability in dosator nozzle machines. Faulhammer E; Llusa M; Radeke C; Scheibelhofer O; Lawrence S; Biserni S; Calzolari V; Khinast JGInternational Journal of Pharmaceuticspaper refereed
2014Towards the optimisation and adaptation of dry powder inhalersCui Y; Schmalfuß S; Zellnitz S; Sommerfeld M; Urbanetz NAInternational Journal of Pharmaceuticspaper refereed
2014Nano-extrusion: A promising tool for continuous manufacturing of solid nano-formulationsBaumgartner R; Eitzlmayr A; Matsko N; Tetyczka C; Khinast JG; Roblegg EInternational Journal of Pharmaceuticspaper refereed
2014Creating a design space for low dose capsule filling of products for inhalationFaulhammer E; Llusa M; Biserni S; Calzolari V; Lawrence SM; Khinast JAPV: 9th Worldmeeting on Pharmaceutics and Biopharmaceuticsposter presentation
2014Hot-melt coating - taste-masked multiparticulate drug delivery systems with immediate drug releaseSalar-Bahzadi S8th PSSRC Annual Symposium Ljubljanaoral presentation
2014Microdosing of pharmaceutical products into capsulesFaulhammer E; Besenhard M; Fathollahi S; Reif G; Calzolari V; Biserni S; Ferrari A; Lawrence S; Llusa M; Khinast J14 AICHE annual meeting Atlanta GA (USA) on 18th November 2014 oral presentation
2014Structural Characterization of Amorphous Solid Dispersionsvan den Mooter G Meeus J Paudel A Book: Amorphous Solid Dispersions in AAPS series: Advances in Delivery Science and Technology 2014 pp 421-485book contribution
2014Particular film formation of phenytoin at silica surfacesWerzer O; Baumgartner R; Zawodzki M; Roblegg EMolecular Pharamaceuticspaper refereed
2014One polymorph - various morphologies of phenytoin at a silica surface due to preparation kineticsEhmann H Baumgartner R Reischl D Roblegg E Zimmer A Resel R Werzer OCrystal Growth & Designpaper refereed
2014Crystallographic Textures and Morphologies of Solution Cast Ibuprofen Composite Films at Solid SurfacesKellner T; Ehmann HMA; Schrank S; Kunert B; Zimmer A; Roblegg E; Werzer OMolecular Pharmaceuticspaper refereed
2014Comparison of two in silico models to assess lung deposition of inhaled salbutamolMercuri A; Salar-Behzadi S; Wu S; Froehlich EPBP World Meetingposter presentation
2014Scale up of a low-dose capsule filling process for inhalation produtcsFaulhammer E; Llusa M; Biserni S; Calzolari V; Lawrence SM; Khinast JPSSRC Meeting Ljubljanaoral presentation
2014Dissolution Testing of Hardly Soluble Materials by surface sensitive techniques: Clotrimazole from an Insoluble MatrixEhmann HMA; Winter S; Griesser T; Keimel R; Schrank S; Zimmer A; Werzer OPharmaceutical Researchpaper refereed
2014Morphologies of Phenytoin Crystals at Silica Model Surfaces: Vapor Annealing versus Drop CastingEhmann HMA; Baumgartner R; Kunert B; Zimmer A; Roblegg E; Werzer OThe journal of physical chemistrypaper refereed
2014A proposal for a drug product Manufacturing Classification System (MCS) for oral solid dosage formsLeane M Pitt K Reynolds G et al.Pharmaceutical Development and Technologybook contribution
2014Effect of Compression on Local and Segmental Mobility of Poly (1-vinylpyrrolidone-co-vinyl acetate): Broadband Dielectric Spectroscopy StudyWorku ZA; Vanroy B; Wübbenhorst M; Paudel A; Van den Mooter G8th PSSRC 2014 Ljubljana (SL) paper refereed
2014Die Trocknung partikelbeladener PastenBrenn G Steiner H Planchette C Kondor I Mercuri A Scharrer GDECHEMAposter presentation
2014Lipids for API microencapsulation: Effect of processing conditions on product performanceLopes D; Becker K; Zimmer A; Salar- Behzadi SDocday KFUOral presentation
2014Low-dose capsule filling of inhalation products: critical material attributes and process parametersFaulhammer E; Fink M; Llusa M; Lawrence S; Biserni S; Calzolari V; Khinast JGInternational Journal of Pharmaceuticspaper refereed
2014Advanced structuring of lipids for controlled drug release; Polymorphic crystallizations and curing effectsLopes D; Becker K; Faulhammer E; Haack D; Lochmann D; Khinast J; Zimmer A; Behzadi SAIChE 2014Oral presentation
2014Investigation of Migrant–Polymer Interaction in Pharmaceutical Packaging Material Using the Linear Interaction Energy AlgorithmFeenstra P; Brunsteiner M; Khinast JGJournal of Pharmaceutical Sciencespaper refereed
2014Tailored protein release from multiblock copolymer implants made by hot melt extrusion (ICPE)ICPE 2014; Graz (AT)Oral presentation
2014In situ protein secondary structure determination in ice: Raman spectroscopy-based process analytical tool for frozen storage of biopharmaceuticalsRoessl U; Leitgeb S; Pieters S; deBeer T; Nidetzky BJournal of Pharmaceutical Sciencespaper refereed
2014Freezing of Pharmaceutical Proteins: Benefits of Process Characterization at Reduced ScalesICPE 2014; Graz (AT)Oral presentation
2014Surface modified glass beads as model carriers in dry powder inhalers—Influence of drug load on the fine particle fraction.Zellnitz S; Schroettner H; Urbanetz NAPowder Technologypaper refereed
2014Effect of lyoprotectants on β-glucosidase activity and viability of Bifidobacterium infantis after freeze-drying and storage in milk and low pH juicesBasholli-Salihu M; Mueller M; Salar-Behzadi S; Unger F; Viernstein HLWT - Food Science and Technologypaper refereed
2014Toxicological Assessment of Inhaled Nanoparticles: Role of in Vivo ex Vivo in Vitro and in Silico Studies ReviewFröhlich E; Salar-Behzadi SInternational Journal of Molecular Sciencepaper refereed
2014Oral pharmaceutical composition comprising taste-masked N-AcetylcysteineBecker K; Zimmer A; Salar-Behzadi SDocday KFUoral presentation
2014Chiral separation of new cathinone and amphetamine related designer drugs using a Chiralpak AS-H column in normal phase HPLCMohr S Taschwer M Schmid MG23rd Scientific Conference of the Austrian Pharmaceutical Societyposter presentation
2014Hot melt coating - taste masked oral multiparticulate drug delivery systems with immediate drug releaseBecker K; Salar-Behzadi S; Zimmer A PSSRCoral presentation
2014Inducing triglycerides stable polymorph crystallization by hot melt coatingLopes D; Becker K; Haack D; Lochmann D; Kordik T; Salar-Behzadi S; Zimmer APBP World Meetingposter presentation
2014Evaluation of the surface free engergy of inhalable powdersZellnitz S; Redlinger Pohn JD; Schroettner H; Kappl M; Urbanetz NADDL26poster presentation
2014Coating of glass substrates to prevent alkali ion diffusion into pharmaceutical solutionsSchweiger S; Neubauer C; Fraser S; Klein T; Schennach R; Reichmann A; Gruber-Wölfler HSurface and Coating Technologypaper refereed
2014TiO2-Nanocoatings on Glass Surfaces to Reduce Alkali Ion Diffusion into Pharmaceutical SolutionsGruber-Wölfler H; Schweiger S; Fraser S; Reichmann AChemie Ingenieur Technikother
2014In-line implementation of an image-based particle size measurement tool to monitor hot-melt extruded pelletsTreffer D; Wahl P; Hörmann T; Markl D; Schrank S; Jones I; Cruise P; Mürb R; Koscher G; Roblegg E; Khinast J.G International Journal of Pharmaceuticspaper refereed
2014Impact of Drying on Solid State Modifications and Drug Distribution in Ibuprofen-Loaded Calcium Stearate PelletsSchrank S; Kann B; Saurugger E; Ehmann H; Werzer O; Windbergs M; Glasser B.J; Zimmer A; Khinast J.G; Roblegg EMolecular Pharmaceuticspaper refereed
2013Experimental Analysis of Tablet Properties for Modeling of an Active Coating ProcessJust S; Toschkoff G; Funke A; Djuric D; Scharrer G; Khinast J.G; Knop K; Kleinebudde PAAPS PharmSciTechpaper refereed
2013Developing and advancing dry powder inhalation towards enhanced therapeuticsStegemann S; Kopp B; Borchard G; Shah V.P; Senel S; Dubey F; Urbanetz N.A; Cittero M; Schoubben A; Hippchen C; Cadé D; Fuglsangm A; Morais J; Borgström L; Farshi F; Seyfang K.H; Hermann R; Van de Putte A; Klebovich I; Hincal AEuropean Journal of Pharmaceutical Sciencespaper refereed
2013Application of QbD in formulation development using a high-throughput method;experimental design and statistical data evaluationLeitgeb SPepTalk 2013; Palm Springs (USA)oral presentation
2013QbD compliant development of a freeze/thaw process – from formulation development to large-scale freezingRoessl U; Jajcevic D; Leitgeb S; Nidetzky BPepTalk 2013; Palm Springs (USA)poster presentation
2013Hydrophobic patches Promote Attraction - Why and How; and Do They Really?Brunsteiner MPepTalk 2013; Palm Springs (USA)oral presentation
2013Surface induced order of solution processed caffeine needles on silica and muscovite micaWerzer O; Kunert B; Roblegg E; Zimmer A; Oehzelt M; Resel R Crystal Growth & Designpaper refereed
2013Differential scanning fluorescence approach using a fluorescent molecular rotor to detect thermostability of proteins in surfactant-containing formulationsAblinger E; Leitgeb S; Zimmer AInternational Journal of Pharmaceuticspaper refereed
2013Thinking continuously: a microreactor for the production and scale-up of biodegradable; self-assembled nanoparticlesPetschacher C; Eitzlmayr A; Besenhard M; Wagner J; Barthelmes J; Bernkop-Schnürch A; Khinast J.G; Zimmer APolymer Chemistrypaper refereed
2013Shaking and stirring: Comparison of controlled laboratory stress conditions applied to the human growth hormoneWiesbauer J; Cardinale M; Nidetzky BProcess Biochemistrypaper refereed
2013Pharmazeutisches Engineering – Ein Schlüssel für die Zukunft der PharmaindustrieKhinast JGGastvortrag am Lehrstuhl für Mechanische Verfahrenstechnik der Fakultät Bio- und Chemieingenieurwesen an der Technischen Universität Dortmund (DE)other
2013In vitro permeability studies of neutral polystyrene particles through the buccal mucosa
Teubl B; Meindl C; Eitzlmayr A; Zimmer A; Fröhlich E; Roblegg ESmallpaper refereed
2013Der dynamische Böschungswinkel zur Bestimmung von Reibungskoeffizienten für DEM Simulationen von ÜberzugsprozessenJust S; Toschkoff G; Funke A; Djuric D; Scharrer G; Khinast J.G; Knop K; Kleinebudde PJahrestreffen der Fachgruppen Agglomerations- und Schüttguttechnik; Weimar (DE)other
2013A CFD-DEM Coupling Method for Large-Scale Simulations of Fluidized SystemsKhinast JGJahrestreffen der Fachgruppen Agglomerations- und Schüttguttechnik und Computational Fluid Dynamics, Weimar (DE)oral presentation
2013Monitoring Blending of Pharmaceutical Powders with Multi-point NIR SpectroscopyScheibelhofer O; Balak N; Wahl P; Koller D; Glasser B.J; Khinast J.GAAPS PharmSciTechpaper refereed
2013Optimization of Inter-Tablet Coating Uniformity in an Active Coating ProcessJust S; Toschkoff G;Funke A; Djuric D; Khinast J.G; Knop K; Kleinebudde PPolish-German Symposium on Pharmaceutical Sciences; Danzig (PL)poster presentation
2013Optimization of Inter-Tablet Coating Uniformity in an Active Coating ProcessJust S; Toschkoff G; Funke A; Djuric D; Scharrer G; Khinast J.G; Knop K; Kleinebudde P6th International Symposium on Solid Oral Dosage Forms; Malmö (SE)poster presentation
2013DoE investigation of tablet coating simulations using the Discrete Element Method: uniformity improvementToschkoff G; Just S; Scharrer G; Knop K; Kleinebudde P; Djuric D; Altmeyer A; Funke A; Khinast J.GPARTEC 2013; Nuremberg (DE)poster presentation
2013Coalescence of armored interface under impactPlanchette C; Biance A.L; Pitois O; Lorenceau E Physics of Fluidspaper refereed
2013The Influence of Ethanol on Hot Melt Extruded Micropellets Containing Compritol® and Precirol® as AdditivesJedinger N; Koscher G; Khinast J.G; Roblegg E9. Minisymposium der Verfahrenstechnik; Leoben (AT)poster presentation
2013The Effect of Capsule-Filling Machine Vibrations on Average Fill Weight of CapsulesFaulhammer E; Llusa M; Lawrence S; Biserni S; Calzolari V; Khinast J.G9. Minisymposium der Verfahrenstechnik; Leoben (AT)poster presentation
2013Einfluss des Restwassergehaltes auf das Aggregationsverhalten lyophilisierter ProteinbatchesWahl V; Piller M; Leitgeb S; Khinast J.G9. Minisymposium der Verfahrenstechnik; Leoben (AT)poster presentation
2013Characterization of physically modified glass beads as potential carrier particles in dry powder inhalatesZellnitz S; Redlinger-Pohn J.D; Schroettner H; Kappl M; Urbanetz N.A9. Minisymposium der Verfahrenstechnik. Leoben (AT)poster presentation
