Accelerating Access to Medicines

APRIL 01 & 02, 2025 // WASHINGTON, D.C.

Thank you for Attending

The “Accelerating Access to Medicines” workshop, held April 01-02, 2025, at the Austrian Embassy in Washington DC, convened leading experts from pharmaceutical companies, equipment providers, academia, and RCPE.

The event addressed critical bottlenecks in pharmaceutical development pipelines and explored innovative strategies to significantly expedite patient access to medicines. Against the backdrop of increasing product complexity, fragile supply chains, and rising demand for personalized medicine, participants examined the latest advancements in pharmaceutical manufacturing.

Key topics included innovations in nano-drugs, solid dosage forms, biologics, digitalization strategies, advanced Process Analytical Technologies (PAT), flow chemistry, continuous manufacturing processes, and on-demand production technologies.

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Attendees

Download: List of Attendees – AATM 2025

Oral Presentations

Benedict Benque
RCPE
In Silico Insights into the Tablet Manufacturing Process

Matthew M. Bio
SNAPDRAGON CHEMISTRY / A CAMBREX COMPANY
Complex synthetic APIs and the evolution process development and manufacturing

Thomas Brinz
Syntegon
Optimizing Processes and Improving Quality in Tablet Compression and Encapsulation – A New Way of Supervised Machine Learning

Ananya Chowdhury
SIEMENS
Leveraging mechanistic and data-driven models for digitalization across the pharmaceutical lifecycle

Sharon Flank / Martin Spörk
INFRATRAC / RCPE
3D Drug Printing: A Technology Ready to Improve Patient Health

Michael Gosselin
APRECIA PHARMACEUTICALS
Industry Perspective: Current and Future Applications of 3D Printing in Pharma

Nicolin Govender
UNIVERSITY COLLEGE LONDON
Towards manufacturing digital twins using GPU based multi-physics simulations

Marc Horner
ANSYS, Inc.
Enabling the Credibility of Knowledge-Based and Data-Based Models for Pharma/Biopharma

Oliver Kappe
RCPE
Sustainable Chemical Processing Using Flow Technology

Thomas Kipping
MERCK DARMSTADT
Transforming challenges into solutions: 3D printing for oral drug delivery

Michaela Laussegger
ABA
Austria: Top Center for Life Sciences

Josip Matić
RCPE
Digital Tools for Extrusion Process Design

Silke Möschter
IOI OLEO GMBH
Solubilisation of a BCS-class II drug substance with a new lipid-based excipient

G. Gary Norman
DFE PHARMA
Understanding Powder Behavior in Continuous Feeding: Powder Densification, and Screw Layering

Sharon Nowak
COPERION/COPERION K-TRONHOVIONE
Impacts of Excipient Flow Properties on Feeding of Continuous Pharmaceutical Processes and Solutions for Overcoming these Challenges by both Excipient Formulators and Equipment Designers

Ettigounder (Samy) Ponnusamy
MILLIPORE SIGMA
DOZN™2.1 – A Quantitative Green Chemistry Evaluator for a Sustainable Future

Owen Rehrauer
SENTRONIC US
Multivariate Model Calibration Burden Comparison for a Simplified Continuous Manufacturing Formulation

Andreas Wagner
POLYMUN SCIENTIFIC
Pioneering a versatile LNP production process for mRNA vaccines, therapeutics and gene editing – Unveiling the proof of concept

Martin Warman
Martin Warman Consultancy Ltd
Manufacturing at Point of Care to Ensure Robust Supply Chains

Christian Witz
SIMVANTAGE
Advanced Process Simulation for Efficient Biopharma Scale-Up

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Key Topics Discussed

The workshop offered an engaging and insightful platform where industry experts and professionals came together to explore cutting-edge advancements in drug development, product manufacturing, and supply chain optimization.

Designed for pharmaceutical companies, equipment providers, CDMOs, biotech firms, academia, and supply chain specialists, the event provided valuable opportunities to deepen knowledge and foster strategic partnerships.

The central theme of the workshop was the Rapid Development of Products and Processes, with sessions covering the following key areas:

Click the topic for more details:

DRUG SUBSTANCE: APIs & BIOLOGICS

> Explored the latest trends and challenges in the development and production of Active Pharmaceutical Ingredients (APIs) and biologics.

> Experts dove into new technologies, regulatory considerations, and best practices in scaling up the production of complex drug substances.

DRUG PRODUCT: FROM PILLS TO INJECTABLES

> Covered the transition from traditional pill-based formulations to injectable products, focusing on advanced drug delivery systems, formulation challenges, and innovations in patient-centric design.

> Showcased how drug product development can be optimized for enhanced efficacy and market success.

TECHNOLOGY PLATFORMS: PRIMARY & SECONDARY

> Delved into cutting-edge technology platforms that support both primary and secondary pharmaceutical production.

> The discussion included automation, data integration, and novel manufacturing techniques, highlighting their role in increasing efficiency, reducing costs, and maintaining quality standards.

DERISKING SUPPLY CHAINS & TRANSATLANTIC PARTNERSHIPS

> Addressed strategies for mitigating risks, improving resilience, and leveraging transatlantic partnerships to secure and streamline supply chains across borders.

> Provided insights into navigating regulatory challenges and fostering collaboration between the U.S. and European markets.

MODELING AND SIMULATION: FROM MOLECULES TO PRODUCTS

> Demonstrated how advanced modeling and simulation techniques accelerated the drug development process from molecular discovery to final product formulation.