2013Freezing process development under QbD principles – In silico solutions for process characterization and scalingRoessl U; Jajcevic D; Leitgeb S; Nidetzky BBioprocess International Europe 2013; Düsseldorf (DE)poster presentation
2013Bringing ICH Q10 to life – Knowledge management for efficient life-cycle management in the context of QbDLeitgeb S; Trattner CBioprocess International Europe 2013; Düsseldorf (DE)oral presentation
2013Continous Crystallization of Pharmaceuticals in a Tubular Reactor: Application & LimitationsBesenhard M; Llusa M; Gursch J; Khinast J.GECCE9 / ECAB2; The Hague (NL)oral presentation
2013Characterization of Screen Printable Pastes and Resulting Thick Films: Application to Electrochemical SensorsPlanchette C; Brenn GECCE9 / ECAB2; The Hague (NL)oral presentation
2013Designing and Developing Drug Products for Older Adults: the role of patient centric drug delivery to achieve therapeutic goals
The changing patient population and the growing challenge of adherence
Bresciani MGlobal Formulation and Drug Delivery; Amsterdam (NL)oral presentation
2013Impacts of liquid marblesPlanchette CGroup of Bernhard Weigand; Institute of Aerospace Thermodynamics; TU Stuttgart; (GE)oral presentation
2013Impacts of liquid marblesPlanchette CGroup of Dieter Bothe; Center of Smart Interfaces; TU Darmstadt; (DE)oral presentation
2013Surface modified model carrier particles for the use in dry powder inhalatesZellnitz S; Redlinger-Pohn J.D; Schroettner H; Kappl M; Urbanetz N.AInternational Congress on Particle Technology (PARTEC). Nürnberg (DE)poster presentation
2013Correlation of conductive flux and Contact stress - Lessons learned from Simple shearMohan B; Radl S; Khinast J.GMinisymposium for Process Engineering; Leoben (AT)poster presentation
2013Modelling of Granular Systems in the Context of Pharmaceutical ManufacturingKhinast JGPartec – International Congress on Particle Technology 2013; Nürnberg (DE)oral presentation
2013Fully Coupled Multiphase Simulation of a Bottom-spray Wurster-Coater using a hybrid CPU/GPU CFD/DEM ApproachRadeke C; Jajcevic D; Siegmann E; Khinast J.GPARTEC 2013; Nuremberg (DE)oral presentation
2013Numerical Simulation of the Water Evaporation from an Aqueous Mannitol Solution on a Single Droplet ScaleGopireddy S.R; Koester M; Urbanetz N.A; Gutheil EPARTEC 2013; Nuremberg (DE)poster presentation
2013Preparation and characterization of physically modified glass beads used as model carriers in dry powder inhalersZellnitz S; Redlinger-Pohn J.D; Kappl M; Schroettner H; Urbanetz N.AInternational Journal of Pharmaceuticspaper refereed
2013Colloidal Interactions and Protein Aggregation --- Insights from a Simple In-silico ModelBrunsteiner M; Flock M; Nidetzky BPlos Onepaper refereed
2013Investigation of the physiological response to oxygen limited process conditions of Pichia Pastoris Mut+ strain using a two-compartment scale-down systemLorantfy B; Jazini M; Herwig CJournal of Bioscience and Bioengineeringpaper refereed
2013QbD principles - next generation of manufacturing processes and personalized medicineBresciani MBio Connect 2013; Poznan (PL)oral presentation
2013A model for the conductive heat flux in granular flows based on a correlation with contact pressureMohan B; Radl S; Khinast J.GFluidization XIV From Fundamentals to Products; Noordwijkerhout (NL)poster presentation
2013Optimierung der Qualitätsmerkmale von Pulverinhalaten mit beliebigem inhalativen Wirkstoff durch Einsatz sprühgetrockneter Mannitolträgerpartikel mit maßgeschneiderter OberflächenrauheitKöster M; Urbanetz N.AJahrestreffen DFG 2013 Berlin (DE)oral presentation
2013Das Drucken patientenspezifischer pharmazeutischer Formulierungen als technischer Ansatz für zukünftige Anwendungen in der personalisierten MedizinFraser S.D; Gruber M.M; Bauer W; Brenn G; Zimmer A; Khinast J.GTechnoPharmother
2013QbD principles - next generation of manufacturing processes and personalized medicineBresciani MWorkshop on Advancing capsule dosage forms and technologies, Bologna (IT)other
2013Coalescence and Break-Up in Bubble Columns: Euler-Lagrange Simulations Using a Stochastic ApproachGruber M; Radl S; Khinast J.GChemie-Ingenieur-Technik paper refereed
2013The morphology of spray dried mannitol particles — The vital importance of droplet sizeLittringer E.M; Paus R; Mescher A; Schroettner H; Walzel P; Urbanetz N.APowder technologypaper refereed
2013A multipoint measurement spectrometer for monitoring pharmaceutical processesScheibelhofer O; Sacher S; Menezes J.C; Kerschhaggl P; Khinast J.G NIR 2013 - 16th International Conference on Near Infrared Spectroscopy, La Grande-Motte (FR)poster presentation
2013Coupled CFD-DEM Simulations for Granular Systems in Pharmaceutical ApplicationScharrer G; Radeke C; Jajcevic D; Siegmann E; Khinast J.GAVL User Conference 2013oral presentation
2013Use of Modeling and Simulation in the Life Sciences FieldKhinast J.GGastvortrag am Institut für Technische Chemie und Polymerchemie, Karlsruhe Institute of Technologyother
2013PAT for Pharmaceutical Extrusion: In-line Monitoring of Drug Content with NIRWahl P.R; Markl D; Treffer D; Sacher S; Koscher G; Roblegg E; Khinast J.GSentronic PAT & QbD Meeting 2013, Heidelberg (DE)oral presentation
2013Nano-Extrusion: A One-Step Process for Manufacturing Solid-Nanoparticle Formulations Directly from the Liquid PhaseKhinast J.G; Baumgartner R; Roblegg EAAPS PharmSciTechpaper refereed
2013Soft-sensor assisted dynamic bioprocess control: Efficient tools for bioprocess developmentSagmeister P; Wechselberger P; Jazini M; Meitz A; Langemann T; Herwig CChemical Engineering Sciencepaper refereed
2013The oral cavity as a biological barrier system: Design of an advanced buccal permeability in vitro ModelTeubl B; Absenger M; Fröhlich E; Leitinger G; Zimmer A; Roblegg EEuropean Journal Pharm Biopharmpaper refereed
2013Application of Advanced Simulation Tools for Establishing Process Design Spaces within the Quality-by-Design FrameworkAdam S; Suzzi D; Toschkoff G; Khinast J.GIn: Rex Reklaitis (Ed.), QbD Volume - title to be announced, Chapter 11, Wileybook contribution
2013Interdisziplinäre Forschungs- & Entwicklungsansätze an der Schnittstelle zwischen Pharmazie und TechnikFraser S.D; Klein T.K; Khinast J.GInnovationsdialog Hessen-Österreich, Frankfurt (DE)other
2013Spatially Resolved Monitoring of Powder Mixing Processes via Multiple NIR-ProbesScheibelhofer O; Balak N; Koller D; Khinast J.GPowder Technologypaper refereed
2013Effect of Tablet Coating Parameters: Combining Non-Destructive Measurements and Dissolution TestingToschkoff G; Schinwald C; Markl D; Koller D; Scheideler M; Leitner M; Khinast J.GEuropean Journal of Pharmaceutics and Biopharmaceuticspaper refereed
2013Scale-up effects on flow patterns in high shear mixing of cohesive powdersCavinato M; Artoni R; Bresciani M; Canu P; Santomaso A.CChemical Engineering Sciencepaper refereed
2013Spray drying of aqueous salbutamol sulfate solutions using the Nano Spray Dryer B-90 – The impact of process parameters on particle sizeLittringer E.M; Zellnitz S; Hammernik K; Adamer V; Friedl H; Urbanetz N.ADrying Technologypaper refereed
2013Microstructure of Calcium Stearate Matrix-Pellets: A Function of the Drying ProcessSchrank S; Kann B; Windbergs M; Zimmer A; Khinast J.G; Roblegg EJournal of Pharmaceutical Sciencespaper refereed
2013Computer simulation as quantitative tool for objective quality risk management of a pharmaceutical film coating processStocker E; Toschkoff G; Sacher S; Djuric D; Khinast J.GEUPAT 6: Sxith Pan-European QBD & PAT Science Conference, Portooral presentation
2013Spray Models for Discrete Element Simulations of Particle Coating ProcessesToschkoff G; Just S; Funke A; Djuric D; Knop K; Kleinebudde P; Scharrer G; Khinast J.GChemical Engineering Sciencepaper refereed
2013Collecting, condensing, comprehending and culling spectral data: A pharmaceutical process monitored with SIMCA onlineScheibelhofer O; Hohl R; Salar-Behzadi S; Haack D; Koch K; Kerschhaggl P; Lochmann D; Sacher S; Khinast J.GUmetrics User Meeting 2013, Barcelonaoral presentation
2013Supervisory Control System for Monitoring a Pharmaceutical Hot Melt Extrusion ProcessMarkl D; Wahl R.P; Menezes J.C; Koller D.M; Kavsek B; Francois K; Roblegg E; Khinast J.GAAPS PharmSciTechpaper refereed
2013Large-scale CFD-DEM Simulations of Fluidized Granular SystemsRadeke C; Jajcevic D; Siegmann E.M; Scharrer G; Thiess J; Tatschl R; Khinast J.GParticles 2013, Stuttgart (DE)oral presentation
2013Continuous versus batch manufacturing: comparative assessment applying technical and economic profilingFraser S.D; Dujmovic D; Khinast J.GAcademy of Pharmaceutical Sciences UK PharmSci 2013, Edinburgh, Scotland (UK) oral presentation
2013Modeling of Pharmaceutical Processes in the Context of Continuous ManufacturingKhinast J.GEUPAT 6: Sixth Pan-European QBD & PAT Science Conferenceoral presentation
2013From Multiphase DNS to Large-scale Bioreactor ModelsKhinast J.GProcessNet: Jahrestreffen Reaktionstechnikoral presentation
2013Quality By Design applied to Solid Lipid Nanoparticles: a material science perspectiveMercuri AUKPharmSci; Edinburgh (UK)oral presentation
2013In-line process monitoring of film thickness on pharmaceutical pellets by means of optical coherence tomography as novel PAT technologyMarkl D; Hannesschläger G; Sacher S; Khinast J.G; Leitner MEUPAT 6: Sxith Pan-European QBD & PAT Science Conference; Portopaper refereed
2013Quantitative On-line vs. Off-line NIR Analysis of Fluidized Bed Drying with Consideration of the Spectral BackgroundHeigl N; Koller D; Glasser B.J; Muzzio F; Khinast J.GEuropean Journal of Pharmaceutics and Biopharmaceuticspaper refereed
2013The Effect of Capsule-Filling Machine Vibrations on Average Fill Weight of Capsules.Llusa M; Faulhammer E; Biserni S; Calzolari V; Lawrence S; Scharrer G; Khinast J.GIntnational Journal of Pharmaceuticspaper refereed
2013The morphology and various densities of spray dried mannitolLittringer E.M; Noisternig M.F; Mescher A; Schroettner H; Walzel P; Griesser U.J; Urbanetz N.APowder Technologypaper refereed
2013Soft-sensor assisted dynamic investigation of mixed feed bioprocessesSagmeister P; Kment M; Wechselberger P; Meitz A; Langemann T; Herwig CProcess Biochemistrypaper refereed
2013Inline Monitoring and a PAT Strategy for Pharmaceutical Hot Melt ExtrusionWahl P.R.; Treffer D; Mohr S; Roblegg E; Koscher G; Khinast J.GInternational Journal of Pharmaceuticspaper refereed
2013A dynamic method for the investigation of induced state metabolic capacities as a function of temperatureSagmeister P; Wechselberger P; Meitz A; Langemann T; Herwig CMicrobial Cell Factoriespaper refereed
2013Optimization of Inter-Tablet Coating Uniformity for an Active Coating Process at the Lab and Pilot ScaleJust S; Toschkoff G;Funke A; Djuric D; Khinast J.G; Knop K; Kleinebudde PInternational Journal of Pharmaceuticspaper refereed
2013Application of DEM Simulations and Experimental Studies to Improve the Uniformity of An Active Coating ProcessToschkoff G; Just S; Knop K; Kleinebudde P; Funke A; Djuric D; Scharrer G; Khinast J.GAIChE 2013 Annual Meeting; San Francisco; CA (USA)oral presentation
2013Experimental and theoretical study of tablet flow in a lab scale pan coaterToschkoff G; Boehling P; Johnson D; Sun J; Silverman A; Scharrer G; Khinast J.G; Rajnak PAIChE 2013 Annual Meeting; San Francisco; CA (USA)oral presentation
2013Raising efficiency in early stage developments by using the new Nano ABC nozzle for EUDRAGIT® coatingsDassinger T; Breuer A; Toschkoff G; Scharrer G; Forlizzi I; Gerstner SAAPS Annual Meeting 2013; San Antonio (USA)poster presentation
2013Impact of spray drying on the cellular properties of Bifidobacterium bifidum BB-12Salar-Behzadi S; Wu S; Toegel S; Hofrichter M; Altenburger I; Stummer S; Unger F; Wirth M; Viernstein HFood Research Internationalpaper refereed
2013The Effect of the Ratio between the Powder Bed’s Height and the Length of the Dosing Chamber and the Speed of Capsule Filling on Plug Density and Capsule Weight VariabilityBresciani M; Llusa M; Faulhammer E; Scharrer G; Lawrence S; Biserni S; Calzolari V; Khinast J.GAAPS 2013 Annual Meeting and Exposition; San Antonio (USA)poster presentation
2013Applying economic analysis in the evaluation of batch versus continuous manufacturing options for oral solid dosage formsFraser S.D; Dujmovic D; Khinast J.GAIChE 2013 Annual Meeting; San Francisco; CA (USA)oral presentation
2013Manufacturing low fill weight capsules using a nozzle dosator capsule filling machineLlusa M; Faulhammer E; Fink M; Biserni S; Calzolari V; Lawrence S; Bresciani M; Scharrer G; Khinast J.GAIChE 2013 Annual Meeting; San Francisco; CA (USA)oral presentation
2013A One-Step Process to Manufacture Solid Nano-Particle Formulations Directly from the Liquid PhaseKhinast JGAIChE Annual Meeting 2013, San Francisco (USA)oral presentation
2013Process Understanding in the Context of QbD:
Current Approaches and Desired State
Khinast J.GAIChE 2013 Annual Meeting; San Francisco; CA (USA)oral presentation
2013In-line Monitoring of a Fluid-bed Coating Process with Optical Coherence TomographySacher S; Markl D; Hannesschläger G; Leitner M; Khinast J.G AIChE 2013 Annual Meeting; San Francisco; (USA)poster presentation
2013Large-Scale Coupled CFD-DEM Simulations of Fluidized Granular SystemsRadeke C; Jajcevic D; Siegmann E; Toschkoff G; Scharrer G; Khinast J.GAIChE 2013 Annual Meeting; San Francisco; CA (USA)oral presentation
2013Modeling and Simulation in Biotechnological EngineeringPrieling D; Scharrer GBiotechnologie - Aspekte der Fermentationstechnologie; ESN Heidelberg (DE)oral presentation
2013Experimental characterization and modeling of twin-screw extruder elements for pharmaceutical hot melt extrusionEitzlmayr A; Khinast J.G; Hörl G; Koscher G; Reynolds G; Huang Z; Booth J; Shering PAIChE Journalpaper refereed
2013The effect of process parameters and powder properties on low dose dosator capsule fillingLlusa M; Faulhammer E; Fink M; Lawrence S; Biserni S; Calzolari V; Khinast J.GDDL 24; 2013; Edinburgh (UK)poster presentation
2013The effect of process parameters and powder properties on low dose dosator capsule fillingLlusa M; Faulhammer E; Fink M; Lawrence S; Biserni S; Calzolari V; Khinast J.GDrug Delivery to the Lungs DDL 24; Edinburgh (UK)oral presentation
2013Mathematical Modeling of the Coating ProcessToschkoff G; Khinast J.GInternational Journal of Pharmaceutics paper refereed
2013Titanium dioxide nanoparticles and the oral uptake-routeFröhlich E; Teubl B; Roblegg EJournal BioNanoMaterialspaper refereed
2013Large-scale CFD-DEM Simulations of Fluidized Granular SystemsJajcevic D; Siegmann E; Radeke C; Khinast J.GChemical Engineering Sciencepaper refereed
2013Optical coherence tomography for non-destructive analysis of coatings in pharmaceutical tabletsMarkl D; Hannesschläger G; Sacher S; Leitner M; Khinast J.GProc. SPIEproceedings
2013Hot Melt Extrusion as a Continuous Pharmaceutical Manufacturing ProcessTreffer D; Wahl P; Markl D; Koscher G; Roblegg E; Khinast J.GMelt Extrusion: Materials; Technology and Product Designbook contribution
2013Advanced formulations for paediatric drug therapyD. Lopes K. Becker D. Haack A. Zimmer S. Salar-Behzadi5th EUPFI Conference: Formulating better medicines for children Barcelona (SP)poster presentation
2013Advanced structuring of lipids for controlled drug release: polymorphic crystallizations and curing effectsLopes D; Becker K; Faulhammer E; Haack D; Lochmann D; Khinast J; Zimmer A; Salar-Behzadi SEmployee meetingOral presentation
2013Characterization of a laboratory-scale container for freezing protein solutions with detailed evaluation of a freezing process simulation.Roessl U; Jajcevic D; Leitgeb S; Khinast JG; Nidetzky BJournal of Pharmaceutical Sciencespaper refereed
2012Hydrophobic Patches Promote Attraction - Why and How and Do They Really?Brunsteiner M2012 Workshop on Protein Aggregation and Immunogenicity
Breckenridge Colorado (USA)
poster presentation
2012High-throughput assessment of temperature-induced aggregation propensities in formulation developmentAblinger E; Leitgeb S; Zimmer AWorkshop on Protein Aggregation and Immunogenicity Breckenridge (USA) poster presentation
2012Stability of L-Lactic Dehydrogenase in a Lab-Scale Freezing ContainerRößl U; Jajcevic D; Leitgeb S; Nidetzky BWorkshop on Protein Aggregation and Immunogenicity Breckenridge (USA) poster presentation
2012Engineering of Aerococcus viridans l-lactate oxidase for site-specific PEGylation: Characterization and selective bioorthogonal modification of a S218C mutantUnterweger B; Stoisser T; Leitgeb S; Birner-Grünberger R; Nidetzky BBioconjugate Chemistrypaper refereed
2012Prediction of drug-packaging interactions via molecular dynamics (MD) simulationsFeenstra P; Brunsteiner M; Khinast J.GInternational Journal of Pharmaceuticspaper refereed
2012The onset of fragmentation in binary liquid drop collisionsPlanchette C; Lorenceau E; Brenn GJournal of Fluid Mechanicspaper refereed
2012Continuous Sonocrystallization of Acetylsalicylic Acid (ASA): Control of Crystal Size Eder R.J.P; Schrank S; Besenhard M.O; Roblegg E; Gruber-Woelfler H; Khinast J.GCrystal Growth & Designpaper refereed
2012Optimization of processing by characterizing critical protein powder parametersWahl V; Piller M; Leitgeb S; Khinast J.G2012 CPPR Freeze Drying of Pharmaceuticals & BiologicsBreckenridge Co (USA)poster presentation
2012Investigation of particle flow pattern in an innovative fluid bed equipmentSalar-Behzadi S; Eitzlmayr A; Leadbeater T; Parker D; Seville J; Viernstein H
Khinast JG
20th Intenational Congress of Chemical and Process Engineering (CHISA 2012) Prag (CZ)poster presentation
2012Surface optimized model carrier systems for pulmonary drug deliveryZellnitz S; Redlinger-Pohn J.D; Schröttner H; Urbanetz N.A20th Intenational Congress of Chemical and Process Engineering (CHISA 2012) Prague (CZ)poster presentation
2012Controlling tribo-charge arising on pharmaceutical powders by controlling the influencing factorsKarner S; Urbanetz N.A20th Intenational Congress of Chemical and Process Engineering (CHISA 2012) Prague (CZ)oral presentation
2012Computer simulation of particle compaction using the finite element method and contact pairsScharrer G; Khinast J.G6th Annual PSSRC Symposium 2012, Lisbon (PT)oral presentation
2012Non-native aggregation of recombinant human granulocyte-colony stimulating factor under simulated process stress conditionsRoessl U; Wiesbauer J; Leitgeb S; Birner-Gruenberger R; Nidetzky BBiotechnology Journalpaper refereed
2012Modeling of aerated stirred tanks with shear-thinning power law liquidsSungkorn R; Derksen J.J; Khinast J.GInternational Journal of Heat & Fluid Flowpaper refereed
2012Flow and mixing of granular material over a single bladeRadl S; Brandl D; Heimburg H; Glasser B.J; Khinast J.GPowder Technologypaper refereed
2012Integrating Continuous Crystallization into Continuous SynthesisBeckmann W; Khinast JG; Severins CProcessNet-Jahrestagung und 30. DECHEMA-Jahrestagung der Biotechnologen 2012, Karlsruhe (DE)oral presentation
2012Application of DEM spray models for the optimization of tablet coating processes. Just S; Toschkoff G; Funke A; Djuric D; Khinast J.G; Knop K; Kleinebudde P20th Intenational Congress of Chemical and Process Engineering (CHISA 2012), Prague (CZ)poster presentation
2012(Multiawesome) Multispectral, Multiprobe MonitoringScheibelhofer O; Hohl R; Salar-Behzadi S; Haack D; Koch K; Kerschhaggl P; Sacher S; Menezes J.C; Khinast J.GTagung der österreichischen physikalischen Gesellschaft, Graz (AT)oral presentation
2012Employing disulphide bond mapping to investigate the aggregation mechanism of rhG-CSFRößl U; Wiesbauer J; Leitgeb S; Nidetzky B10th Austrian Proteomic Research Symposium Graz (AT)poster presentation
2012The onset of fragmentation in binary liquid drop collisionsPlanchette C; Lorenceau E; Brenn G12th Triennial International Conference on Liquid Atomization and Spray Systems (ICLASS 2012), Heidelberg (DE)oral presentation
2012Glass beads as alternative carrier systems for dry powder inhalersZellnitz S; Redlinger-Pohn J.D; Schroettner H; Kappl M; Urbanetz N.A7th International Conference for Conveying and Handling of Particulate Solids (CHOPS2012). Friedrichshafen (DE)oral presentation
2012Calcium Stearate Pellets Loaded with Morphine Derivates: Impact of the Granulation Liquid Schrank S; Tockner M; Zimmer A; Roblegg E9th Central European Symposium on Pharmaceutical Technology (CESPT), Dubrovnik (KR)poster presentation
2012Intelligent processes in the pharmaceutical industry: a roadmap towards SMART pharmaLeitgeb S; Weber NiKnow 2012, Graz (AT)oral presentation
2012DNS of Bubble SwarmsKhinast JGISCRE 22, Maastricht (NE)oral presentation
2012Funktionalisierte mesoporöse Monolithen für kontinuierliche Ringspalt-ElektrochromatographieBraunbruck M.G; Feenstra P; Gruber-Wölfler H; Khinast J.G ProcessNet, Karlsruhe (DE)poster presentation
2012Structure and mechanism of human UDP-xylose synthase: evidence for a promoting role of sugar ring distortion in a three-step catalytic conversion of UDP-glucuronic acidEixelsberger T; Sykora S; Egger S; Brunsteiner M; Kavanagh K.L; Oppermann U; Brecker L; Nidetzky BJournal of Biological Chemistrypaper refereed
2012Numerical Simulation of Pharmaceutical Tablet Coating Processes: First Steps Towards an in-silico Design SpaceToschkoff G; Suzzi D; Adam S; Khinast J.GPharmaceutical Technology Europepaper refereed
2012Scale-up of Capsule Filling Operations Using a Nozzle-Dosator Machine.Llusa M; Faulhammer E; Biserni S; Calzolari V; Lawrence S; Scharrer G; Khinast J.GAIChE Annual Meeting 2012, Pittsburgh (USA)oral presentation
2012Optimization of Inter-Tablet Coating Uniformity in an Active Coating ProcessJust S; Toschkoff G; Funke A; Djuric D; Scharrer G; Khinast J.G; Knop K; Kleinebudde PAAPS Annual Meeting 2012, Chicago (USA)poster presentation
2012Application of Enhanced DEM Simulations for the Improvement of a Given Tablet Coating Process Toschkoff G; Just S; Scharrer G; Knop K; Kleinebudde P; Djuric D; Altmeyer A; Funke A; Khinast J.GAIChE Annual Meeting 2012, Pittsburgh (USA)oral presentation
2012Control, Design and Applications of a Seeded Continuously Operated Crystallizer for Active Pharmaceutical IngredientsBesenhard M.O; Eder R.L.P; Scharrer G; Khinast J.GCGOM10 2012oral presentation
2012Fluid bed in a FlashScheibelhofer O; Hohl R; Salar-Behzadi S; Haack D; Koch K; Kerschhaggl P; Sacher S; Menezes J; Khinast J.GAIChE Annual Meeting 2012, Pittsburgh (USA)oral presentation
2012Simulation approaches for elastic and plastic deformationBoetker JP; Scharrer G; Khinast JG; Norfeldt L; Soegaard SV; Garnaes J; Sonnergaard J; Rantanen JAAPS Annual Meeting 2012, Chicago (USA)oral presentation
2012A Pharmaceutical Engineering Process/Product Life-Cycle Approach to Drug Product Development and ManufacturingMenezes JC; Sacher S; Scharrer G; Leitgeb S; Voura C; Fraser SD; Khinast JGAIChE Annual Meeting 2012, Pittsburgh (USA)oral presentation
2012Coupled CFD and DEM Simulation of Fluid-Granular Systems Jajcevic D; Radeke C; Scharrer G; Khinast JGAIChE Annual Meeting 2012, Pittsburgh (USA)oral presentation
2012Towards a Refined Theory for Liquid Transfer in Dense and Dilute Particle Beds Radl S; Girardi M; Radeke C; Khinast J.G; Sundaresan SAIChE Annual Meeting 2012, Pittsburgh (USA)oral presentation
2012PAT for Pharmaceutical Extrusion Monitoring and Supervisory ControlWahl P; Markl D; Treffer D; Menezes J; Koscher G; Roblegg E; Khinast JGAIChE Annual Meeting 2012, Pittsburgh (USA)oral presentation
2012Evaluating the effects of buffer conditions and extremolytes on thermostability of granulocyte colony-stimulating factor using high-throughput screening combined with design of experimentsAblinger E; Hellweger M; Leitgeb S; Zimmer AInternational Journal of Pharmaceuticspaper refereed
2012Carrier particle engineering for pulmonary drug delivery via spray dryingUrbanetz NA; Littringer EM1st annual symposium of drug delivery systems Shenzen (VRC)oral presentation
2012Schmelzextrusion zur Herstellung pharmazeutischer DarreichungsformenKoscher G21. Leobener Kunststoff Kolloqium: Mit Compoundieren zum Erfolg, Leoben (AT)oral presentation
2012Homogene Produkteigenschaften in der Sprühtrocknung durch laminare RotationszerstäubungMescher A; Littringer E.M; Paus R; Urbanetz N.A; Walzel PChemie Ingenieur Technikpaper refereed