> Showed how digital tools are revolutionizing research, enabling predictive analysis, and improving decision-making in drug development pipelines.

> Model-based process and product development

> Risk and sensitivity analysis, multidimensional virtual DoEs

> M&S from discovery to manufacturing

100

PARTICIPANTS

540

MINUTES OF USE CASES

30

SPEAKERS

8

HOURS TO NETWORK

Keynote Speakers

JOHANNES KHINAST

RCPE / GRAZ UNIVERSITY OF TECHNOLOGY (AT)

ANANYA CHOWDHURY

SIEMENS

MATTHEW M. BIO

SNAPDRAGON CHEMISTRY, A CAMBREX COMPANY

LUCA EMILI

INSILICOTRIALS (IT)

NICOLIN GOVENDER

UNIVERSITY COLLEGE LONDON

Program 2025

Click the session title for more details:

WELCOME & PLENARY LECTURE

Johannes Khinast
RCPE / GRAZ UNIVERSITY OF TECHNOLOGY

SESSION 01: DRUG SUBSTANCE: APIs & BIOLOGICS

Matthew M. Bio
SNAPDRAGON CHEMISTRY / A CAMBREX COMPANY
Complex synthetic APIs and the evolution process development and manufacturing

Iben Østergaard
LUNDBECK
Complexities in solid form and crystallization process design: An industry case study on macrocyclic molecules

Jadid Samad
PFIZER
Continuous API Manufacturing Technologies at Pfizer

Ettigounder (Samy) Ponnusamy
MILLIPORE SIGMA
DOZN™2.1 – A Quantitative Green Chemistry Evaluator for a Sustainable Future

Oliver Kappe
RCPE
Sustainable Chemical Processing Using Flow Technology

SESSION 02: DRUG PRODUCT: FROM PILLS TO INJECTABLES

Andreas Wagner
POLYMUN SCIENTIFIC
Pioneering a versatile LNP production process for mRNA vaccines, therapeutics and gene editing – Unveiling the proof of concept

Filip Francqui
GRANUTOOLS
Understanding the relation between permeability and packing fraction to improve tablet manufacturing

Martin Spörk/Sharon Flank
RCPE/INFRATRAC
3D Drug Printing: A Technology Ready to Improve Patient Health

Silke Möschter
IOI OLEO GMBH
Solubilisation of a BCS-class II drug substance with a new lipid-based excipient

SESSION 03: TECHNOLOGY PLATFORMS: PRIMARY & SECONDARY

Luca Emili
INSILICOTRIALS (IT)
Revolutionizing Drug Development: In Silico Trials as the Catalyst for Efficiency and Innovation

Thomas Kipping
MERCK DARMSTADT
Transforming challenges into solutions: 3D printing for oral drug delivery

Ali Rajabi-Siahboomi
COLORCON
An excipient supplier’s perspectives on digital tools and their applications

Thomas Brinz
SYNTEGON TECHNOLOGY GMBH
Optimizing processes and increasing efficiency by automation in tablet compression and encapsulation – a new way of supervised machine learning

Owen Rehrauer
SENTRONIC US
Multivariate Model Calibration Burden Comparison for a Simplified Continuous Manufacturing Formulation

Sarang Oka
HOVIONE
Simplifying Continuous Direct Compression: Reducing Barriers for Accelerating Adoption

Norman, G. Gary
DFE PHARMA
Understanding Powder Behavior in Continuous Feeding: Powder Densification, and Screw Layering

Michael Gosselin
APRECIA PHARMACEUTICALS
Industry Perspective: Current and Future Applications of 3D Printing in Pharma

SESSION 04: MODELING AND SIMULATION: FROM MOLECULES TO PRODUCTS

Nicolin Govender
UNIVERSITY COLLEGE LONDON
Towards manufacturing digital twins using GPU based multi-physics simulations

Ananya Chowdhury
SIEMENS
Leveraging mechanistic and data-driven models for digitalization across the pharmaceutical lifecycle

Sal Garcia
ELI LILLY AND COMPANY
Using fundamental models for process monitoring using State Estimation techniques

Christian Witz
SIMVANTAGE
Advanced Process Simulation for Efficient Biopharma Scale-Up

Maitraye Sen
ELI LILLY AND COMPANY
Use of discrete element and finite element methods to identify potential causes of tablet defects during manufacturing

Neda Nazemifard
TAKEDA
In Silico Strategies for Process Design, Optimization, and Scale-Up for Pharmaceutical Compounds: Enhancing Predictability, Efficiency, and Speed

Sandra Suarez-Sharp
SIMULATIONS PLUS
Empowering QC Dissolution Methods Via PBBM and Cross-Validation in the Late Stages of Drug Product Development

Marc Horner
ANSYS, Inc.
Enabling the Credibility of Knowledge-Based and Data-Based Models for Pharma/Biopharma

Josip Matic
RCPE
Talk Title: to be announced soon

SESSION 05: DERISKING SUPPLY CHAINS & TRANSATLANTIC PARTNERSHIPS

Michaela Laussegger
ABA
Austria: Top Center for Life Sciences

Gregory Connelly
VERTEX
Continuous Improvement for Continuous Manufacturing: 10 Years of CM at Vertex

Martin Warman
tbd
Manufacturing at Point of Care to Ensure Robust Supply Chains

SESSION 06: PANEL DISCUSSION

RCPE and Pharma Industry
RCPE
moderated by Caroline Schober

Accelerating Access to Medicines

Thank you for Attending

Attendees

Oral Presentations

Partners & Sponsors 2025