2012Transition of liquid marble impacts onto solid surfacesPlanchette C; Lorenceau E; Biance A.LEuro Physics Letterspaper refereed
2012Demonstration of a Pharmaceutical Hot Melt Extrusion Process with SIPATMarkl DIFPAC 2012 Twenty-Sixth International Forum. Process Analytical Technology, Baltimore (USA)oral presentation
2012Surface wave on a particle raftPlanchette C; Lorenceau E; Biance A.LSoft Matterpaper refereed
2012Detailed Analysis of Air Flow and Spray Loss in a Pharmaceutical Coating ProcessToschkoff G; Suzzi D; Tritthart W; Reiter F; Schlingmann M; Khinast J.GAIChE Journal paper refereed
2012DEM simulation of continuous tablet coating: Effects of tablet shape and fill level on inter-tablet coating variability Suzzi D; Toschkoff G; Radla S; Machold D; Fraser S.D; Glasser B.J; Khinast J.GChemical Engineering Sciencepaper refereed
2012Effect of process variables on the Small and Wide Angle X-Ray Scattering (SWAXS) patterns of powders, granules and pharmaceutical tabletsHodzic A; Llusa M; Heigl N; Tritthart W; Fraser S.D; Laggner P; Khinast J.GPowder Technologypaper refereed
2012The influence of droplet size on the crystallization behavior of aqueous mannitol solutions during spray dryingLittringer E.M; Mescher A; Paus R; Luger T; Schröttner H; Walzel P; Urbanetz N.A8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical
Technology, Istanbul (TC)
poster presentation
2012Lipophilic Calcium Stearate Pellets Produced via HME: Impact of Plasticizers on the In-Vitro ReleaseJedinger N; Koscher G; Khinast J.G; Roblegg E8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical
Technology, Istanbul (TC)
poster presentation
2012Rational Design of Lipophilic Calcium Stearate Pellets Produced via HMEJedinger N; Fuchs K; Koscher G; Khinast JG; Roblegg E8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical
Technology, Istanbul (TC)
poster presentation
2012Understanding the effects of powder and wall material properties on weight variability during capsule fillingFaulhammer E; Llusa M; Scharrer G; Khinast J.G8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical
Technology, Istanbul (TC)
poster presentation
2012Full PAT Solution for Real-Time Process Control of a Pharmaceutical Hot Melt Extruder (HME)Wahl P; Markl D; Koscher G; Khinast J.G8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical
Technology, Istanbul (TC)
oral presentation
2012Mucoadhesive Pellets for Buccal Application: An Alternative to the Oral RouteSchrank S; Lesky L; Stratil D; Fröhlich E; Roblegg EAPV World Meeting, Istanbul (TC) poster presentation
2012The Large Impact of Drying on API Release from Wet-Granulated CalciumStearate PelletsSchrank S; Glasser B.J; Zimmer A; Khinast J.G; Roblegg EAPV World Meeting, Istanbul (TC) poster presentation
2012Small- and Wide-Angle X-Ray Scattering (SWAXS) for Quantification of Aspirin Content in a Binary Powder MixtureHodzic A; Llusa M; Fraser S.D, Scheibelhofer O; Koller D.M; Reiter F; Laggner P; Khinast J.GJournal of Pharmaceuticspaper refereed
2012A new Textile-Based Approach to Assess the Antimicrobial Activity of VolatilesLiebminger S; Aichner M; Oberauner L; Fürnkranz MTextile Research Journalpaper refereed
2012Continuous Manufacturing in Secondary Pharmaceutical ProductionMenezes J; Fraser S; Khinast J.GWorldMeeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul (TC)oral presentation
2012Chiral separation of cathinone derivatives used as recreational drugs by HPLC-UV using a Chiralpak® AS-H column as stationary phaseMohr S; Taschwer M; Schmid MGChirality paper refereed
2012Influence of process parameters on the D-mannitol particle formation during spray dryingLittringer E.M; Mescher A; Schröttner H; Walzel P; Urbanetz A 12th International Conference on Pharmacy and Applied Physical Chemistryoral presentation
2012Spray drying of mannitol as a drug carrier – The impact of process parameters on the product propertiesLittringer E.M ;Mescher A; Eckhard S; Schroettner H; Langes C; Fries M; Grieser U; Walzel P; Urbanetz N.ADrying Technologypaper refereed
2012Spray-dried mannitol carrier particles with optimized surface properties – The influence of carrier surface roughness and shapeLittringer E.M; Mescher A; Schroettner H; Achelis L; Walzel P; Urbanetz N.AEuropean Journal of Pharmaceutical Sciencespaper refereed
2012Mercury Intrusion Porosimetry – A powerful method for the characterisation of spray dried productsNoisternig M; Littringer E.M; Urbanetz N.A; Grieser USpray 2012 Berlin (D)oral presentation
2012Investigating freeze and thaw behavior of protein solutions using a lab-scale freeze container Rößl U; Jajcevic D; Leitgeb S; Nidetzky B2012 AAPS National Biotechnology Conference San Diego (USA)poster presentation
2012Characterizing critical protein powder parameters for optimization of further processingWahl V
Leitgeb S.; Khinast J.
8. Minisymposium der Verfahrenstechnik Linz (A)poster presentation
2012Lösungsmitteleinfluss auf das Filtrationsverhalten organischer FeststoffpartikelGursch J; Dujmovic D; Khinast J8. Minisymposium der Verfahrenstechnik, Linz (A)poster presentation
2012Modeling of Co-Rotating Twin Screw ExtrusionHörl G; Windhab S; Koscher G; Khinast J.G8. Minisymposium der Verfahrenstechnik, Linz (A)poster presentation
2012Monitoring of a Water spray Process with NIR and comparison with DEM SimulationHohl R8. Minisymposium der Verfahrenstechnik, Linz (A)poster presentation
2012PAT Solution for Inline Content Homogeneity Monitoring with NIR for Pharmaceutical Hot Melt ExtrusionWahl P; Markl D; Koscher G; Khinast J.G8. Minisymposium der Verfahrenstechnik, Linz (A)oral presentation
2012The Correlation Between Powder Properties, Nozzle Material And Capsule WeightFaulhammer E; Llusa M; Scharrer G; Khinast J.G8. Minisymposium der Verfahrenstechnik, Linz (A)poster presentation
2012Including Spray Models in DEM Simulations of Tablet CoatingToschkoff G; Just S; Knop K; Kleinebudde P; Funke A; Altmeyer A; Khinast J.G8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical
Technology, Istanbul (TC)
poster presentation
2012Investigating freeze and thaw behavior of protein solutions using a lab-scale freeze container Rößl U; Jajcevic D; Leitgeb S; Nidetzky B9th International Conference on Protein Stabilisation Lissabon (Portugal)oral presentation
2012Ibuprofen-Loaded Calcium Stearate Pellets: Drying-Induced Variations in Dosage Form PropertiesSchrank S; Hodzic A; Zimmer A; Glasser B.J; Khinast J.G; Roblegg EAAPS PharmSciTechpaper refereed
2012Continuous Pharmaceutical Manufacturing with Hot Melt ExtrusionMarkl D; Wahl V; Khinast J.GEuPAT 5, Continuous Innovation in Process Analytics & Control, Ghent (B)oral presentation
2012Comparison between Multipoint NIR Spectroscopy and DEM Simulations via a Water Spray ProcessHohl REuPAT 5; Continuous Innovation in Process Analytics and Control; Ghent (B)poster presentation
2012Depth of Scrutiny for Monitoring Powder flow via Near-Infrared SpectroscopyScheibelhofer O; Koller D; Khinast J.GEuPAT 5; Continuous Innovation in Process Analytics and Control; Ghent (B)poster presentation
2012Developing a PAT Strategy for Pharmaceutical Hot Melt ExtrusionWahl P; Koscher G; Khinast J.GEuPAT 5; Continuous Innovation in Process Analytics and Control; Ghent (B)poster presentation
2012Continuous Powder Flow Monitoring via Near-Infrared Hyperspectral ImagingScheibelhofer O; Koller D; Kerschhaggl P; Khinast J.GI2MTC 2012; IEEE International Instrumentation and Measurement Technology Conference; Graz (A)poster presentation
2012Potential of Raman Spectroscopy for Evaluating Crushing Strength of TabletsHeigl N; Hodzic A; Llusa M; Tritthart W; Reiter F; Fraser S.D; Laggner P; Khinast J.GJournal of Pharmaceutical Innovationpaper refereed
2012Ibuprofen-loaded Calcium Stearate Pellets: Pellet Characteristics in Dependence upond the Drying ConditionsSchrank S; Glasser B.J; Zimmer A; Khinast J.G; Roblegg EPhandta 12; Graz (A)poster presentation
2012Towards simulation of compaction processesBoetker J.P; Scharrer G; Khinast J.G; Soegaard S.V; Garnaes J; Sonnergaard J; Rantanen JThe 2nd Electronic conference on Pharmaceutical Sciencesoral presentation
2012Enantioseparation of legal highs derived from cathinone using a Chrialpak AS-H column in normal phase HPLCMohr S38th International Symposium on High Performance Liquid Phase Separations and Related Technique; Anaheim (USA)poster presentation
2012Kunststoff granulieren und/oder pelletieren?Muerb RChemie Ingenieur Technikother
2012Chiral separatin of cathinone derivatives used as recreational drugs by cyclodextrin-modified capillary electrophoresisMohr S; Pilaj S; Schmid MGElectrophoresis paper refereed
2012Water Spray Process Online Monitored with Multipoint NIR and Compared with DEM SimulationHohl R; Heigl N; Scheibelhofer O; Koller D; Radeke C; Sacher S; Menezes J; Khinast J.GXIII Chemometrics in Analytical Chemistry; Budapest (HU)poster presentation
2012Euler-Lagrange modeling of a gas-liquid stirred reactor with consideration of bubble breakage and coalescenceSungkorn R; Derksen J.J; Khinast J.GAIChE Journal paper refereed
2012Chiral separation of α-hydroxy acids by capillary electrochromatography using the cathodic detergent CTAB as mobile phase additive to speed up analysis timeMohr S; Sepic G; Schmid M.CCroatica Chemica Actapaper refereed
2012Wet granular flows in a bladed mixer: Experiments and simulations of monodisperse spheres Remy B; Khinast J.G; Glasser B.JAIChE Journalpaper refereed
2012Particle formation of mannitol during spray drying - a scale-up problemLittringer E.M; Mescher A; Paus R; Walzel P; Urbanetz N.ASPP 1423 "Prozess-Spray" Jahrestreffen; Darmstadt (DE) oral presentation
2012Achieving Specification Data by Application of Process Analytical TechnologySacher S; Khinast J.GInforma; Setting Specifications; Berlin (DE)oral presentation
2012The Influence of Process Parameters on the Properties of PLGA-Microparticles Produced by the Emulsion Extraction MethodKiss N; Brenn G; Suzzi D; Scheler S; Jennewein H; Wieser J; Khinast J.GAIChE Journalpaper refereed
2012Mechanical modification of glass beads used as model carrier particles in dry powder inhalersZellnitz S; Redlinger-Pohn J.D; Schroettner H; Urbanetz N.ADrug Delivery to the Lungs - DDL23; Edinburgh (UK)poster presentation
2012Spray Drying of Aqueous Salbutamo Sulfate Solutions Using the Nano Spray Dryer B-90 – The Impact of Process Parameters on Particle SizeLittringer E.M; Zellnitz S; Hammernik K; Friedl H; Urbanetz N.ADrug Delivery to the Lungs; 2012; Edinburgh (UK)poster presentation
2012Analysis of drug-packaging interactions via molecular dynamics (MD) simulationFeenstra P; Brunsteiner M; Khinast J.GExtractables & Leachables Europeoral presentation
2012Chiral separation of new cathinone- and amphetamine-related designer drugs by gas chromatography–mass spectrometry using trifluoroacetyl-L-prolyl chloride as chiral derivatization reagentMohr S; Weiß J.A; Spreitz J; Schmid M.GJournal of Chromatographypaper refereed
2012DOE-Based based CFD Optimization of Pharmaceutical Mixing ProcessesHörmann T; Suzzi D; Adam S; Khinast J.GJournal of Pharmaceutical Innovationpaper refereed
2012Ibuprofen-Loaded Calcium Stearate Pellets: Drying-Induced Variations in Dosage Form Properties  Schrank S; Hodzic A; Zimmer A; Glasser B. J; Khinast J; Roblegg EAAPS PharmSciTechpaper refereed
2011Mixing and Dissolution Processes of Pharmaceutical Bulk Materials in Stirred Tanks: Experimental and Numerical InvestigationsHörmann T; Suzzi D; Khinast J.GIndustrial & Engineering Chemistry Researchpaper refereed
2011Studien zur Ausbildung der Partikelmorphologie im Sprühtrocknungsprozess zur Steuerung der Leistungsmerkmale von PulverinhalatenLittringer E; Urbanetz N.A; Schröttner H; Walzel P; Mescher A; Maas A.A; Paus RBerichterstattung und Begutachtung zur zweiten Periode des SPP 1423 „Prozess-Spray“ Frankfurt (D)poster presentation
2011Tailoring the performance of carrier based dry powder inhalates by surface modification of the carrier using spray dryingUrbanetz N.A; Littringer E.MBerichterstattung und Begutachtung zur zweiten Periode des SPP 1423 „Prozess-Spray“ Frankfurt/Main (D)oral presentation
2011Carrier particle engineering for pulmonary drug delivery via spray dryingUrbanetz N.A;
Littringer E.M.
Pharmazeutisches Kolloquium - Uni Innsbruck (A)oral presentation
2011Quantitative Monitoring of Batch and Continuous Powder Mixing Processes with Spatially Resolved Spectroscopic PAT-ToolsKoller D; Balak N; Scheibelhofer O; Khinast J.GIFPAC - Process Analytical Technology, Baltimore (USA)oral presentation
2011Validation of the freezing process of bio-pharmaceuticals in a scale-down containerLeitgeb S; Iannuccelli M; Sirnik B; Suzzi D; Khinast J.G; Rinderhofer APepTalk 2011, San Diego (USA)oral presentation
2011Validation of the freezing process of bio-pharmaceuticals in a scale-down container Leitgeb S; Iannuccelli M; Sirnik B; Suzzi D; Khinast J.G; Traußnig A; Rinderhofer APepTalk 2011 San Diego (USA)poster presentation
2011Printable medicines: A microdosing device for producing personalised medicinesVoura C; Schroedl N; Gruber M; Strohmeier D; Eitzinger B; Bauer W; Brenn B; Khinast J.G; Zimmer APharmaceutical Technology Europepaper refereed
2011Aggregation of Recombinant Human Granulocyte-Colony Stimulating Factor under Process ConditionsRößl U; Wiesbauer J; Leitgeb S; Nidetzky BXV School of Pure and Applied Biophysics, Venedig (I)poster presentation
2011Sprühtrocknungsverfahren zur Erzeugung inhalierbarer PulverUrbanetz NA; Littringer EMSprühtrocknung zur Herstellung fester Arzneiformen, Fulda (D)oral presentation
2011Interactions of the AT1 Antagonist valsartan with dipalmitoyl-phosphatidylcholine bilayersPotamitis C; Chatzigeorgiou P; Siapi E; Viras K; Mavromoustakos T; Hodzic A; Pabst G; Cacho-Nerin F; Laggner P; Rappolt MBiochimica et Biophysica Acta 1808paper refereed
2011Seed Loading Effects on the Mean Crystal Size of Acetylsalicylic Acid in a Continuous-Flow Crystallization DeviceEder R.J.P; Schmitt E.K; Grill J; Radl S; Gruber-Woelfler H; Khinast J.GCrystal Research and Technologypaper refereed
2011The impact of electrostatic charge in pharmaceutical powders with specific focus on inhalation-powdersKarner S; Urbanetz N.AJournal of Aerosol Science paper refereed
2011A deeper understanding of tablet coating processes through Discrete Element Method simulationsToschkoff G; Suzzi D; Khinast JGEDEM Conference, Glasgow (UK)oral presentation
2011Headspace-SPME-GC/MS as a simple cleanup tool for sensitive 26-diisopropylphenol analysis from lipid emulsions and adaptable to other matricesPickl K.E; Adamek V; Gorges R; Sinner F.MJournal of Pharmaceutical and Biomedical Analysispaper refereed
2011Use of Computer Simulations as Process Characterization Tool for Generation of Mechanistic Process Understanding within the Quality by Design EnvironmentSuzzi D; Adam S; Iannuccelli M; Toschkoff G; Radeke C; Khinast JG; Radl SEUROPACT 2011 - 2nd European Conference on Process Analytics and Control Technology, Glasgow (UK)oral presentation
2011Continuous Manufacturing and Hot Melt ExtrusionRoblegg E; Koscher G; Hirmann K; Khinast JG; Jäger EAPV Experts' Workshop on Hot Melt Extrusion, Tarrytown (USA)oral presentation
2011Spatially Resolved Process Monitoring with Spectroscopic PAT-ToolsKoller D; Scheibelhofer O; Fraser S; Khinast JGEUROPACT 2011 - 2nd European Conference on Process Analytics and Control Technology, Glasgow (UK)oral presentation
2011Effect of Blade Angle and Particle Size on Powder Mixing Performance in a Rectangular Box Siraj M.S; Radl S; Glasser B.J; Khinast J.GPowder Technologypaper refereed
2011How much sterility is possible? New concepts for clean room environments based on plant-associated bacteria Liebminger S; Aichner M; Oberauner L; Berg G11th Conference on Bacterial Genetics and Ecology - BAGECO11, Corfu (GR)poster presentation
2011Use of Advanced Quality by Design Concepts and Tools in Generic Drug DevelopmentStumptner W; Adam S; Koller D; Suzzi D; Khinast J.G1st Open Forum on Pharmaceutics and Biopharmaceutics Supergenerics, Budapest (HU)oral presentation
2011Multi-Phase and Multi-Scale Simulation in the Pharmaceutical IndustrySuzzi DSIMNET Days 2011, Leoben (A)oral presentation
2011Biotransformations in microstructured reactors: more than flowing with the stream? Bolivar J.M; Wiesbauer J; Nidetzky BTrends in Biotechnologypaper refereed
2011SAXS and SWAXS/DSC Laboratory Pharmaceutical ApplicationsHodzic AWorkshop on SAXS Laboratory Practice, New Approaches and Integrated Techniques, Graz (A)oral presentation
2011Einflussgrößen auf die triboelektrische Aufladung von Mannitol als Trägerstoff für Dry Powder InhalerUrbanetz N.A; Karner S7. Minisymposium VT Graz (A)poster presentation
2011Influence of droplet size on the crystallization behaviour of aqueous D-mannitol solutions during spray dryingLittringer E; Schröttner H; Walzel P; Mescher A; Maas A; Paus R7. Minisymposium VT Graz (A)oral presentation
2011Influence of surface roughness on the quality attributes of dry powder inhalers Littringer E; Urbanetz N.ASummerschool/workshop "Rheologie und Phasengrenzen bei der Zerstäubung" Bremen (D)oral presentation
2011API-Kristallisation in einem RohrBesenhard M; Schrank S; Gruber-Wölfler H; Khinast JG7. Minisymposium VT, Graz (A)poster presentation
2011Application of Process Analytical Technology (PAT) in Pharmaceutical ProductionWahl P; Scheibelhofer O; Koller D; Khinast JG7. Minisymposium VT, Graz (A)oral presentation
2011Investigation of the interaction between drug product solutions and packaging materialsM. Brunsteiner M. Eichinger H. Gruber-Wölfler J.G. Khinast P. Feenstra.7. Minisymposium VT Graz (A)poster presentation
2011Theory and Application of Population Balance Equations in Chemical EngineeringBesenhard M; Eitzlmayer A; Suzzi D; Khinast JG; Eder R7. Minisymposium VT, Graz (A)oral presentation
2011Parcel-Based Approach for the Simulation of Gas-Particle FlowsRadeke C; Khinast JG8th International Conference on CFD in Oil & Gas, Metallurgical and Process Industries, Trondheim (N)oral presentation
2011Calcium-Stearate Micro-pellets: Impact of Drying on Final Pellet CharacteristicsSchrank S; Khinast JG; Roblegg E; Reischl D; Zimmer A2011 PharmSciFair, Prag (CZ)poster presentation
2011Continuous Flow Crystallization of Active Pharmaceutical IngredientsSchrank S; Roblegg E; Besenhard M; Gruber-Wölfler H; Khinast JG; Eder R; Grill J; Schmitt E2011 PharmSciFair, Prag (CZ)poster presentation
2011Development of Dexamethasone-loaded Nanostructured Lipid Carriers (NLC) for NebulizationWeber S.2011 PharmSciFair, Prag (CZ)poster presentation
2011Quality by Design based Study on the Optimization of a Tablet FormulationReischl D; Adam S; Windhaber S; Roblegg E; Khinast J.G2011 PharmSciFair, Prag (CZ)oral presentation
2011Itraconazole-loaded Nanostructured Lipid Carriers (NLC) for pulmonary application in falconsWeber S.PharmSciFair Prag (Tschechische Republik)poster presentation
2011Preparation of Fast Disintegrating Micro-Pellets using Ludiflash® and Functional AdditivesSchrank S; Roblegg E; Heidinger P2011 PharmSciFair, Prag (CZ)poster presentation
2011Transport Studies of Polystyrene Nanoparticles across the Buccal MucosaRoblegg E; Teubl B; Fröhlich E; Zimmer A2011 PharmSciFair, Prag (CZ)poster presentation
2011The 3-His iron center – a distinct motif of catalytic function in non-heme metal dependent enzymesLiebminger S; Nidetzky B; Straganz GTransition metals in biochemistry, Norwich (UK)oral presentation
2011The impact of spray drying outlet temperature on the particle morphology of mannitolMaas S.G; Schaldach G; Littringer E.M; Mescher A; Ulrich J; Griesser U.J; Doris E; Braun D.E; Peter E; Walzel P.E; Nora A; Urbanetz N.APowder Technologypaper refereed
2011Non-Native Aggregation of rhG-CSF under Simulated Process ConditionsRößl U; Wiesbauer J; Leitgeb S; Birner-Grünberger R; Nidetzky B2011 Colorado Protein Stability Conference Breckenridge (CO USA)oral presentation
2011Freezing and Thawing of Protein Solutions – Introducing a Lab-Scale Freezing Container Rößl U; Leitgeb S; Nidetzky B2011 Colorado Protein Stability Conference Breckenridge (USA)poster presentation
2011Influence and comparison of accelerated stress conditions on human growth hormoneWiesbauer J; Massimiliano M; Nidetzky B6th DocDay Graz (A)poster presentation
2011Investigation of tablet coating processes using Discrete Element Method simulationsToschkoff G; Suzzi D; Just S; Knop K; Kleinebudde P; Khinast JG7. Minisymposium VT, Graz (A)oral presentation
2011Modeling of Pharmaceutical Hot Melt ExtrusionEitzlmayr A; Suzzi D; Koscher G; Shering P; Reynolds G; Booth J; Khinast JG7. Minisymposium VT, Graz (A)poster presentation
2011Formation of O/W emulsions by static mixers for pharmaceutical applicationsKiss N; Brenn G; Pucher H; Wieser J; Scheler S; Jennewein H; Suzzi D; Khinast J.GChemical Engineering Sciencepaper refereed
2011Numerical Simulation of Freeze-Thaw Biopharmaceutical ProcessIannuccelli M; Suzzi D; Sirnik B; Rinderhofer A; Khinast J.GChemical Engineering Transactionspaper refereed
2011Development of Sustained-Release Lipophilic Calcium Stearate Pellets Via Hot Melt ExtrusionRoblegg E; Jäger E; Hodzic A; Koscher G; Mohr S; Zimmer A; Khinast J.GEuro Physics Letterspaper refereed
2011Non-Destructive Analysis of Tablet Coatings with Optical Coherence TomographyKoller DM; Hannesschläger G; Leitner M; Khinast JGEuropean Journal of Pharmaceutical Sciencespaper refereed
2011Nanosuspensions as advanced printing ink for accurate dosing of poorly soluble drugs in personalized medicines Pardeike J; Strohmeier D.M; Schrödl N; Voura C; Gruber M; Khinast J.G; Zimmer AInternational Journal of Pharmaceutics paper refereed
2011Carrier-free Formulation of Dry Powder InhalatesMykhaylova V; Dresely K; Klar F; Urbanetz N.APharmaceutical Industrypaper refereed
2011Modeling and Simulation of Polyacrylic acid/Protamine Nanoparticle PrecipitationEitzlmayr A; Petschacher C; Radl S; Suzzi D; Zimmer A; Khinast J.GSoft Matterpaper refereed
2011Optimized carrier particles for dry powder inhalers by the use of spray dryingE. M. Littringer; A. Mescher; H. Schröttner; S. Schutting; P. Walzel; N. A. Urbanetz5th International Congress for Pharmaceutical Engineering Graz (A)oral presentation
2011Influence of process parameters on the D-mannitol particle formation during spray dryingE.M. Littringer; N.A. Urbanetz; A. Mescher; P. Walzel; H. Schröttner.8th European Congress of Chemical Engineering Berlin (D)oral presentation
2011Influence of droplet size on the crystallization behaviour of aqueous D-mannitol solutions during spray dryingLittringer E.M; Mescher A; Schröttner H; Maas S.G; Walzel P; Urbanetz N.AILASS2011 Estoril (P)oral presentation
2011The influence of carrier morphology on the fine particle fraction of dry powder inhaler formulationsLittringer E.M; Mescher A; Schröttner H; Walzel P; Urbanetz N.AJoint meeting of the austrian and german pharmaceutical societies Innsbruck (A)poster presentation
2011API-Crystallization in a continuous flow-deviceEder RJP; Grill J; Schmitt EK; Besenhard M; Schrank S; Roblegg E; Radl S; Gruber-Wölfler H; Khinast JG14. Österreichische Chemietage, Linz (A)poster presentation
2011Identification of disulfide-crosslinks in protein aggregatesHuettner B; Roessl U; Wiesbauer J; Nidetzky B; Birner-Gruenberger R2nd International Congress on Analytical Proteomics (ICAP) Ourense (Spain)oral presentation
2011Calcium Stearate Pellets: Drying Induced Variations in Dosage Form PropertiesSchrank S; Zimmer A; Glasser BJ; Khinast JG; Roblegg E5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)poster presentation
2011DoE Investigation of Tablet Coating using Non-invasive Methods and Dissolution TestingSchinwald S; Toschkoff G; Koller DM; Hannesschläger G; Leitner M; Frisch T; Reiter F; Straka G; Schlingmann M; Khinast JG5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)poster presentation
2011Effect of Plasticizers on the Development of Sustained-Release Lipophilic Calciumstearate Pellets produced via Hot-Melt ExtrusionJedinger N; Jäger E; Hodzic A; Koscher G; Mohr S; Zimmer A; Khinast JG; Roblegg E5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)poster presentation
2011Industrial PAT Use CasesWahl P; Scheibelhofer O; Koller DM; Straka G; Reiter F; Schlingmann M; Khinast J.G5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)poster presentation
2011Biological Control of Clean Room InhabitantsLiebminger S; Oberauner L; Aichner M; Cernava T; Bauer R; Berg G5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)oral presentation
2011Continuous-Flow API CrystallizationEder RJP; Grill J; Schmitt E; Schrank S; Roblegg E; Besenhard M; Radl S; Gruber-Wölfler H; Khinast JG5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)oral presentation
2011Formation of O/W emulsions by static mixers and production of microparticles for pharmaceutical applicationsKiss N; Brenn G; Pucher H; Wieser J; Scheler S; Jennewein H; Suzzi D; Khinast JG5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)oral presentation
2011Nebulization of Itraconazole-loaded NLC using a jet stream and an ultrasonic nebulizerWeber S; Zimmer A; Pardeike J5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)oral presentation
2011Monitoring of Pharmaceuticals Thermal Behavior by Combined Laboratory Small and Wide X-Ray Scattering (SWAXS) and Differential Scanning Calorimetry (DSC) Hodzic A; Fraser SD; Reiter F; Khinast JG; Lagger P5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)poster presentation
2011Multipoint Near-infrared Monitoring and Discrete Element Method Simulation of Fluid Dispensation in CatalystsHohl R; Heigl N; Radeke C; Scheibelhofer O; Balak N; Koller DM; Khinast JG5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)poster presentation
2011NIR-Imaging on Continuous Mixing ProcessesScheibelhofer O; Koller DM; Kerschhaggl P; Khinast JG5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)poster presentation
2011Optimization of Tablet Coating Processes using Discrete Element Method SimulationsToschkoff G; Suzzi D; Just S; Knop K; Kleinebudde P; Khinast JG5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)poster presentation
2011Particle Flow in an Innovative Fluid Bed Device Viewed by PEPTSalar-Behzad i S; Garguili J; Leadbeater T; Ingram A; Parker D; Seville J; Khinast JG; Viernstein H5th International Congress for Pharmaceutical Engineering (ICPE 2011), Graz (A)poster presentation
2011Formation of O/W Emulsions and Production of Microparticles for Pharmaceutical ApplicationsN. Kiss; D. Suzzi; J.G. Khinast.8th European Congress of Chemical Engineering, Berlin (D)poster presentation
2011Different reaction mechanism of beta-diketone cleavage in heme and non-heme Fe(II) enzymesLeitgeb S; Straganz Grit D; Nidetzky B9th European Biological Inorganic Chemistry Conference Wroclaw (PL)oral presentation
2011Improved therapeutic entities derived from known generics as an unexplored source of innovative drug productsStegemann S; Klebovich I; Antal I; Blume H; Magyar K; Németh G; Paál T.L; Stumptner W; Thaler G; Van de Putte A; Shah V.PEuropean Journal of Pharmaceutical Sciencespaper refereed
2011API Crystallization in a Continuous-Flow EquipmentEder RJP; Besenhard M; Schrank S; Roblegg E; Gruber-Wölfler H; Khinast J.GInternational Symposium on Industrial Crystallization, Zürich (CH)oral presentation
2011Evaluation of the effect of pH buffer and extremolytes on thermostability of G-CSF using differential scanning fluorimetry and design of experiments methodologyE. Ablinger; M. Hellweger; A. ZimmerJoint meeting of the austrian and german pharmaceutical societies Innsbruck (A)poster presentation
2011Robustness of an armored interface under elongationPlanchette C; Biance AL; Lorenceau EThe Eighth Liquid Matter Conference (LMC8), Wien (A)poster presentation
2011Innovative concepts for the management of microbial communities in clean roomsLiebminger S; Oberauner L; Zachow C; Berg GÖGMBT Jahrestagung, Salzburg (A)poster presentation
2011Using volatiles of plant-associated bacteria to control pathogens on plants as well as in clean roomsCernava T; Liebminger S; Vorauer F; Berg GÖGMBT Jahrestagung, Salzburg (A)poster presentation
2011Aspergillosis in falcons – Itraconazole-loaded Nanostructured Lipid Carriers (NLC) for pulmonary applicationPardeike J; Weber S; Zarfl H.P; Zimmer AÖPhG-DPhG-Jahrestagung 2011oral presentation
2011Nebulization of Itraconazole-loaded NLC using a jet stream and an ultrasonic nebulizerWeber S; Zimmer A; Pardeike JÖPhG-DPhG-Jahrestagung 2011poster presentation
2011Development and characterization of Dexamethasone-loaded Nanostructured Lipid Carriers (NLC) for pulmonary applicationS. Weber; J. Pardeike; H.P. Zarfl; A. Zimmer.ÖPhG-DPhG-Jahrestagung 2011 Innsbruck (A)poster presentation
2011Calcium Stearate Micro-pellets: Impact of Drying Conditions on Pellet DissolutionSchrank S; Reischl; Zimmer A; Khinast J.G; Roblegg EProcessNet Annual Meeting, Berlin (D)poster presentation
2011API-Crystal Preparation in a Continuously Seeded Tubular CrystallizerEder RJP; Grill J; Schmitt E; Schrank S; Roblegg E; Besenhard M; Radl S; Gruber-Woelfler H; Khinast JGAIChE Annual Meeting 2011, Minneapolis (USA)oral presentation
2011Formation of O/W emulsions by static mixers and production of microparticles for pharmaceutical applicationsN. Kiss; G. Brenn; H. Pucher; J. Wieser; S. Scheler; H. Jennewein; D. Suzzi; J.G. KhinastAIChE Annual Meeting. Minneapolis (USA)oral presentation
2011Investigation of Tablet Coating Processes using Discrete Element Method SimulationsToschkoff G; Suzzi D; Just S; Knop K; Kleinebudde P; Khinast JGAIChE Annual Meeting 2011, Minneapolis (USA)oral presentation
2011Multi-Scale Simulation of Tablet Coating ProcesseSuzzi D; Toschkoff G; Adam S; Radl S; Khinast J.GAIChE Annual Meeting 2011, Minneapolis (USA)oral presentation
2011Preparation of Calcium Stearate Pellets by Extrusion/Spheronization: Effect of Drying Technique Schrank S; Hodzic A; Glasser B; Zimmer A; Khinast JG; Roblegg EAIChE Annual Meeting 2011, Minneapolis (USA)oral presentation
2011Use of the Direct Compression Aid Ludiflash® for the preparation of pellets via wet extrusion/spheronizationRoblegg E; Schrank S; Griesbacher M; Radl S; Zimmer A; Khinast J.GDrug Development and Industrial Pharmacy paper refereed
2011Quantifying Absorption Effects during Hydrogen Peroxide DecontaminationRadl S; Larisegger S; Suzzi D; Khinast JGJournal of Pharmaceutical Innovation paper refereed
2011Kooperation bringt Erfolg - Vorzeigeprojekte aus der Cluster CommunityKlein T.Pharmazeutische Verfahrens-, Prozess- und Produktionstechnologie, executive lounge HTS, Graz (A)other
2011Innovative Konzepte in der ReinraumtechnologieLiebminger S.Zukunftskonferenz, Graz (A)other
2011Formulation development of granulocyte colony stimulating factor using a high-throughput fluorescence method and design of experimentsAblinger E; Hellweger M; Zimmer A5th International Congress for Pharmaceutical Engineering Graz (A)oral presentation
2011Continuous Monitoring of Powder Flow via NIR-ImagingScheibelhofer O; Koller D.M; Kerschhaggl P; Khinast JG7. Kolloquium Prozessanalytik, Linz (A)poster presentation
2011Multipoint NIR Spectroscopy vs. DEM Simulation for the Moisture Quantification During MixingHohl R; Heigl N; Radeke C; Scheibelhofer O; Koller DM; Khinast JG7. Kolloquium Prozessanalytik, Linz (A)poster presentation
2011NIR as a PAT Tool in Pharmaceutical ManufacturingWahl P; Scheibelhofer O; Koller D; Khinast JG7. Kolloquium Prozessanalytik, Linz (A)poster presentation
2011SIPAT for Monitoring of a Pharmaceutical Hot Melt Extrusion ProcessMarkl D; Wahl V; Koller D; Khinast J7. Kolloquium Prozessanalytik, Linz (A)poster presentation
2011Novel use of Small and Wide Angle X-Ray Scattering (SWAXS) to study the effects of dry granulation and compaction force on pharmaceutical tablet hardness Hodzic A; Llusa M; Khinast J.G; Fraser S; Heigl NAAPS Annual Meeting, Washington (USA)poster presentation
2011High throughput thermostability screening of granulocyte colony stimulating factor formulations by using design of experiments methodology Ablinger E; Hellweger M; Zimmer AFormulation Strategies for Protein Therapeutics-IBC's 11th Annual. Long Beach CA (USA)poster presentation
2011The influence of carrier shape and surface roughness of carrier-based dry powder inhalates on the fine particle fractionLittringer E.M; Mescher A; Schröttner H; Achelis L; Walzel P; Urbanetz N.ADrug Delivery to the Lungs 22 Edinburgh (UK)oral presentation
2011Numerische Simulation von Nanopartikel Präzipitation mittels PopulationsbilanzgleichungKhinast JGForum Technik und Gesellschaft, Förderpreis 2011, Graz (A)oral presentation
2011Calcium Stearate Micro-pellets: Impact of Drying Conditions on Pellet DissolutionSchrank S; Khinast JG; Roblegg EProcessNet, Aachen (D)poster presentation
2010Simultaneous Quantitative Analysis of Ternary Mixtures of Mannitol Polymorphs by FT-Raman Spectroscopy and Multivariate Calibration ModelsBraun D. E; Maas S. G; Zencirci N; Langes C; Urbanetz N. A; Griesser U. JInternational Journal of Pharmaceuticspaper refereed
2010Computational Simulation of Adhesion ForcesBresges C.; Urbanetz N. A.11th International Conference on Pharmacy and applied physical chemistry Innsbruck (A)oral presentation
2010Impact of excipients on coating efficiency in dry powder coatingSmikalla M; Urbanetz N. A.11th International Conference on Pharmacy and applied physical chemistry Innsbruck (A)oral presentation
2010The benefit of design of experiments (DOE) for studying the influence of spray drying conditions on particle morphologyLittringer E.M.; Urbanetz N.A.International Conference on Pharmacy and Applied Physical Chemistry (PhandTa) Innsbruck (A)poster presentation
2010Morphologie sprühgetrockneter Trägerpartikel für Pulverinhalatoren - Einfluss der ProzessparameterLittringer E. M; Mescher A; Schröttner H; Walzel P; Urbanetz N. AProcesnet Trocknungstechnik Göttingen (D)oral presentation
2010DEM Simulation feuchter Pulver im SchrägblattrührerRadeke C. A.; Khinast J. GJahrestreffen der ProcessNet-Fachausschüsse Fulda (D)oral presentation
2010Small and Wide Angle X-Ray Scattering (SWAXS) Laboratory Application in Solid-State Investigation for Pharmaceutical TechnologyHodzic APhandTA, Innsbruck (A)poster presentation
2010Mixing Characteristics of Wet Granular Matter in a Bladed MixerRadl S; Kalvoda E; Glasser BJ; Khinast JGPowder Technologypaper refereed
2010Modeling and Simulation of Complex Multiphase Flows in the Pharmaceutical IndustrySuzzi D; Toschkoff G; Hörmann T; Schaffer M; Machold D; Radeke C; Khinast JG; Sungkorn RSIMNET days 2010, Graz (A)oral presentation
2010Influence of spray drying conditions on the morphology of mannitol carrier particles intended for the use in DPILittringer E. M.; Mescher A.; Walzel P.; Urbanetz N. A.APV Meeting Valletta (MT)poster presentation
2010DNS of Bubble Swarms - How to Bridge the Scale Gap and Other AspectsRadl S; Khinast J. G12th Workshop on Two-Phase-Flow-Predictions, Halle (D)oral presentation
2010Scalar Variance and Fast Chemical Reactions in Bubble Column ReactorsRadl S; Khinast J. G; Gruber M. C12th Workshop on Two-Phase-Flow-Predictions, Halle (D)oral presentation
2010Detailed Numerical Simulations of Tablet Coating ProcesseSuzzi D; Toschkoff G; Radl S; Khinast JAPV Meeting, Valletta (MT)oral presentation
2010Development of a liquid ready-to-use controlled release suspension for pediatric applicationRoblegg E; Schrank APV Meeting, Valletta (MT)poster presentation
2010Development of calcium stearate based micropellets for controlled drug release Roblegg E., Schrank S.APV Meeting, Valletta (MT)poster presentation
2010Robust Monitoring of Pharmaceutical Powder Blend Quality with Combined PAT-Tools: NIR and Raman SpectroscopyKoller D; Posch A; Hörl G; Voura C; Fraser S; Tritthart W; Reiter F; Khinast JGAPV Meeting, Valletta (MT)poster presentation
2010Nano-Particles Production Processes: Modeling and Scale-upEitzlmayr A; Radl S; Suzzi D; Khinast JProjektkoordinations-Ausschuss NanoHealth, Schladming (A)oral presentation
2010Modifying Surface Topography of Mannitol Carriers for Dry Powder Inhalates by Spray DryingUrbanetz N. A.; Maas S. G.:APV Meeting Valletta (MT)poster presentation
2010Multiphase Simulation in the Pharmaceutical IndustrySuzzi D; Toschkoff G; Hörmann T; Radl S; Radeke C; Eitzlmayr A; Machold D; Khinast J. G11th ERCOFTAC Alpe Danube Adria PC Meeting, Graz (A)oral presentation
2010Continuous Manufacturing & the Role of HME in Pharmaceutical ProductionAdam S; Fraser SD; Koller D; Radl S; Suzzi D; Roblegg E; Khinast JGHot Melt Extrusion Congress, Stuttgart (D)oral presentation
2010Influence of process scale on the crystallization behaviour of spray dried D-MannitolLittringer E. M.; Maas S.; Mescher A.; Walzel P.; Urbanetz N. A.International school of crystallization. Granada Spainposter presentation
2010Surface modification of dry powder inhaler carrier particles by spray dryingLittringer E. M.; Mescher A.; Schröttner H.; Walzel P.; Urbanetz N. A.Spray 2010 Heidelberg (D)oral presentation
2010Application of PAT for in-line Monitoring of Powder Mixing Processes and Chemical Imaging of Pharmaceutical FormulationsKoller D; Heigl N; Hörl G; Voura C; Fraser S; Burgstaller M; Kerschhaggl P; Khinast J GEuPAT4 - Fourth pan-European Science Conference on Process Analytical Technology, Kuopio (FI)poster presentation
2010Numerical Simulation of Pharmaceutical Production Processes: towards Model Predictive Control (MPC) and QbD-based Simulation Design SpaceSuzzi D; Radl S; Toschkoff G; Adam S; Radeke C; Koller D; Khinast JGEuPAT4 - Fourth pan-European Science Conference on Process Analytical Technology, Kuopio (FI)oral presentation
2010Development of a QbD-based Simulation Design Space for Online PAT Control of Spray Coating ProcessesSuzzi D; Toschkoff G; Adam S; Radl S; Khinast JGEuPAT4 - Fourth pan-European Science Conference on Process Analytical Technology, Kuopio (FI)poster presentation
2010Experiences of the CRCsFraser S; Klein T. K; Khinast J. GCOMPERA IPR Workshop, Wien (A) other
2010Sprühtrocknung wässriger Mannitollösungen im Labor- und PilotmaßstabLittringer EM; Urbanetz NA6. Minisymposium VT, Tulln (A)poster presentation
2010Nanosprühtrocknung – ein ErfahrungsberichtUrbanetz N.A; Littringer E.MGastreferat Büchi Seminar Sprühtrocknung und Chromatographieoral presentation
2010Modeling Fast Reactions and Particle Flow - Applications of OpenFOAM in the Pharmaceutical Industry Radl S; Suzzi D; Khinast JG; Gruber MC; Eitzelmayr A5th OpenFOAM Workshop. Chalmers University, Gothenburg (SE)oral presentation
2010Comprehensive Modeling of Reactions in Multiphase FlowsRadl, S., Suzzi, D.; Khinast, J. G.; Gruber, M.C.; Eitzelmayr, A.6. Minisymposium der Verfahrenstechnik, Tulln (A)poster presentation
2010Elektrostatische Aufladung von pharmazeutischen Pulvern für die Anwendung in “Dry Powder Inhalers” (DPI)Urbanetz NA6. Minisymposium VT Tulln (A)poster presentation
2010Fast Reactions in Bubbly Flows - from DNS to Industrial-scale ReactorsRadl S; Suzzi D; Khinast JGISCRE 21, Philadelphia (USA)oral presentation
2010Bio-Nanotechnology Analytical Instrumentation and Methodology Application of Small and Wide Angle X-Ray Scattering (SWAXS)Hodzic AUniversität Sarajevo, Sarajevo (Bosnien-Herzegovina)oral presentation
2010Electrostatic complexation of human growth hormone with protamine for stabilization against deamidation Ablinger E; Wegscheider S; Pavkov T; Zimmer A; Keller W2010 Workshop on Protein Aggregation and Immunogenicity Breckenridge (USA)poster presentation
2010Stirred not shaken –process-relevant parameters and their effects on stability of human growth hormoneWiesbauer J; Leitgeb S; Nidetzky B2010 Workshop on Protein Aggregation and Immunogenicity Breckenridge (USA)poster presentation
2010Volatile organic compounds of plant-associated bacteria to reduce microbial contamination on clean room textileAichner M; Oberauner L; Liebminger S; Fürnkranz M; Berg GIOBC/WPRS Bulletinpaper refereed
2010Local analysis of the tablet coating process: Impact of operation conditions on film qualitySuzzi D; Radl S
Khinast JG
Chemical Engineering Sciencepaper refereed
2010Wet-Mixing of Powders, a Sarge Scale GPU Implementation Radeke C; Khinast J.GDEM5, London (UK)oral presentation
2010Structure-function relationships for substrate selectivity in 2-hydroxy acid oxidizing enzymesLeitgeb S; Stoisser T; Neuhold D; Nidetzky BThe 24th Annual Symposium of the Protein Society San Diego (USA)poster presentation
2010Surface modification of dry powder inhaler carrier particles by spray dryingLittringer E; Urbanetz N.A; Schröttner H; Maier M; Walzel P; Mescher A2. Workshop des SPP Prozess-Spray Erlangen (D)oral presentation
2010Electrostatic charge on pharmaceutical powders for pulmonary applicationUrbanetz N.A; Karner SCESPT 2010 Graz (A)poster presentation
2010Influence of carrier particle morphology on the performance of dry powder inhalersLittringer E; Urbanetz N.A; Maier M; Schröttner H; Mescher A; Walzel PCESPT 2010 Graz (A)poster presentation
2010Tailoring particle morphology of spray dried mannitol carrier particles by variation of the outlet temperatureLittringer E; Urbanetz N.A; Schrötter H; Walzel P; Mescher ALASS Europe 2010 Tschechische Republikoral presentation
2010Kinetic Pathway Analysis of Aggregation of Therapeutic Proteins Rößl U; Wiesbauer J; Leitgeb S; Nidetzky BCESPT 2010 Graz (A)oral presentation
2010Stabilization of human growth hormone against deamidation by interaction with strongly basic protamines from salmonAblinger E; Zimmer A; Prassl R8th Central European Symposium on Pharmaceutical Technology Graz (A)oral presentation
2010Multiphase Flow and Mixing in Dilute Bubble SwarmsRadl S; Khinast JGAIChE Journalpaper refereed
2010Development of micropellets for buccal drug deliverySchrank S; Khinast J.G; Roblegg E; Zimmer ACESPT 2010, Graz (A)poster presentation
2010Combined Numerical Method for Multi-Scale Analysis of Tablet Coating ProcessesSuzzi D; Toschkoff G; Machold D; Radl S; Khinast J.GCESPT 2010, Graz (A)oral presentation
2010Quality-by-Design Based Characterization of Pharmaceutical Processes by Means of Numerical SimulationsAdam S; Suzzi D; Radl S; Toschkoff G; Hörmann T; Khinast J.GCESPT 2010, Graz (A)oral presentation
2010Evaluation of API-Distribution and Coating Thickness by NIR
Spectroscopy and Raman Chemical Mapping
Hörl G; Heigl N; Koller D; Khinast J.G; Tritthart W; Reiter F; Schlingmann MCESPT 2010, Graz (A)poster presentation
2010Real-time Monitoring of Powder Mixing Dynamics with Spectroscopic PAT-ToolsKoller D; Balak N; Scheibelhofer O; Moor J; Hörl G; Heigl H; Fraser S.D; Khinast J.GCESPT 2010, Graz (A)oral presentation
2010Human growth hormone – insights into its aggregation behavior using denaturation pathway characterizationWiesbauer J; Leitgeb S; Nidetzky BCESPT 2010 Graz (A)poster presentation
2010Innovative Concepts for Personnel Locks in Clean Room Technology Liebminger S; Suzzi D; Fraser S; Schinagl G; Radl S; Oberauner L; Aichner M; Cardinale M; Khinast J.G; Berg GCESPT 2010, Graz (A)poster presentation
2010Kinetic Pathway Analysis of Aggregation of Therapeutic Proteins U. Rößl J. Wiesbauer S. Leitgeb B. Nidetzky.CESPT 2010 Graz (A)poster presentation
2010Linking Rheological Key Parameters of Pharmaceutical Powders to Mixing PropertiesScheibelhofer O; Balak N; Koller D; Fraser S.D; Khinast J.K; Freeman TCESPT 2010, Graz (A)poster presentation
2010Numerical simulation of film formation in tablet coatingToschkoff G; Suzzi D; Khinast J.G; Schlingmann M; Reiter F; Tritthart WCESPT 2010, Graz (A)poster presentation
2010Qualification of NIR Spectral Imaging for the Pharmaceutical IndustryMohr J; Koller D; Heigl N; Balak N; Khinast J:G; Burgstaller M; Kerschhaggl PCESPT 2010, Graz (A)poster presentation
2010Quantitative Quasi-Simultaneous and Spatially Resolved Real-time Monitoring of Powder Mixing Processes with a Multiple NIR-Probe SetupBalak N; Scheibelhofer O; Koller D; Khinast J.GCESPT 2010, Graz (A)poster presentation
2010Simulation of Fluid Mixing and Dissolution ProcessesHörmann T; Suzzi D; Gsöll M; Hofer J; Khinast J.GCESPT 2010, Graz (A)poster presentation
2010Stabilization of human growth hormone against deamidation by interaction with strongly basic protamines from salmonAblinger E; Wegscheider S; Pavkov T; Zimmer A; Keller W; Prassl RCESPT 2010 Graz (A)poster presentation
2010Particle Simulations using DEM on GPUsRadeke C; Khinast J.GGpu Technologie Conference 2010 (GTC), NVIDIA Research Summit, San Jose (USA)poster presentation
2010Fast Reactions in Bubbly Flows: Film Model and Micro-Mixing EffectsRadl S; Suzzi D; Khinast JGIndustrial & Engineering Chemistry Researchpaper refereed
2010Electrochemical tuning of the electrical resistance of nanoporous gold prepared by dealloying Wahl P; Traußnig T; Landgraf SInternational Conference on Nanostructured Materials, Rom (I)oral presentation
2010Survival of Human-Associated and Environmental Bacteria on Clean Room TextilesLiebminger S; Cardinale M; Oberauner L; Moschner C; Berg GInternational Microscopy Conference, Rio de Janeiro (Brasilien)poster presentation
2010Continuous Quantitative Monitoring of Powder Mixing Dynamics by Near-infrared SpectroscopyKoller DM; Posch A; Hörl G; Voura C; Radl S; Urbanetz NA; Fraser SD; Tritthart T; Reiter F; Schlingmann M; Khinast JGPowder Technologypaper refereed
2010CFD-Simulation eines Nanopartikel-Präzipitationsprozesses Eitzlmayr A; Suzzi D; Khinast J.GProcessNet-Jahrestagung 2010 und 28. Jahrestagung der Biotechnologen, Aachen (D)oral presentation
2010Entwicklung eines Extrusions-Spheronisationsprozesses zur Herstellung von rasch zerfallenden PelletsSchrank S; Khinast J.G; Roblegg E; Zimmer AProcessNet-Jahrestagung 2010 und 28. Jahrestagung der Biotechnologen, Aachen (D)oral presentation
2010Tailoring Surface Topography of Mannitol Carrier Particles for Dry Powder InhalationMaas S. G.; Schaldach G.; Walzel P. E.; Griesser U. J.; Urbanetz N. A.11th International Conference on Pharmacy and applied physical chemistry Innsbruck (A)oral presentation
2010The use of design of experiments to study the effect of process parameters on surface topography and size of spray dries D- mannitol Conference ProceedingsUrbanetz N.A; Littringer E; Schröttner H; Walzel P; Mescher AInternational Drying Symposium Magdeburg (D)oral presentation
2010Geriatric drug therapy: Neglecting the inevitable majorityStegemann S; Ecker F; Maio M; Kraahs F; Wohlfart R; Breitkreutz J; Zimmer A; Bar-Shalom D; Hettrich P; Broegmann BAgeing Research Reviewspaper refereed
2010Large-scale Powder Mixer Simulations Using Massively Parallel GPU ArchitecturesRadeke C.A; Glasser B.J; Khinast J.GChemical Engineering Sciencepaper refereed
2010Antagonistic endophytes from mistletoes as bio-resource to control clean room pathogensBerg G; Hartenberger K; Liebminger S; Zachow CIOBC/WPRS Bulletin paper refereed
2010Sustained release formulations by dry powder coating – Influence of starter cores on dissolution behaviorUrbanetz N.A.AAPS 2009 Annual Meeting and Exposition Los Angeles (USA)poster presentation
2010Tailoring dry powder inhaler performance by modifying carrier surface topography by spray dryingMaas S.G; Schaldach G; Walzel P.E; Urbanetz N.AAtomization and Sprayspaper refereed
2010Development of sustained release formulations by dry powder coating in a rotary fluid bedUrbanetz N.AAPS Annual Meeting Los Angeles (USA)oral presentation
2010Investigation of a Tablet Coating Processes using a Multi-Model Simulation ApproachToschkoff G; Suzzi D; Machold D; Radl S; Khinast JGAIChE Annual Meeting 2010, Salt Lake City (USA)oral presentation
2010Kinetic Pathway Analysis of Aggregation of Therapeutic ProteinsWiesbauer J; Rößl U; Leitgeb S; Nidetzky BAIChE Annual Meeting 2010, Salt Lake City (USA)oral presentation
2010Quantitative Quasi-Simultaneous and Spatially Resolved Real-time Monitoring of Powder Mixing Processes with a Multiple NIR-Probe SetupBalak N; Scheibelhofer O; Koller D.M; Khinast J.GAIChE Annual Meeting 2010, Salt Lake City (USA)oral presentation
2010Raman Spectroscopy Combined with Small- and Wide-Angle X-Ray Scattering as a Non-destructive Quality Control Tool
for Powder Compression in Pharmaceutical Applications
Heigl N; Hodzic A; Lachmann M; Fraser S.D; Khinast J.G; Kriechbaum M; Laggner P; Tritthart WAIChE Annual Meeting 2010, Salt Lake City (USA)oral presentation
2010Real-time Process Monitoring with Spatially Resolved Spectroscopic PAT-ToolsKoller D; Balak N;
Moor, J.;
Heigl, N.;
Fraser, S.D.; Khinast J.
AIChE Annual Meeting 2010, Salt Lake City (USA)oral presentation
2010Single Blade Experiments on Granular Flow and MixingRadl S; Khinast J.G; Glasser B; Haimburg H; Brandl DAIChE Annual Meeting 2010, Salt Lake City (USA)oral presentation
2010Wet-Mixing Simulations of Powders in a Blade MixerRadeke C; Khinast JGAIChE Annual Meeting 2010, Salt Lake City (USA)oral presentation
2010Aggregation of Recombinant Human Granulocyte-Colony Stimulating Factor under Process ConditionsRößlU; Wiesbauer J; Leitgeb S; Nidetzky BAIChE Annual Meeting 2010, Salt Lake City (USA)poster presentation
2010Pharmaceutical engineering science—New approaches to pharmaceutical development and manufacturingKhinast J.G; Muzzio FChemical Engineering Sciencepaper refereed
2010An integrated Quality by Design (QbD) approach towards design space definition of a blending unit operation by Discrete Element Method (DEM) simulationAdam S; Suzzi D;
Radeke C; Khinast JG
European Journal of Pharmaceutical Sciencespaper refereed
2010Kinetic Pathway Analysis of Aggregation of Therapeutic ProteinsLittringer E; Urbanetz N.A; Schröttner H; Walzel P; Mescher ADrug delivery to the lungs 21, Edinburgh (UK)oral presentation
2010Surface modification of mannitol inhaler carrier particles via spray dryingLittringer E; Urbanetz N.A; Schröttner H; Walzel P; Mescher ADrug delivery to the lungs 21, Edinburgh (UK)poster presentation
2010Polydisperse Granular Flows in a Bladed Mixer: Experiments and Simulations of Cohesionless SpheresRemy B; Khinast J.G; Glasser B.JChemical Engineering Sciencepaper refereed
2010Dry Powder Inhalers –the dependence of particle size and mixing time on triboelectrificationUrbanetz N.A; Karner SDrug delivery to the lungs 21, Edinburgh (UK)poster presentation
2010Antimikrobielle Textilien unter der LupeLiebminger S.Intensivtraining - Reinraumbekleidung/Der einzige Filter zwischen Mensch und Produkt Heidelberg (D)oral presentation
2010Impact of excipients on coating efficiency in dry powder coatingSmikalla M; Mescher A; Walzel P; Urbanetz N.AInternational Journal of Pharmaceuticspaper refereed
2010Mathematische Modellierung und SimulationstechnikenRadl, S., Khinast, J.Roadmap der chemischen Reaktionstechnik (Tagungsbericht)other
2009The Study of Different Solid Forms of EmodepsideBaronsky J; Bongaerts S; Traeubel M; Weiss HC; Urbanetz NAEuropean Journal of Pharmaceutics and Biopharmaceuticspaper refereed
2009Assessment of Micro- and Mesomixing in Bubble Swarms via SimulationsRadl S; Suzzi D; Khinast JGChemical Engineering Transactionspaper refereed
2009Oxidation of Secondary AlcoholsLiebminger SDoc Day – NAWI Graz Doctoral School; Graz (A)oral presentation
2009Naturwissenschaft im Allgemeinen BereichKlein TFIT an der TU Graz „Frauen in die Technik; (AT)other
2009Multiscale Simulation of Micro- and Mesomixing in Bubble SwarmsRadl S; Suzzi D; Khinast JGProcess Net Jahrestagung; Fulda (DE)oral presentation
2009Validated DEM Simulations of Wet Granular Matter in a BladedRadl S; Brandl D; Khinast JGProcess Net Jahrestagung; Fulda (DE)oral presentation
2009Pharmaindustrie in der SteiermarkKlein TClustertreffen Linz/Graz/Life Science Nord; Linz (AT)other
2009High-Throughput Phase-Diagram Mapping of Multicomponent Formulations by Scanning SAXS/SWAXS in the LaboratoryLaggner P; Herrnegger P; Hodzic A; Amenitsch H; Kriechbaum MMRS 2009; San Francisco (USA)oral presentation
2009Mechanisms of inactivation of the non-heme Fe2+-dependent dioxygenase Dke1Leitgeb SProStab 2009; Graz (AT)poster presentation
2009Mixing Characteristics of Wet Granular MatterRadl S; Brandl D; Khinast JGACHEMA 09; Frankfurt a. Main (DE)oral presentation
2009Assessment of Micro- and Mesomixing in Bubble Swarms via Simulations Radl S; Suzzi D; Khinast JGICheaP-9; Rom (I)oral presentation
2009Validation of Euler-Euler and Euler-Lagrange Approaches in the Simulation of Bubble Columns (Poster)Suzzi D; Radl S; Khinast JGICheaP-9; Rom (I)poster presentation
2009Steuerung der Leistungsmerkmale trägerbasierter Pulverinhalate durch gezielte Oberflächenmodifikation des Trägers mittels SprühtrocknungLittringer EM; Urbanetz NAKick-Off Meeting des DFG SPP 1423; Bremen (D)other
2009Stability of Dry Coated Solid Dosage FormsKablitz CD; Urbanetz NAPharmaceutical Development and Technologypaper refereed
2009Contact angle measurements as a screening tool for choosing excipients in dry powder coating processesSmikalla M; Urbanetz NAPharmSciFair 2009; Nice (F)oral presentation
2009New Developments in Laboratory X-Ray Nanoanalytics for Pharmazeutical ApplicationsHodzic ACMP-5 2009; New Brunswick (USA)poster presentation
2009Validation of Euler-Euler and Euler-Lagrange Approaches in the Simulation of Bubble SwarmsRadl S; Khinast JGChemical Engineering Transactionspaper refereed
2009Development of fast disintegrating pellet formulations based on Ludiflash®Khinast JG; Roblegg E; Radl S; Schrank SControlled Release Society, Kopenhagen (DK)poster presentation
2009Aufbau eines steirischen Forschungszentrums für Pharmazeutisches Engineering in Kooperation mit der Rutgers University (USA) – EndberichtRadl, S.;
Khinast, J.
Forschungsbericht, Rutgers University (USA)other
2009A Schrödinger-Poisson-Boltzmann system applied to the charge carrier transport in strained siliconToschkoff GXXI International Conference on Transport Theory; Turin (I)oral presentation
2009Influence of the Carrier Surface Fines on Dry Powder Inhalation FormulationsBoshhiha AM; Urbanetz NADrug Development and Industrial Pharmacypaper refereed
2009Laboratory SWAXS for Applications in Pharmaceutical TechnologyHodzic A; Kriechbaum M; Laggner PECM-25 2009; Istanbul (TR)oral presentation
2009Arbeitskreis 04: Biomedical and Pharmaceutical Engineering - Schlüsseltechnologien des 21. JahrhundertsKhinast JGForum Alpbach 2009; Alpbach (A)other
2009Solid form analysis with special consideration of perfusion calorimetryUrbanetz NA; Baronsky J; Traeubel MInternational Congress for Pharmaceutical Engineering; Graz (A)oral presentation
2009Tailor-made carrier particles for dry powder inhalersLittringer EM; Urbanetz NAInternational Congress for Pharmaceutical Engineering; Graz (A)poster presentation
2009Isothermal Microcalorimetry Perfusion Experiments: A Method to Verify the Relative Vapour Pressure of Organic Liquids inside the Sample VesselBaronsky J; Bongaerts S; Traeubel M; Urbanetz NAThermochimica Actapaper refereed
2009Gesundheitsgespräche - Medizinischer Fortschritt: Chance oder Belastung?Khinast JGForum Alpbach 2009; Alpbach (A)other
2009Analysis of microdrops for the production of personalized drugsVoura C; Drage P; Gruber M; Khinast JGInternational Congress for Pharmaceutical Engineering; Graz (A)oral presentation
2009Size Effects and Agglomerate Formation in Granular FlowsRadl S; Khinast JG; Brandl D; Heimburg H; Siraj MInternational Congress for Pharmaceutical Engineering, Graz (A)oral presentation
2009Survival of human-associated bacteria on clean room clothingLiebminger S; Hartenberger KInternational Congress for Pharmaceutical Engineering, Graz (A)oral presentation
2009SWAXS for Applications in Pharmaceutical TechnologyHodzic A; Khinast JG; Kriechbaum M; Tritthart W; Reiter F; Laggner PInternational Congress for Pharmaceutical Engineering, Graz (A)oral presentation
2009Tablet coating: Detailed numerical analysisSuzzi D; Khinast JG; Radl SInternational Congress for Pharmaceutical Engineering, Graz (A)oral presentation
2009Computational Analysis and Experimental Evaluation of a Drum Coating ProcessToschkoff G; Suzzi D; Fraser SD; Khinast JG; Reiter F; Tritthart WInternational Congress for Pharmaceutical Engineering, Graz (A)poster presentation
2009Development of an extrusion spheronisation technique for the preparation of fast disintegrating pelletsRoblegg E; Schrank S; Radl S; Khinast JGInternational Congress for Pharmaceutical Engineering, Graz (A)poster presentation
2009Monitoring powder uniformity of pharmaceutical blends using Near-infrared spectroscopyPosch A; Voura C; Hörl G; Khinast JGInternational Congress for Pharmaceutical Engineering, Graz (A)poster presentation
2009Optimization of Particle Simulations using online Process MonitoringRadeke C; Posch A; Hörl G; Radl S; Voura C; Fraser S; Khinast JGInternational Congress for Pharmaceutical Engineering, Graz (A)poster presentation
2009Simulation of mixing processes for the manufacture of pharmaceutical productsHörmann T; Redlinger-Pohn J; Schaffer M; Suzzi D; Radl S; Khinast JGInternational Congress for Pharmaceutical Engineering, Graz (A)poster presentation
2009Ein rigoroses Modell des reaktiven Stofftransportes in großen BlasenschwärmenKhinast JGProcessNet-Jahrestagung 2009, Mannheim (D)oral presentation
2009Wet Granular Flows - Impact of Cohesion on Particle MixingRadl S; Khinast JG; Brandl D; Siraj MProcessNet-Jahrestagung 2009, Mannheim (D)oral presentation
2009DEM and QbD: Validation Studies towards a Virtual Design SpaceSuzzi D; Adam S; Radl S; Fraser S; Voura C; Koller D; Khinast JG; Brandl D; Heimburg H; Siraj SMMedeso Pharma Seminar, Kopenhagen (DK)poster presentation
2009Tailor-made carrier particles for dry powder inhalersLittringer E.M.; Urbanetz N.A.Mitarbeiter Workshop DFG SPP 1423 Hamburg (D)oral presentation
2009A Rigorous Model for Mass Transfer, Chemical Reactions and Mixing in Large Bubble and Droplet SwarmsRadl S; Khinast JG; Suzzi D; Brandl D; Glasser B; Remy BAIChe Annual Meeting 2009, Nashville (USA)oral presentation
2009CFD Prediction of Liquid Homogenization with Variable Viscosity in a Stirred TankHörmann T; Schaffer M; Redlinger-Pohn J; Khinast JGAIChe Annual Meeting 2009, Nashville (USA)oral presentation
2009Detailed Numerical Analysis of Tablet Coating ProcessesSuzzi, D.; Egger, D.; Radl, S.; Khinast, J. G.; Reiter, F.; Tritthart, W.AIChe 2009, Nashville (USA)oral presentation
2009Implementing Risk- and Knowledge Management Tools Into Product- and Process Development According to Quality by Design Gübitz B; Adam S; Radl S; Khinast JG; Fritz J; Schnedl HAIChe Annual Meeting 2009, Nashville (USA)oral presentation
2009Improving Drum Coating Processes by Computational Modeling and Experimental EvaluationToschkoff, G.; Suzzi, D.; Khinast, J. G.; Reiter, F.; Tritthart, W.:AIChe 2009, Nashville (USA)oral presentation
2009Validated DEM Simulations of Wet Granular Matter in a Bladed MixerRadl S; Khinast JG; Brandl D; Glasser B; Remy BAIChe Annual Meeting 2009, Nashville (USA)oral presentation
2009Laboratory SWAXS for Applications in Pharmaceutical TechnologyHodzic A; Khinast J. G; Kriechbaum; Tritthart W; Reiter F; Laggner PAIChe Annual Meeting 2009, Nashville (USA)poster presentation
2009Robust monitoring of pharmaceutical manufacturing operations based on combined NIR and Raman spectroscopyVoura C; Posch A; Hörl G; Koller D; Fraser S; Reiter F; Walter T; Khinast JGAIChe Annual Meeting 2009, Nashville (USA)poster presentation
2009Neue Werkstoffe für maßgeschneiderte HeilmittelKlein, T.Zukunftsdialog - Stoffe aus denen die Zukunft ist, Leoben (A)other
2009The Role of Membrane Hydrocarbon Chain Composition in Interactions with Antihypertensive DrugsHodzic A; Zoumpoulakis P; Mavrmoustakos T; Rappolt M; Laggner P.; Pabst G4th Christmas Biophysics Workshop, XBW 2009, Leibnitz (A)oral presentation
2009A Novel Design for Hot-Melt Extrusion PelletizersRadl S; Tritthart T; Khinast JGChemical Engineering Sciencepaper refereed
2009Granular Flows – Showing Size Effects By Using High-Performance Simulations On GPUSRadeke CA; Radl S; Khinast JGCSIRO Multiscale Modeling Symposium (Proceedings CD), Melbourne (AU)oral presentation
2009High Performance Simulation of Bubbly Flows: Pushing the Limit by Using Conventional CFD and LBGKRadl S; Khinast JG; Suzzi D; Sungkorn R; Derksen JCSIRO Multiscale Modeling Symposium (Proceedings CD), Melbourne (AU)oral presentation
2009Forschung für das 21. Jahrhundert / Zentrumsstruktur und ProjektabwicklungKhinast, J.;
Klein, T.
FFS RCPE - We make tomorrow´s drugs possible, Graz (A)other
2009Capillary Force Promoters and Plasticizers for the Dry Coating Process – Differencesin Substances and PropertiesUrbanetz N.A.:European Journal of Pharmaceutics and Biopharmaceutics paper refereed
2008Nanotechnology: Developments in Laboratory X-Ray Nanoanalytics Bridging the Gap to SynchrotronsHodzic A; Kriechbaum M; Laggner PHacettepe University (Ankara) 2008oral presentation
2008Modeling Hot-Melt Extrusion PelletizersRadl S; Tritthart T; Khinast JGAICHE 2008; Philadelphia (USA)oral presentation
2008New Perspectives for Reactive Mixing in Multiphase FlowsRadl S; Khinast JGAICHE 2008; Philadelphia (USA)oral presentation
2008Using DEM to Identify Mixing Mechanisms in Blading MixersRadl S; Glasser BJ; Khinast JGAICHE 2008; Philadelphia (USA)oral presentation
2008Numerische Simulation von gekoppelten SystemenUnterreiter G; Suzzi DSIMNET Days 2008; Leoben (A)oral presentation
2008Mehrphasenströmung in der Pharmazeutischen IndustrieKhinast JG; Radl S; Santagati P; Sungkorn RSIMNET Days 2008; Leoben (A)oral presentation
2008Das RCPE und künftige Entwicklungen in der BiotechnologieSuzzi D; Khinast JGSeminar für Pharma & Life Science: Mikrobiologie in der pharmazeutischen Industrie; Neustadt an der Weinstraße (AT)other
2008Projektvorstellung Quality by DesignGübitz BQuality by Design Workshop; RCPE; Graz (A)other
2008Pharmaceutical Engineering TrendsKlein TEuropean Pharmaceutical Enterprises; Brüssel (BE)other
2008Research Center Pharmaceutical EngineeringKlein TEuropean Pharmaceutical Enterprises; Brüssel (BE)other
2008Trends in der Pharmabranche. Quality by DesignKhinast JGFast Forward „Regulatorische Trends in der Entwicklung”; Roche Diagnostics; Graz (AT) other
2008Chairman -MehrphasensimulationKlein TSIMNET Days 2008; Leoben (A)other

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